• United Kingdom

Accepting PhD Students

1987 …2023
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Research Output 1987 2019

2019
1 Citation (Scopus)

Characterisation and optimisation of diclofenac sodium orodispersible thin film formulation

Khadra, I., Obeid, M. A., Dunn, C., Watts, S., Halbert, G., Ford, S. & Mullen, A., 20 Apr 2019, In : International Journal of Pharmaceutics. 561, p. 43-46 4 p.

Research output: Contribution to journalArticle

Diclofenac
Water
Drug Delivery Systems
Pharmaceutical Preparations
Tooth
2 Citations (Scopus)
Extrusion
Printing
Fabrication
Chemical analysis
Pharmaceutical Preparations
1 Citation (Scopus)
Saccharin
Indomethacin
Dimers
Compaction
dimers

The topography of simulated intestinal equilibrium solubility

Dunn, C., Perrier, J., Khadra, I., Wilson, C. G. & Halbert, G. W., 6 May 2019, In : Molecular Pharmaceutics. 16, 5, p. 1890-1905 16 p.

Research output: Contribution to journalArticle

Open Access
File
Solubility
Bile Acids and Salts
Phospholipids
Pharmaceutical Preparations
Monoglycerides
Open Access
File
Terahertz Spectroscopy
Raman Spectrum Analysis
Solubility
Pharmaceutical Preparations
Polymers
Open Access
File
Terahertz Spectroscopy
Raman Spectrum Analysis
Solubility
Pharmaceutical Preparations
Polymers
2018

Drug to patient: pharmaceutical and scientific collaboration

Halbert, G., 2 Sep 2018. 5 p.

Research output: Contribution to conferenceKeynote

Open Access
File
13 Citations (Scopus)

Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations

Brown, C. J., McGlone, T., Yerdelen, S., Srirambhatla, V., Mabbott, F., Gurung, R., Briuglia, M. L., Ahmed, B., Polyzois, H., McGinty, J., Perciballi, F., Fysikopoulos, D., Macfhionnghaile, P., Siddique, H., Raval, V., Harrington, T. S., Vassileiou, A., Robertson, M., Prasad, E., Johnston, A. & 9 othersJohnston, B., Nordon, A., Srai, J., Halbert, G., Ter Horst, J. H., Price, C. J., Rielly, C. D., Sefcik, J. & Florence, A. J., 1 Jun 2018, In : Molecular Systems Design & Engineering. 2018, 3, p. 518-549 32 p.

Research output: Contribution to journalArticle

Open Access
File
Workflow
Crystallization
Drug products
Cooling
Pharmaceutical Preparations

Equilibrium solubility in simulated intestinal media

Halbert, G., Dunn, C., Khadra, I. & Wilson, C., 17 Sep 2018. 20 p.

Research output: Contribution to conferenceKeynote

Open Access
File

Injection moulding- A novel method of solid oral dosage form manufacturing

Wood, S., Halbert, G. & Florence, A., 18 Jan 2018. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
Dosage Forms
Injections
Polymers
Pharmaceutical Preparations
Pressure
Open Access
File
Printing
Dosage Forms
Polymers
Pharmaceutical Preparations
Powders

Novel formulation and biopharmaceutical challenges of oral cancer therapy

Halbert, G., 5 Sep 2018. 33 p.

Research output: Contribution to conferenceKeynote

Open Access
File
7 Citations (Scopus)
Open Access
File
Solubility
Pharmaceutical Preparations
aprepitant
Probucol
Felodipine

The impact of channel fill level on internal forces during continuous twin screw wet granulation

Torrecillas, C. M., Gorringe, L. J., Rajoub, N., Robertson, J., Elkes, R. G., Lamprou, D. A. & Halbert, G. W., 28 Dec 2018, In : International Journal of Pharmaceutics. p. 1-43 43 p.

Research output: Contribution to journalArticle

Torque
Particle Size
Powders
Rupture
Coloring Agents
2017
4 Citations (Scopus)
Open Access
File
Particle Size
Excipients
Torque
Lactose
Powders

'Build a release' achieving polymer based disintegrating tablets

Wood, S. & Halbert, G., 15 Jun 2017. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
3 Citations (Scopus)
Open Access
File
Solubility
Pharmaceutical Preparations
Bile Acids and Salts
Monoglycerides
Intestinal Absorption

Example use of screening and analytical tools for secondary processing

Prasad, E., Islam, M., Robertson, J. & Halbert, G., 9 Nov 2017. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
3 Citations (Scopus)
Open Access
File
Surface-Active Agents
Solubility
Pharmaceutical Preparations
Lecithins
aprepitant
Open Access
File
Printing
Dosage Forms
Solubility
Pharmaceutical Preparations
Drug and Narcotic Control

Solid oral dosage form manufacturing using injection moulding

Wood, S., Halbert, G. & Florence, A., 23 Mar 2017.

Research output: Contribution to conferencePoster

Open Access
File
Dosage Forms
Polymers
Injections
Pharmaceutical Preparations
Solubility

Solid oral dosage form manufacturing using injection moulding

Wood, S., Halbert, G. & Florence, A., 16 Oct 2017. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
17 Citations (Scopus)
Open Access
File
Solubility
Oleic Acid
Pharmaceutical Preparations
Bile Acids and Salts
Lecithins

The pharmaceutical challenge of cancer research

Halbert, G., 12 May 2017, (Unpublished) 25 p. Glasgow : University of Strathclyde.

Research output: Other contribution

File
2016

Achieving immediate release dosage forms using DoE and injection moulding

Wood, S., Halbert, G. W. & Florence, A., 30 Nov 2016. 1 p.

Research output: Contribution to conferencePoster

File
Polyvinyl Alcohol
Dosage Forms
Injections

An investigation into drug content uniformity in fused filament fabrication

Brammer, E., Halbert, G. & Lamprou, D., 17 Nov 2016, (Unpublished). 1 p.

Research output: Contribution to conferencePoster

Pharmaceutical Preparations
Secondary Ion Mass Spectrometry
Tablets
Polymers
Printing

An investigation into fused filament fabrication for pharmaceutical manufacturing

Brammer, E. M., Halbert, G. W. & Lamprou, D. A., 7 Apr 2016, (Unpublished).

Research output: Contribution to conferencePoster

File
Point-of-Care Systems
Aptitude
Pharmaceutical Preparations
Body Weight
27 Citations (Scopus)

A novel hot-melt extrusion formulation of albendazole for increasing dissolution properties

Martinez Marcos, L., Lamprou, D., McBurney, R. & Halbert, G., 29 Feb 2016, In : International Journal of Pharmaceutics. 499, 1-2, p. 175-185 11 p.

Research output: Contribution to journalArticle

Open Access
File
Albendazole
Powder Diffraction
Differential Scanning Calorimetry
X-Ray Diffraction
Electron Scanning Microscopy
Open Access
File
Chromatography
Drug products
Cleaning
Pharmaceutical Preparations
United States National Aeronautics and Space Administration
4 Citations (Scopus)

Evaluation of the impact of excipients and an albendazole salt on albendazole concentrations in upper small intestine using an in vitro biorelevant gastrointestinal transfer (BioGIT) system

Kourentas, A., Vertzoni, M., Khadra, I., Symillides, M., Clark, H., Halbert, G., Butler, J. & Reppas, C., 30 Sep 2016, In : Journal of Pharmaceutical Sciences. 105, 9, p. 2896-2903 8 p.

Research output: Contribution to journalArticle

Open Access
File
Albendazole
Excipients
Small Intestine
Salts
Solubility

Explosivity: an unusual challenge in drug development

Westwood, N., Londesbrough, D., Ford, S. J. & Halbert, G. W., 4 Apr 2016. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
Pharmaceutical Preparations
Carbon
Drug Stability
Drug Design
Microbial Drug Resistance

Hot-melt extrusion (HME) formulations of Albendazole for increasing dissolution properties

Martinez-Marcos, L., Lamprou, D. & Halbert, G., 7 Apr 2016. 2 p.

Research output: Contribution to conferencePoster

Open Access
File
Albendazole
Pharmaceutical Preparations
Polymers
Pressure
Temperature
Open Access
File
Dosage Forms
Acetaminophen
Injections
Drug Interactions
Powders

Inkjet printing oral dosage forms

Turner, A. J., Halbert, G. W. & Florence, A. J., 5 Sep 2016. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
Printing
Dosage Forms
Solubility
Polymers
Pharmaceutical Preparations

Liquid-filled hard gelatin capsules: excipient/capsule compatibility studies

Kreiner, M., Thayne, N., Harkins, D., Rae, K. & Halbert, G. W., 6 Sep 2016. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
Excipients
Gelatin
Capsules
Pharmaceutical Preparations
Drug Compounding
File
Freeze Drying
Clinical Trials
Boron Neutron Capture Therapy
Temperature
Pharmaceutical Preparations

Online UV imaging of API-excipient mixtures during dissolution

Prasad, E. & Halbert, G. H., 16 Apr 2016. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
Excipients
Pharmaceutical Preparations
methylmethacrylate-methacrylic acid copolymer
carvedilol
5 Citations (Scopus)

Scaling of continuous twin screw wet granulation

Osorio, J. G., Sayin, R., Kalbag, A. V., Litster, J. D., Martinez-Marcos, L., Lamprou, D. A. & Halbert, G. W., 19 Aug 2016, In : AIChE Journal. 12 p.

Research output: Contribution to journalArticle

Open Access
File
Granulation
Porosity
Powders
Granulators
Liquids
3 Citations (Scopus)

The gut in the beaker: missing the surfactants

Wilson, C. G., Halbert, G. W. & Mains, J., 30 Nov 2016, In : International Journal of Pharmaceutics. 514, 1, p. 73-80 8 p.

Research output: Contribution to journalReview article

Open Access
File
Surface-Active Agents
Excipients
Gastrointestinal Agents
Drug Compounding
Deglutition

The influence of non-ionisable excipients on precipitation parameters measured using the CheqSol method

Etherson, K., Halbert, G. & Elliott, M., 30 Sep 2016, In : Journal of Pharmacy and Pharmacology. 68, 9, p. 1131-1142 12 p.

Research output: Contribution to journalArticle

Open Access
File
Excipients
Solubility
Poloxamer
Gliclazide
Atenolol
2015
12 Citations (Scopus)

Investigation of an 11mm diameter twin screw granulator: screw element performance and in-line monitoring via image analysis

Sayin, R., Martinez Marcos, L., Osorio, J. G., Cruise, P., Jones, I., Halbert, G. W., Lamprou, D. A. & Litster, J. D., 2015, In : International Journal of Pharmaceutics. 9 p.

Research output: Contribution to journalArticle

Open Access
File
Particle Size
Drug Industry

Preparation and characterisation of free flowing solid lipid based drug delivery systems using a twin screw extruder

Bowornsaksit, C., Lamprou, D., Halbert, G. & Prasad, E., 29 Sep 2015.

Research output: Contribution to conferencePoster

Open Access
File
Drug Delivery Systems
Lipids
Silicon Dioxide
Powders
Emulsions
2014

Albendazole vs. albendazole sulphate in the fasted upper gastrointestinal lumen based on ex vivo and in vitro data

Kourentas, A., Vertzoni, M., Khadra, I., Halbert, G., Clark, H., Butler, J. & Reppas, C., 2 Nov 2014.

Research output: Contribution to conferencePoster

Albendazole
Sulfates
Solubility
Small Intestine
Salts
Open Access
File
Product Packaging
Gelatin
Blister
Capsules
4 Citations (Scopus)

Determination of excipient based solubility increases using the CheqSol method

Etherson, K., Halbert, G. & Elliott, M., 25 Apr 2014, In : International Journal of Pharmaceutics. 465, 1-2, p. 202-209 8 p.

Research output: Contribution to journalArticle

Excipients
Solubility
Pharmaceutical Preparations
Poloxamer
Gliclazide
138 Citations (Scopus)

Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K-I., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, A., 16 Jun 2014, In : European Journal of Pharmaceutical Sciences. 57, p. 173-199 27 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Pharmaceutical Chemistry
Excipients
Computer Simulation
Oral Administration
28 Citations (Scopus)

GRP receptor imaging of prostate cancer using [(99m)Tc]Demobesin 4: a first-in-man study

Mather, S. J., Nock, B. A., Maina, T., Gibson, V., Ellison, D., Murray, I., Sobnack, R., Colebrook, S., Wan, S., Halbert, G., Szysko, T., Powles, T. & Avril, N., Dec 2014, In : Molecular Imaging and Biology. 16, 6, p. 888-895 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Bombesin Receptors
Radiopharmaceuticals
Single-Photon Emission-Computed Tomography
Pancreas
Open Access
File
Drug Compounding
Rheology
Capsules
Gelatin