Fraser Scott

2024

Strathclyde Minor Groove Binders (S-MGBs) with activity against Acanthamoeba castellanii

McGee, L. M. C., Carpinteyro Sanchez, A. G., Perieteanu, M., Eskandari, K., Bian, Y., Mackie, L., Young, L., Beveridge, R., Suckling, C. J., Roberts, C. W. & Scott, F. J., 3 Sept 2024, In: Journal of Antimicrobial Chemotherapy. 79, 9, p. 2251-2258 8 p., dkae221.

Research output: Contribution to journal › Article › peer-review

Open Access

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9 Downloads (Pure)

Introducing graduate employability skills to year 1 chemistry students: reflecting upon impact

Gibson van Mil, L., De Pascale, E., Thomson, P. I. T., Walker, S. & Scott, F. J., 13 Aug 2024, In: Journal of Chemical Education. 101, 8, p. 3003-3012 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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7 Downloads (Pure)

Spectroscopic, biochemical and computational studies of bioactive DNA minor groove binders targeting 5′-WGWWCW-3′ motif

Alniss, H. Y., Kemp, B. M., Holmes, E., Hoffman, J., Ploch, R. M., Ramadan, W. S., Msallam, Y. A., Al-Jubeh, H. M., Madkour, M. M., Celikkaya, B. C., Scott, F. J., El-Awady, R. & Parkinson, J. A., Jul 2024, In: Bioorganic Chemistry. 148, 55 p., 107414.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

14 Downloads (Pure)

Reduce cognitive load with an augmented reality learning environment: discover how to use augmented reality to help students visualise organic mechanisms

Scott, F., 16 May 2024, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Examining the impact of the COVID-19 pandemic on student employability skills: an employer’s perspective

Gibson van Mil, L., De-Pascale, E., Burns, E., Scott, F. J. & Walker, S. E., 23 Apr 2024, In: International Journal of Multidisciplinary: Applied Business and Education Research. 5, 4, p. 1207-1221 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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28 Downloads (Pure)

Understanding how students untangle intermolecular forces: Discover how learners use electronegativity to predict the location of dipole−dipole interactions

Scott, F., 14 Mar 2024, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Boost maths skills to improve chemistry learning: use these evidence-based tips to help your learners get ahead with chemical calculations

Scott, F., 18 Jan 2024, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

MptpB inhibitor improves the action of antibiotics against mycobacterium tuberculosis and nontuberculous mycobacterium avium infections

Rodríguez-Fernández, P., Botella, L., Cavet, J. S., Domínguez, J., Gutierrez, M. G., Suckling, C. J., Scott, F. J. & Tabernero, L., 12 Jan 2024, In: ACS Infectious Diseases. 10, 1, p. 170–183 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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20 Downloads (Pure)

2023

How to banish misconceptions with green chemistry: Evidence-informed tips on how a greener approach can improve problem-solving abilities and address misconceptions

Scott, F., 23 Nov 2023, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

ChemDiverse: a chemistry careers activity showcasing diversity

R. Velasquez, S. T., Nimmo, R., Pookayil, T., Lydon, C., Willison, D. & Scott, F. J., 10 Oct 2023, In: Journal of Chemical Education. 100, 10, p. 3881-3887 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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30 Downloads (Pure)

How to use textbooks effectively: Discover why not all chemistry textbooks are created equal – and what you can do about it

Scott, F., 21 Sept 2023, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Can worm-based products reduce inflammatory burden in cerebral small vessel disease?

Lumbreras Perales, C., Harnett, W., Suckling, C., Scott, F., Van Agtmael, T. & Carswell, H., 4 Sept 2023.

Research output: Contribution to conference › Poster › peer-review

Do parasitic worm products reverse endothelial dysfunction in cerebral small vessel disease?

Lumbreras Perales, C., Suckling, C., Scott, F., Harnett, W., Van Agtmael, T. & Carswell, H., 4 Sept 2023.

Research output: Contribution to conference › Poster › peer-review

The therapeutic potential of drug-like small molecule analogues of the parasitic worm product ES-62 in cerebral small vessel disease

Lumbreras Perales, C., Harnett, W., Suckling, C., Scott, F., Van Agtmael, T. & Carswell, H., 4 Sept 2023.

Research output: Contribution to conference › Poster › peer-review

What's best: Flipped or in-class learning? Discover how one approach can improve student problem-solving skills and performance

Scott, F., 13 Jul 2023, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Leading questions: Help students succeed by steering their questioning in the right direction

Scott, F., 17 May 2023, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Curate video content to capture students' attention

Scott, F., 23 Mar 2023, Education in Chemistry 3 p.

Research output: Contribution to specialist publication › Featured article

Open Access

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24 Downloads (Pure)

Drawing boosts understanding

Scott, F. & Read, D., 14 Feb 2023, Education in Chemistry 4 p.

Research output: Contribution to specialist publication › Featured article

Open Access

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39 Downloads (Pure)

2022

Insights into the spectrum of activity and mechanism of action of MGB-BP-3

Hind, C., Clifford, M., Woolley, C., Harmer, J., McGee, L. M. C., Tyson-Hirst, I., Tait, H. J., Brooke, D. P., Dancer, S. J., Hunter, I. S., Suckling, C. J., Beveridge, R., Parkinson, J. A., Sutton, J. M. & Scott, F. J., 9 Dec 2022, In: ACS Infectious Diseases. 8, 12, p. 2552-2563 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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11 Citations (Scopus)

28 Downloads (Pure)

(Re)framing data

Scott, F., 24 Nov 2022, Education in Chemistry 3 p.

Research output: Contribution to specialist publication › Featured article

Open Access

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21 Downloads (Pure)

Selective anti-Leishmanial Strathclyde minor groove binders using an N-oxide tail group modification

Perieteanu, M. C., McGee, L. M. C., Shaw, C. D., MacMillan, D. S., Khalaf, A. I., Gillingwater, K., Beveridge, R., Carter, K. C., Suckling, C. J. & Scott, F. J., 7 Oct 2022, In: International Journal of Molecular Sciences. 23, 19, 16 p., 11912.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2 Citations (Scopus)

71 Downloads (Pure)

Decision-making factors of female A-level chemistry students when choosing to study a degree in chemistry

Crossdale, R., Scott, F. J. & Sweeney, G., 5 Oct 2022, In: Chemistry Teacher International. 4, 3, p. 231-242 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2 Citations (Scopus)

26 Downloads (Pure)

Ratiometric imaging of minor groove binders in mammalian cells using Raman microscopy

Tentellino, C., Tipping, W. J., McGee, L. M. C., Bain, L. M., Wetherill, C., Laing, S., Tyson-Hirst, I., Suckling, C. J., Beveridge, R., Scott, F. J., Faulds, K. & Graham, D., 26 Sept 2022, In: RSC Chemical Biology. 3, 12, p. 1403-1415 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

3 Citations (Scopus)

55 Downloads (Pure)

Classroom influencer

Scott, F., 8 Sept 2022, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Open Access

File

111 Downloads (Pure)

Exploring the hidden disabilities of mental health in the undergraduate laboratory

De Pascale, E., Scott, F., Thomson, P. & Willison, D., 22 Aug 2022. 17 p.

Research output: Contribution to conference › Poster

Open Access

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34 Downloads (Pure)

Move like a molecule

Scott, F., 7 Jul 2022, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Worm product-based therapies for prevention of bloodbrain barrier breakdown

Lumbreras Perales, C., Suckling, C., Scott, F., Boland, E., Sin, A., Harnett, W., Van Agtmael, T. & Carswell, H., 30 Jun 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 1S, p. 21 1 p., 226.

Research output: Contribution to journal › Conference abstract › peer-review

Improve students' scientific literacy through inquiry

Scott, F., 19 May 2022, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Multitargeted anti-infective drugs: resilience to resistance in the antimicrobial resistance era

Suckling, C. J., Hunter, I. S. & Scott, F. J., 5 May 2022, In: Future Drug Discovery. 4, 1, 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

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45 Downloads (Pure)

Mechanistic reasoning in the chemistry classroom

Scott, F., 3 Feb 2022, Education in Chemistry 3 p.

Research output: Contribution to specialist publication › Featured article

Open Access

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25 Downloads (Pure)

Benefits of desirable difficulties: comparing the influence of mixed practice to that of categorized sets of questions on students’ problem-solving performance in chemistry

Scott, F., 25 Jan 2022, Education in Chemistry, 23, 2, p. 422-435 14 p.

Research output: Contribution to specialist publication › Article

5 Citations (Scopus)

Intranasally administered S-MGB-364 displays antitubercular activity and modulates the host immune response to mycobacterium tuberculosis infection

Kieswetter, N. S., Ozturk, M., Hlaka, L., Chia, J. E., Nichol, R. J. O., Cross, J. M., McGee, L., Tyson-Hirst, I., Beveridge, R., Brombacher, F., Carter, K. C., Suckling, C. J., Scott, F. J. & Guler, R., 25 Jan 2022, In: Journal of Antimicrobial Chemotherapy. 77, 4, p. 1061-1071 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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5 Citations (Scopus)

52 Downloads (Pure)

2021

Erratum: novel minor groove binders cure animal African trypanosomiasis in an in vivo mouse model (J. Med. Chem. (2019) 62 (6) (3021-3035) DOI: 10.1021/acs.jmedchem.8b01847)

Giordani, F., Khalaf, A. I., Gillingwater, K., Munday, J. C., De Koning, H. P., Suckling, C. J., Barrett, M. P. & Scott, F. J., 23 Dec 2021, In: Journal of Medicinal Chemistry. 64, 24, 1 p., 18236.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

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14 Downloads (Pure)

Same molecule, different representations

Scott, F., 30 Nov 2021, Education in Chemistry.

Research output: Contribution to specialist publication › Editorial

The potential for new and resilient anti-cancer drugs based upon minor groove binders for DNA

Scott, F. J. & Suckling, C. J., 29 Nov 2021, In: Medical Research Archives. 9, 11, 18 p., 2592.

Research output: Contribution to journal › Article › peer-review

Open Access

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18 Downloads (Pure)

Correction: Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype

Brooke, D. P., McGee, L. M. C., Giordani, F., Cross, J. M., Khalaf, A. I., Irving, C., Gillingwater, K., Shaw, C. D., Carter, K. C., Barrett, M. P., Suckling, C. J. & Scott, F. J., 26 Nov 2021, (E-pub ahead of print) In: RSC Medicinal Chemistry. 12, 12, p. 2071-2071 1 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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24 Downloads (Pure)

Teaching tips for chemical kinetics

Scott, F., 4 Nov 2021, Education in Chemistry.

Research output: Contribution to specialist publication › Featured article

Students' reflections on an employability skills provision

Scott, F. J. & Willison, D., 14 Sept 2021, In: Journal of Further and Higher Education. 45, 8, p. 1118-1133 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

25 Citations (Scopus)

129 Downloads (Pure)

Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype

Brooke, D. P., McGee, L. M. C., Giordani, F., Cross, J. M., Khalaf, A. I., Irving, C., Gillingwater, K., Shaw, C. D., Carter, K. C., Barrett, M. P., Suckling, C. J. & Scott, F. J., Aug 2021, In: RSC Medicinal Chemistry. 12, 8, p. 1391-1401 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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