Projects per year
Personal profile
Personal Statement
Glenn A. Burley (GAB) is Professor of Chemical Biology at the University of Strathclyde. The main focus of GAB’s research programme is the development of molecular probes to further our understanding of processes involved in gene expression. GAB was awarded a Bachelor of Medicinal Chemistry (Hon. I) and a PhD in Organic Chemistry from the University of Wollongong, Australia. GAB was a post-doctoral fellow in the Fullerene Science Centre at the University of Sussex (2001-2003) and an Alexander von Humboldt Fellow at the University of Munich (2004-2006). GAB began his independent career as an EPSRC Advanced Fellow in 2007 at the University of Leicester, before moving to Strathclyde in 2011.
More information can be found at: www.burleylabs.co.uk
Research Interests
The Burley group (www.burleylabs.co.uk) applies a problem-based ethos that utilizes synthetic organic chemistry, biocatalysisand physical organic chemistry to explore regulatory mechanisms of transcription and RNA processing. A second research area of interest is the development of bio-orthogonal chemistries to prepare bioconjugates for cell selective drug delivery.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Gene Solutions Extension June-August 2025
Burley, G. (Principal Investigator) & MacKay, S. (Co-investigator)
1/06/25 → 31/08/25
Project: Research
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TargoPep: A cell-selective Therapeutic Oligonucleotide Delivery Platform
Burley, G. (Principal Investigator), MacKay, S. (Co-investigator), Rattray, Z. (Co-investigator) & McWhinnie, F. (Research Co-investigator)
BBSRC (Biotech & Biological Sciences Research Council)
1/01/25 → 31/12/26
Project: Research
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Preparation of nucleoside analogues: opportunities for innovation at the interface of synthetic chemistry and biocatalysis
Salihovic, A., Taladriz-Sender, A. & Burley, G. A., 5 Jun 2025, (E-pub ahead of print) In: Chemical Science.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Expanding the reaction toolbox for nanoscale direct-to-biology PROTAC synthesis and biological evaluation
Stevens, R., Shrives, H. J., Cryan, J., Klimaszewska, D., Stacey, P., Burley, G. A., Harling, J. D., Battersby, D. J. & Miah, A. H., Mar 2025, In: RSC Medicinal Chemistry. 16, 3, p. 1141-1150 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure)
Datasets
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Data for: "A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications"
Stacey, P. (Creator), Lithgow, H. (Creator), Lewell, X. (Creator), Konopacka, A. (Creator), Besley, S. (Creator), Green, G. (Creator), Whatling, R. (Creator), Law, R. (Creator), Röth, S. (Creator), Sapkota, G. P. (Creator), Smith, I. E. D. (Creator), Burley, G. A. (Creator), Harling, J. (Creator), Benowitz, A. B. (Creator), Queisser, M. A. (Creator) & Muelbaier, M. (Creator), figshare, 16 Mar 2023
DOI: 10.25384/sage.c.5443031.v1
Dataset
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Data for: "Sequence-selective minor groove recognition of a DNA duplex containing synthetic genetic components"
Padroni, G. (Creator), Withers, J. M. (Creator), Taladriz-Sender, A. (Creator), Reichenbach, L. F. (Creator), Parkinson, J. A. (Creator) & Burley, G. A. (Creator), Biological Magnetic Resonance Bank, 17 Oct 2023
DOI: 10.13018/bmr34397, https://doi.org/10.13018/BMR34328
Dataset
Activities
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LINXS Chemistry of Life Meeting
Burley, G. (Speaker)
18 Oct 2024Activity: Talk or presentation types › Invited talk
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Mechanism inspired ynamine modification of biomolecules
Burley, G. (Speaker)
9 Jun 2024 → 14 Jun 2024Activity: Talk or presentation types › Invited talk