Projects per year
Personal profile
Personal Statement
I obtained a pharmacy degree from the University of Strathclyde in 1979 followed by a PhD in Physiochemical Aspects of Anti-Cancer Drug Targeting Systems in 1984. I worked during pre-registration in industrial and hospital pharmacy settings, joined SIPBS as a lecturer in 1984 and was appointed Director of the Formulation Unit in 1992. The Unit's role is to characterise, analyse, formulate and manufacture putative anti-cancer drugs accepted by CRUK's New Agents Committee for use in human clinical trials, where I have now been pharmaceutically responsible for over 20 novel NCE's. Arising from this are research interests, which include medicinal and analytical chemistry, drug physiochemistry, formulation for both small volume and parenteral and oral products and the GMP production of specialist pharmaceutical products for phase l clinical trials. The latter incorporates research areas such as microbiology and lyophilisation. In addition related research is conducted in drug targeting and delivery systems for cancer chemotherapy for example the utilisation of synthetic Low Density Lipoprotein systems. I have over £10 million in personal career grant income and over 150 published papers, conference abstracts and presentations.
Undergraduate teaching is limited due to the nature of the Formulation Unit's activities to introductory and specialist courses associated with the areas above applicable to undergraduate pharmacists. Since 1987 I have been involved in post qualification education teaching for the pharmaceutical industry and initiated and teach on the joint SIPBS-David Begg Associates Qualified Persons training course which has been running since 1991.
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Network
Projects
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Development of a first-in-class IKKalpha inhibitor for the treatment of castrate resistant p
MacKay, S., Halbert, G., Paul, A., Suckling, C. & Watson, D.
1/10/20 → 30/06/22
Project: Research
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Cancer Research UK Formulation Unit for the pharmaceutical and bio-pharmaceutical evaluation of new anti-cancer drugs C149/A28424
Halbert, G., Cygan Barlow, P., Dick, L. & Elliott, M.
1/10/20 → 30/09/21
Project: Research
Research Output
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An interlaboratory investigation of intrinsic dissolution rate determination using surface dissolution
Etherson, K., Dunn, C., Matthews, W., Pamelund, H., Barragat, C., Sanderson, N., Izumi, T., da Costa Mathews, C., Halbert, G., Wilson, C., McAllister, M., Mann, J., Østergaard, J., Butler, J. & Khadra, I., 31 May 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 150, p. 24-32 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)11 Downloads (Pure) -
First-in-human study of AT13148, a dual ROCK-AKT inhibitor in patients with solid tumors
McLeod, R., Kumar, R., Papadatos-Pastos, D., Mateo, J., Brown, J. S., Ingles Garces, A. H., Ruddle, R., Decordova, S., Jueliger, S., Ferraldeschi, R., Maiques, O., Sanz-Moreno, V., Jones, P., Traub, S., Halbert, G., Mellor, S., Swales, K. E., Raynaud, F. I., Garrett, M. D. & Banerji, U., 30 Sep 2020, In: Clinical Cancer Research. 26, p. 4777-4784 8 p.Research output: Contribution to journal › Article › peer-review
Datasets
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Data for: "Manufacturing considerations for the development of lipid nanoparticles using microfluidics"
Roces Rodriguez, C. B. (Creator), Perrie, Y. (Creator) & Halbert, G. (Contributor), University of Strathclyde, 26 Nov 2020
DOI: 10.15129/32db8191-3d6f-4d44-ade0-72c285f82a99
Dataset
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Data for: "Rapid scale-up and production of active-loaded PEGylated liposomes"
Roces Rodriguez, C. B. (Creator), Perrie, Y. (Supervisor), Halbert, G. (Supervisor), Port, E. (Contributor) & Daskalakis, N. (Contributor), University of Strathclyde, 23 Jun 2020
DOI: 10.15129/7aa9989b-3497-4349-80d8-d9678bd230eb
Dataset
Activities
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ToF-SIMS imaging of amorphous solid dispersions: a stability study
Eleonora Paladino (Speaker), Frederik Doerr (Contributor), Iyke I. Onyemelukwe (Contributor), Ian Gilmore (Contributor) & Gavin Halbert (Contributor)
23 Oct 2019Activity: Talk or presentation types › Oral presentation
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3D imaging of controlled-release electrospun material
Eleonora Paladino (Speaker), Ivan Hall Barrientos (Contributor), Frederik Doerr (Contributor), Dimitrios A. Lamprou (Contributor), Melissa Passarelli (Contributor) & Gavin Halbert (Contributor)
12 Sep 2017Activity: Talk or presentation types › Oral presentation
Impacts
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Improved health and survival rates for patients with malignant brain and prostate cancer, and economic benefit from new chemotherapy treatments.
Gavin Halbert (Participant)
Impact: Impact - for External Portal › Economic and commerce, Health and welfare - new products, guidelines and services
File