1985 …2018
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Research Output 1985 2018

2018

Dataset on the kinetics of the inhibition of PTP1B by the flavonoids and pheophytin A from Allophylus cominia

Semaan, D. G., Igoli, J. O., Young, L., Marrero, E., Gray, A. I. & Rowan, E. G., 1 Apr 2018, In : Data in Brief. 17, p. 401-406 6 p.

Research output: Contribution to journalArticle

Open Access
File
Pheophytins
Flavonoids
alpha-Glucosidases
alpha-Amylases
Enzymes

Glial sulfatides and neuronal complex gangliosides are functionally interdependent in maintaining myelinating axon integrity

McGonigal, R., Barrie, JA., Yao, D., McLaughlin, M., Cunningham, ME., Rowan, EG. & Willison, HJ., 16 Nov 2018, In : Journal of Neuroscience.

Research output: Contribution to journalArticle

Sulfoglycosphingolipids
galactosylceramide sulfotransferase
Gangliosides
Neuroglia
Axons
4 Citations
Open Access
File
Pheophytins
Flavonoids
Adipocytes
Fats
Insulin
Open Access
File
Pheophytins
Moraceae
Ficus
Metabolomics
Chlorophyll

Spontaneous Ca2+ transients in rat pulmonary vein cardiomyocytes are increased in frequency and become more synchronous following electrical stimulation

Henry, A. D., MacQuaide, N., Burton, F. L., Rankin, A. C., Rowan, E. G. & Drummond, R. M., 31 Dec 2018, In : Cell Calcium. 76, p. 36-47 12 p.

Research output: Contribution to journalArticle

Pulmonary Veins
Cardiac Myocytes
Electric Stimulation
Sarcolemma
Ryanodine Receptor Calcium Release Channel
2017
4 Citations
Open Access
File
Ficus
ovarian neoplasms
Ovarian Neoplasms
Cells
Complex Mixtures
7 Citations

Cisplatin induced arrhythmia; electrolyte imbalance or disturbance of the SA node?

Oun, R. & Rowan, E., 6 Jun 2017, In : European Journal of Pharmacology. 4 p.

Research output: Contribution to journalArticle

Open Access
File
Cisplatin
Electrolytes
Cardiac Arrhythmias
Poisons
Bradycardia
3 Citations

Individual variability of venom from the European adder (Vipera berus berus) from one locality in Eastern Hungary

Malina, T., Krecsák, L., Westerström, A., Szemán-Nagy, G., Gyémánt, G., M-Hamvas, M., Rowan, E. G., Harvey, A. L., Warrell, D. A., Pál, B., Rusznák, Z. & Vasas, G., 1 Sep 2017, In : Toxicon. 135, p. 59-70 12 p.

Research output: Contribution to journalArticle

Open Access
File
Hungary
Adders
Venoms
Viperidae
Phospholipases A2
6 Citations
Open Access
File
Pheophytins
alpha-Glucosidases
alpha-Amylases
Flavonoids
Enzymes
2016
1 Citations
Open Access
File
Ritodrine
Metabolomics
Myometrium
Oxytocin
Adrenergic beta-Agonists
2015
4 Citations

The neuromuscular activity of Bothriopsis bilineata smaragdina (forest viper) venom and its toxin Bbil-TX (Asp49 phospholipase A2) on isolated mouse nerve-muscle preparations

Floriano, R. S., Rocha, T., Carregari, V. C., Marangoni, S., da Cruz-Höfling, M. A., Hyslop, S., Rodrigues-Simioni, L. & Rowan, E. G., 15 Mar 2015, In : Toxicon. 96, p. 24-37 14 p.

Research output: Contribution to journalArticle

Viper Venoms
Neuromuscular Junction
Phospholipases A2
Venoms
Muscle
8 Citations

Viperatoxin-II: a novel viper venom protein as an effective bactericidal agent

Samy, R. P., Stiles, B. G., Chinnathambi, A., Zayed, M. E., Alharbi, S. A., Franco, O. L., Rowan, E. G., Kumar, A. P., Lim, L. H. K. & Sethi, G., 23 Oct 2015, In : FEBS Open Bio. 5, 1, p. 928-941 14 p.

Research output: Contribution to journalArticle

Open Access
File
Viper Venoms
Burkholderia pseudomallei
Proteus vulgaris
Staphylococcus aureus
Snake Venoms
2014
2 Citations

Animal toxins and their advantages in biotechnology and pharmacology

Da Silva, S. L., Rowan, E. G., Albericio, F., Stábeli, R. G., Calderon, L. A. & Soares, A. M., 22 May 2014, In : BioMed Research International. 2014, 2 p., 951561.

Research output: Contribution to journalArticle

Open Access
File
Venoms
Biotechnology
Animals
Pharmacology
Biodiversity
16 Citations

Neuronal expression of GalNAc transferase is sufficient to prevent the age-related neurodegenerative phenotype of complex ganglioside-deficient mice

Yao, D., McGonigal, R., Barrie, J. A., Cappell, J., Cunningham, M. E., Meehan, G. R., Fewou, S. N., Edgar, J. M., Rowan, E., Ohmi, Y., Furukawa, K., Furukawa, K., Brophy, P. J. & Willison, H. J., 15 Jan 2014, In : Journal of Neuroscience. 34, 3, p. 880-891 12 p.

Research output: Contribution to journalArticle

Gangliosides
Neuroglia
Phenotype
Myelin Sheath
Nervous System
46 Citations

The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles

Oun, R., Floriano, R. S., Isaacs, L., Rowan, E. G. & Wheate, N. J., 1 Nov 2014, In : Toxicology Research. 3, 6, p. 447-455 9 p.

Research output: Contribution to journalArticle

Open Access
File
Drug delivery
Pharmaceutical Preparations
Cisplatin
Toxicity
Platinum
17 Citations

Wound healing activity and mechanisms of action of an antibacterial protein from the venom of the eastern diamondback rattlesnake (Crotalus adamanteus)

Samy, R. P., Kandasamy, M., Gopalakrishnakone, P., Stiles, B. G., Rowan, E. G., Becker, D., Shanmugam, M. K., Sethi, G. & Chow, V. T. K., 14 Feb 2014, In : PLOS One. 9, 2, 16 p., e80199.

Research output: Contribution to journalArticle

Open Access
File
Crotalus adamanteus
antibacterial proteins
Crotalus
Venoms
venoms
2013
5 Citations

Effects of Odontobuthus doriae scorpion venom on mouse sciatic nerve

Vatanpour, H., Jalali, A., Rowan, E. & Rahim, F., 28 Feb 2013, In : Iranian Journal of Pharmaceutical Research. 12, Supplement, p. 145-151 7 p.

Research output: Contribution to journalArticle

Scorpion Venoms
Venoms
Sciatic Nerve
Action Potentials
Temperature
4 Citations

Neurotoxic phospholipase A2 toxicity model: an insight from mammalian cells

Vardjan, N., Mattiazzi, M., Rowan, E. G., Križaj, I., Petrovič, U. & Petan, T., 9 Apr 2013, In : Communicative and Integrative Biology. 6, 3, 3 p., e23600.

Research output: Contribution to journalArticle

Open Access
File
phospholipase A2
Phospholipases A2
endocytosis
Secretory Phospholipase A2
Endocytosis
4 Citations
Bungarotoxins
Phospholipases
Neuromuscular Junction
Neurotoxins
Snake Venoms
13 Citations

The leaves of Ficus exasperata Vahl (Moraceae) generates uterine active chemical constituents

Bafor, E. E., Lim, C. V., Rowan, E. G. & Edrada-Ebel, R., 13 Feb 2013, In : Journal of Ethnopharmacology. 145, 3, p. 803–812 10 p.

Research output: Contribution to journalArticle

Moraceae
Ficus
Phytochemicals
Pharmacology
12 Citations

Varicella-zoster viruses associated with post-herpetic neuralgia induce sodium current density increases in the ND7-23 Nav-1.8 neuroblastoma cell line

Kennedy, P. G. E., Montague, P., Scott, F., Grinfeld, E., Ashrafi, G. H., Breuer, J. & Rowan, E., 31 Jan 2013, In : PLOS One. 8, 1, 9 p., e51570.

Research output: Contribution to journalArticle

Open Access
File
Human herpesvirus 3
Human Herpesvirus 3
Neuralgia
Neuroblastoma
Viruses
2012
18 Citations

Snake venom phospholipases A(2): a novel tool against bacterial diseases

Samy, R. P., Gopalakrishnakone, P., Stiles, B. G., Girish, K. S., Swamy, S. N., Hemshekhar, M., Tan, K. S., Rowan, E. G., Sethi, G. & Chow, V. T. K., 2012, In : Current Medicinal Chemistry. 19, 36, p. 6150-6162 13 p.

Research output: Contribution to journalArticle

Snake Venoms
Phospholipases A
Membranes
Peptides
Cysteine

Systematic isolation and metabolomic analysis of uterine active compounds from the leaf extracts of Ficus exasperata (Moraceae)

Bafor, E., Lim, C. V., Rowan, E. & Edrada-Ebel, R., Jul 2012, p. PG10. 1 p.

Research output: Contribution to conferencePoster

Moraceae
Ficus
Metabolomics
Plant Leaves
Flavonoids
2011

Classic toxins

Rowan, E. G., Oct 2011, In : Toxicon. 58, 5, p. 453-453 1 p.

Research output: Contribution to journalEditorial

Sorbus
13 Citations

Serum TNF-alpha levels reflect the clinical severity of envenomation following a Hemiscorpius lepturus sting

Jalali, A., Pipelzadeh, M. H., Taraz, M., Khodadadi, A., Makvandi, M. & Rowan, E. G., Mar 2011, In : EUROPEAN CYTOKINE NETWORK. 22, 1, p. 5-10 6 p.

Research output: Contribution to journalArticle

Bites and Stings
Tumor Necrosis Factor-alpha
Scorpions
Passive Immunization
Serum
7 Citations

Snake toxins from mamba venoms: unique tools for the physiologist

Rowan, E. G. & Harvey, A. L., 2011, In : Acta Chimica Slovenica. 58, 4, p. 689-692 4 p.

Research output: Contribution to journalArticle

Venoms
Peptides
Snake Venoms
Serine Proteinase Inhibitors
Nicotinic Receptors
Open Access
File
Suramin
Neuromuscular Junction
Phospholipases A
Neurotoxins
Bungarotoxins

TTX, cations and spider venom modify avian muscle tone in vitro

Herzig, V., Hodgson, W. C. & Rowan, E. G., 2011, In : Journal of Venom Research . 2, p. 1-5 5 p.

Research output: Contribution to journalArticle

Spider Venoms
Cations
Venoms
Muscles
Tubocurarine
2010
83 Citations

Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice

McGonigal, R., Rowan, E. G., Greenshields, K. N., Halstead, S., Humphreys, P. D., Rother, R. P., Furukawa, K. & Willison, H. J., 2010, In : Brain. 133, 7, p. 1944-1960 17 p.

Research output: Contribution to journalArticle

Open Access
File
Nodal Protein
Ranvier's Nodes
Guillain-Barre Syndrome
Calpain
Anti-Idiotypic Antibodies
8 Citations

Spontaneous and electrically evoked Ca2+ transients in cardiomyocytes of the rat pulmonary vein

Logantha, S. J. R. J., Cruickshank, S. F., Rowan, E. G. & Drummond, R. M., Aug 2010, In : Cell Calcium. 48, 2-3, p. 150-160 11 p.

Research output: Contribution to journalArticle

Pulmonary Veins
Cardiac Myocytes
Ryanodine
Inositol 1,4,5-Trisphosphate Receptors
Optical Imaging
2009
4 Citations

Transcriptome profiling of neuronal model cell PC12 from rat pheochromocytoma

Saminathan, R., Pachiappan, A., Feng, L., Rowan, E. G. & Gopalakrishnakone, P., Jun 2009, In : Cellular and Molecular Neurobiology. 29, 4, p. 533-548 16 p.

Research output: Contribution to journalArticle

PC12 Cells
Pheochromocytoma
Gene Expression Profiling
Nervous System Diseases
Transcriptome
2008
29 Citations

A presynaptically toxic secreted phospholipase A2 is internalized into motoneuron-like cells where it is rapidly translocated into the cytosol

Praznikar, Z. J., Kovacic, L., Rowan, E. G., Romih, R., Rusmini, P., Poletti, A., Krizaj, I. & Pungercar, J., 2008, In : BBA - Biochimica et Biophysica Acta. 1783, 6, p. 1129-1139 11 p.

Research output: Contribution to journalArticle

Secretory Phospholipase A2
Poisons
Motor Neurons
Cytosol
Cross-Linking Reagents
56 Citations

A review of epidemiological, clinical and in vitro physiological studies of envenomation by the scorpion Hemiscorpius lepturus (Hemiscorpiidae) in Iran

Jalali, A., Pipelzadeh, M. H., Sayedian, R. & Rowan, E. G., 2008, In : Toxicon. 55, 2-3, p. 173-9 164 p.

Research output: Contribution to journalArticle

Scorpions
Venoms
Iran
Ethics
In Vitro Techniques
13 Citations

Neurotoxicity of ammodytoxin A in the envenoming bites of vipera ammodytes ammodytes

Logonder, U., Krizaj, I., Rowan, E. G. & Harris, J. B., Oct 2008, In : Journal of Neuropathology and Experimental Neurology. 67, 10, p. 1011-1019 9 p.

Research output: Contribution to journalArticle

Neuromuscular Junction
Bites and Stings
Muscles
Snake Venoms
Synaptic Vesicles
2007
Drug and Narcotic Control
Pharmacology
18 Citations

The effect of the venom of the yellow Iranian scorpion Odontobuthus doriae on skeletal muscle preparations in vitro

Jalali, A., Vatanpour, H., Hosseininasab, Z., Rowan, E. G. & Harvey, A. L., 2007, In : Toxicon. 50, 8, p. 1019-1026 8 p.

Research output: Contribution to journalArticle

Scorpions
Venoms
Muscle
Skeletal Muscle
Scorpion Venoms
20 Citations

The neuromuscular activity of paradoxin: a presynaptic neurotoxin from the venom of the inland taipan (Oxyuranus microlepidotus)

Hodgson, W. C., Dal Belo, C. A. & Rowan, E. G., 2007, In : Neuropharmacology. 52, 5, p. 1229-36 1193 p.

Research output: Contribution to journalArticle

Venoms
Neurotoxins
Diaphragm
paradoxin
Phrenic Nerve
2006
16 Citations

Binding to the high-affinity M-type receptor for secreted phospholipases A(2) is not obligatory for the presynaptic neurotoxicity of ammodytoxin A

Prijatelj, P., Vardjan, N., Rowan, E. G., Krizaj, I. & Pungercar, J., 2006, In : Biochimie. 88, 10, p. 1425-1433 8 p.

Research output: Contribution to journalArticle

Phospholipases A
Fusion reactions
Cell membranes
Cell Membrane
C-Type Lectins
2005
69 Citations

A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel alpha-subunits

McCartney, C. E., McClafferty, H., Huibant, J-M., Rowan, E. G., Shipston, M. J. & Rowe, I. C. M., 2005, In : Proceedings of the National Academy of Sciences . 102, 49, p. 17870-17876 6 p.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Cysteine
Exons
RNA Precursors
Alternative Splicing
24 Citations

Pharmacological and structural characterization of a novel phospholipase A2 from Micrurus dumerilii carinicauda venom

Belo, C. A. D., Leite, G. B., Toyama, M. H., Marangoni, S., Corrado, A. P., Fontana, M. D., Southan, A., Rowan, E. G., Hyslop, S. & Rodrigues-Simioni, L., 2005, In : Toxicon. 46, 7, p. 736-50 686 p.

Research output: Contribution to journalArticle

Elapidae
Neuromuscular Blockade
Phospholipases A2
Venoms
Diaphragms
2003
88 Citations

Crossing the pain barrier: P2 receptors as targets for novel analgesics

Kennedy, C., Assis, T. S., Currie, A. J. & Rowan, E. G., 2003, In : Journal of Physiology. 553, 3, p. 683-694 11 p.

Research output: Contribution to journalArticle

Chronic Pain
Analgesics
Purinergic P2X3 Receptors
Pain
Sensory Receptor Cells
19 Citations
Muscarinic M5 Receptors
Muscarinic M3 Receptors
Muscarinic M1 Receptors
Elapidae
Venoms
2002
4 Citations
Colubridae
Phospholipases A
Venoms
Potassium
Muscle

Characterisation of p2x receptors in rat dorsal root ganglion sensory neurons

Currie, A. J., Rowan, E. G. & Kennedy, C., Dec 2002, In : Lasers in Medical Science. 137, Proceedings Supplement, p. 102P-102P

Research output: Contribution to journalArticle

Spinal Ganglia
Sensory Receptor Cells

Muscarinic receptors and calcium signalling in rabbit isolated pulmonary artery smooth muscle cells

O'Neill, G. T., Rowan, E. G. & Gurney, A. M., Dec 2002, In : British Journal of Pharmacology. 137, Suppl., p. 24P-24P

Research output: Contribution to journalArticle

Calcium Signaling
Muscarinic Receptors
Pulmonary Artery
Smooth Muscle Myocytes
Rabbits

The effects of hypoxia and anoxia on the activity of neuronal large conductance calcium-activated potassium (bkca) channels

McCartney, C. E., Rowan, E. G. & Rowe, I. C. M., Dec 2002, In : British Journal of Pharmacology. 137, Suppl., p. 41P-41P

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Research
Genes
Hypoxia
2001
137 Citations

Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal

O'Hanlon, G. M., Plomp, J. J., Chakrabarti, M., Morrison, I., Wagner, E. R., Goodyear, C. S., Yin, X., Trapp, B. D., Conner, J., Molenaar, P. C., Stewart, S., Rowan, E. G. & Willison, H. J., 2001, In : Brain. 124, 5, p. 893-906 13 p.

Research output: Contribution to journalArticle

Anti-Idiotypic Antibodies
Miller Fisher Syndrome
Motor Endplate
Ophthalmoplegia
Neuromuscular Blockade
8 Citations

Effects of brucine, a plant alkaloid, on M(1) muscarinic receptors and alpha(1)-adrenoceptors in the rabbit vas deferens preparation

Bradley, K., Rowan, E. & Harvey, A. L., Apr 2001, In : Toxicon. 39, 4, p. 581-587 7 p.

Research output: Contribution to journalArticle

Vas Deferens
Muscarinic Receptors
Alkaloids
Adrenergic Receptors
Rabbits
14 Citations
Snake Venoms
Phospholipases
Neuromuscular Junction
Neurotoxins
Voltage-Gated Potassium Channels