• United Kingdom

Accepting PhD Students

20012019
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Research Output 2001 2019

2019

Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives on breast cancer cell growth and invasion

Brown, I., Lee, J., Sneddon, A. A., Cascio, M. G., Pertwee, R. G., Wahle, K. W. J., Rotondo, D. & Heys, S. D., 16 Oct 2019, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. p. 1-10 10 p., 102024 .

Research output: Contribution to journalArticle

Endocannabinoids
Ethanolamine
Cell growth
Breast Neoplasms
Derivatives
1 Downloads (Pure)

Predictive binding affinity of plant-derived natural products towards the protein kinase G enzyme of Mycobacterium tuberculosis (MtPknG)

M. Qasaymeh, R., Rotondo, D., Oosthuizen, C. B., Lall, N. & Seidel, V., 6 Nov 2019, In : Plants. 8, 11, 14 p., 477.

Research output: Contribution to journalArticle

Open Access
File
Biological Products
Pelargonium
Mycobacterium tuberculosis
Ligands
Tuberculosis
2018
7 Downloads (Pure)
Open Access
File
Receptors, Prostaglandin E, EP4 Subtype
Prostaglandin Receptors
Dinoprostone
Tumor Necrosis Factor-alpha
Cytokines
2015
31 Downloads (Pure)

Blood immunoglobulins, complement and TNF receptor following minimally invasive surgery in patients undergoing pulmonary lobectomy

Leaver, H. A., Craig, S. R., Rotondo, D. & Walker, W. S., 5 Jan 2015, In : Current Metabolomics. 2, 3, p. 196-203 8 p.

Research output: Contribution to journalArticle

Open Access
File
Complement Receptors
Minimally Invasive Surgical Procedures
Tumor Necrosis Factor Receptors
Immunoglobulins
Acute-Phase Proteins
5 Citations (Scopus)
56 Downloads (Pure)

Regulation of lipid metabolism by microRNAs

Tate, R., Rotondo, D. & Davidson, J., 10 Jun 2015, In : Current Opinion in Lipidology. 26, 3, p. 243-244 2 p.

Research output: Contribution to journalEditorial

Open Access
File
2014
2 Downloads (Pure)

Cellular and humoral responses following minimally invasive surgery: role of reactive oxygen species

Leaver, H. A., Rotondo, D. & Walker, W. S., Oct 2014, In : Current Metabolomics. 2, 4, p. 223-232 10 p.

Research output: Contribution to journalArticle

Open Access
File
Minimally Invasive Surgical Procedures
Surgery
Reactive Oxygen Species
Oxidative stress
Leukocytes
2013
57 Citations (Scopus)

Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators

Brown, I., Cascio, M. G., Rotondo, D., Pertwee, R. G., Heys, S. D. & Wahle, K. W. J., Jan 2013, In : Progress in Lipid Research. 52, 1, p. 80-109 30 p.

Research output: Contribution to journalArticle

Endocannabinoids
Cannabinoids
Cell death
Modulators
Cell Death
10 Citations (Scopus)
Tumor Necrosis Factor-alpha
Dinoprostone
Prostaglandins
Ethanolamine
Cyclic AMP
6 Citations (Scopus)
Eicosapentaenoic Acid
Up-Regulation
Dinoprostone
Poly I-C
Interleukin-1
1 Citation (Scopus)

Genetics and molecular biology: the role of retinoic acid receptor genes in acute promyelocytic leukemia

Davidson, J., Tate, R. & Rotondo, D., 14 Aug 2013, In : Current Opinion in Lipidology. 24, 4, p. 364-365 2 p.

Research output: Contribution to journalComment/debate

Acute Promyelocytic Leukemia
Retinoic Acid Receptors
Molecular biology
Tretinoin
Molecular Biology
2012

Genetics and molecular biology: the role of nucleotide oligomerization domain-like genes in insulin resistance

Rotondo, D. & Davidson, J., 1 Oct 2012, Current Opinion in Lipidology, 23, 5, p. 501-502 2 p.

Research output: Contribution to specialist publicationEditorial

Insulin Resistance
Molecular Biology
Nucleotides
Fats
Obesity
27 Citations (Scopus)

Therapeutic implications of disorders of cell death signalling: membranes, micro-environment, and eicosanoid and docosanoid metabolism

Davidson, J., Rotondo, D., Rizzo, M. & Leaver, A., 6 Jun 2012, In : British Journal of Pharmacology. 166, 4, p. 1193-1210 18 p.

Research output: Contribution to journalLiterature review

Eicosanoids
Unsaturated Fatty Acids
Cell Death
Membranes
Pathologic Processes
2011
7 Citations (Scopus)

Genetics and molecular biology: fatty acid metabolism in cancer cell survival; carnitine palmitoyltransferase-1 as a critical anticancer target

Rotondo, D. & Davidson, J., Oct 2011, Current Opinion in Lipidology, 22, 5, p. 428-429 2 p.

Research output: Contribution to specialist publicationEditorial

Carnitine O-Palmitoyltransferase
Molecular Biology
Cell Survival
Fatty Acids
Carnitine
2010
2 Citations (Scopus)
20 Downloads (Pure)

Identification of dyslipidemia genes: genetics and molecular biology

Rotondo, D. & Davidson, J., Dec 2010, Current Opinion in Lipidology, 21, 6, p. 548-549 2 p.

Research output: Contribution to specialist publicationEditorial

Open Access
File
Dyslipidemias
Molecular Biology
Alleles
Single Nucleotide Polymorphism
Obesity
76 Citations (Scopus)

Plant phenolics in the prevention and treatment of cancer

Wahle, K. W. J., Brown, I., Rotondo, D. & Heys, S. D., 16 Dec 2010, Bio-Farms for Nutraceuticals: Functional Food and Safety Control by Biosensors . Giardi, MT., Rea, G. & Berra, B. (eds.). New York, Vol. 698. p. 36-51 16 p. (Advances in Experimental Medicine and Biology; vol. 698).

Research output: Chapter in Book/Report/Conference proceedingChapter

Neoplasms
Diet
Conjugated Linoleic Acids
Food and Beverages
Adhesiveness
2008
8 Citations (Scopus)
Androsterone
Prostaglandin D2
Dinoprostone
Modulation
Prostaglandins
2004
81 Citations (Scopus)

Prostaglandin e2 is a potent regulator of interleukin-12- and interleukin-18-induced natural killer cell interferon y synthesis

Walker, W. & Rotondo, D., 2004, In : Immunology. 111, 3, p. 298-305 8 p.

Research output: Contribution to journalArticle

Interleukin-18
Interleukin-12
Dinoprostone
Natural Killer Cells
Interferons
2003
30 Citations (Scopus)

Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release

Cameron, P., Smith, S. J., Giembycz, M. A., Rotondo, D. & Plevin, R. J., 2003, In : British Journal of Pharmacology. 140, 7, p. 1320-1330 10 p.

Research output: Contribution to journalArticle

Shiga Toxins
Mitogen-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
Monocytes
Apoptosis
2002
11 Citations (Scopus)

Essential role for verotoxin in sustained stress-activated protein kinase and nuclear factor kappa b signaling, stimulated by escherichia coli o157:H7 in vero cells

Cameron, P., Bingham, D., Paul, A., Pavelka, M., Cameron, S., Rotondo, D. & Plevin, R. J., 2002, In : Infection and Immunity. 70, 10, p. 5370-5380 11 p.

Research output: Contribution to journalArticle

Shiga Toxins
Vero Cells
Escherichia coli O157
Heat-Shock Proteins
Protein Kinases
2001
57 Citations (Scopus)

Cytokines and cytokine inducers stimulate prostaglandin E2 entry into the brain

Davidson, J., Abul, H. T., Milton, A. S. & Rotondo, D., Jul 2001, In : Pflugers Archiv - European Journal of Physiology. 442, 4, p. 526-533 7 p.

Research output: Contribution to journalArticle

Cerebrospinal fluid
Dinoprostone
Brain
Cerebrospinal Fluid
Cytokines