Christopher McCormick

Dr

  • United Kingdom

Accepting PhD Students

20072023
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Research Output 2007 2020

2020
2 Downloads (Pure)

Development of a bioactive polymeric drug eluting coronary stent coating using electrospraying

McKittrick, C. M., Cardona, M. J., Black, R. A. & McCormick, C., 1 Jan 2020, In : Annals of Biomedical Engineering . 48, 1, p. 271-281 11 p.

Research output: Contribution to journalArticle

Open Access
File
Drug-Eluting Stents
Stents
Coatings
Polymers
Equipment and Supplies
2019

Asymptotic analysis of drug dissolution in two layers having widely differing diffusivities

Vynnycky, M., McKee, S., Meere, M., McCormick, C. & McGinty, S., 9 Jan 2019, (Accepted/In press) In : IMA Journal of Applied Mathematics. 22 p.

Research output: Contribution to journalArticle

Open Access
File
Asymptotic analysis
Dissolution
Diffusivity
Asymptotic Analysis
Drugs
1 Citation (Scopus)

Combining mathematical modelling with in vitro experiments to predict in vivo drug-eluting stent performance

McKittrick, C. M., McKee, S., Kennedy, S., Oldroyd, K., Wheel, M., Pontrelli, G., Dixon, S., McGinty, S. & McCormick, C., 10 Jun 2019, In : Journal of Controlled Release. 303, p. 151-161 11 p.

Research output: Contribution to journalArticle

Drug-Eluting Stents
Stents
Sirolimus
Theoretical Models
Pharmaceutical Preparations

Release and activity of the broad spectrum antibiotic Rifampicin from biodegradable polymer PLGA

McCormick, C., 28 Feb 2019, (Accepted/In press).

Research output: Contribution to conferenceSpeech

2018
10 Citations (Scopus)
48 Downloads (Pure)

3D biofabrication for tubular tissue engineering

Holland, I., Logan, J., Shi, J., McCormick, C., Liu, D. & Shu, W., 23 May 2018, In : Bio-Design and Manufacturing. 12 p.

Research output: Contribution to journalArticle

Open Access
File
Tissue Engineering
Technology
Therapeutics
Growth
Research

A local drug delivery technology to prevent implant infections

Fraser, J., MacLean, M. & McCormick, C., 6 Sep 2018.

Research output: Contribution to conferencePoster

Biodegradable polymers
Biofilms
Antibiotics
Drug delivery
Acids
Biodegradable polymers
Biofilms
Drug delivery
Antibiotics
Glass
3 Citations (Scopus)
42 Downloads (Pure)

Modelling drug release from polymer-free coronary stents with microporous surfaces

Vo, T. T. N., Morgan, S., McCormick, C., McGinty, S., McKee, S. & Meere, M., 15 Jun 2018, In : International Journal of Pharmaceutics. 544, 2, p. 392-401 10 p.

Research output: Contribution to journalArticle

Open Access
File
Stents
Polymers
Drug-Eluting Stents
Theoretical Models
Arteries
7 Downloads (Pure)

On the influence of non-uniform binding site density in determining arterial drug distribution following stent-based delivery

Escuer, J., Scullion, B., McCormick, C. & McGinty, S., 8 Jul 2018. 2 p.

Research output: Contribution to conferenceAbstract

Open Access
File
Sirolimus
Stents
Binding Sites
Paclitaxel
Pharmaceutical Preparations
18 Downloads (Pure)

Release and activity of rifampicin from biodegradable polymer formulations

Fraser, J., Muangsaen, H., MacLean, M. & McCormick, C., 4 Sep 2018. 1 p.

Research output: Contribution to conferenceAbstract

Open Access
File
Biodegradable polymers
Rifampin
Polymers
Equipment and Supplies
Antibiotics
3 Citations (Scopus)
17 Downloads (Pure)
Open Access
File
Acoustic impedance
Stents
Endothelial cells
impedance
Electric Impedance
2017
14 Downloads (Pure)

Combining mathematical modelling with in-vitro experiments to predict in-vivo drug-eluting stent kinetics

McGinty, S., McCormick, C., McKittrick, C. M., Kennedy, S., Oldroyd, K. G., Wheel, M., Scullion, B., Pontrelli, G., McKee, S., Nithiarasu, P. (ed.) & Robertson, A. M. (ed.), 10 Apr 2017, 5th International Conference on Computational and Mathematical Biomedical Engineering (CMBE2017). Swansea UK, p. 1011-1014 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

Open Access
File
Stents
Kinetics
Acrylics
Experiments
Mathematical models
Mitochondrial Dynamics
Mitochondria
Endothelial cells
Modulation
Endothelial Cells

Overview of cardiovascular stent designs

McCormick, C., 22 Sep 2017, Functionalised Cardiovascular Stents. Wall, J. G., Podbielska, H. & Wawrzynska, M. (eds.). San Diego, CA., p. 3-26 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Stents
Percutaneous Coronary Intervention
Drug-Eluting Stents
Balloon Angioplasty
Coronary Artery Bypass

Polymer-free drug-eluting stents

McCormick, C., 22 Sep 2017, Functionalised Cardiovascular Stents. Wall, J. G., Podbielska, H. & Wawrzyńska, M. (eds.). San Diego, CA., p. 57-74 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Drug-Eluting Stents
Stents
Polymers
Equipment and Supplies
Risk Reduction Behavior
13 Downloads (Pure)
Open Access
File
Coronary Restenosis
Dielectric Spectroscopy
Electric Impedance
Gap Junctions
Stents
2016
66 Downloads (Pure)

A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery

McCormick, C., Jones, R. L., Wadsworth, R. M., Mullen, A. B. & Kennedy, S., 13 Jun 2016, (Accepted/In press) In : Pharmacology and Pharmacy. 12 p.

Research output: Contribution to journalArticle

Open Access
File
Neointima
Iliac Artery
Stents
Polymers
Rabbits
1 Citation (Scopus)
47 Downloads (Pure)
Open Access
File

Development and characterisation of novel polypyrrole coatings for coronary stents

Morgan, S., Black, R. & McCormick, C., 31 May 2016.

Research output: Contribution to conferencePoster

Inhibition of mitochondrial fission as a potential therapeutic target for vascular disease?

Kaloya, S., McCarron, J., Chalmers, S. & McCormick, C., 2016, (Unpublished).

Research output: Contribution to conferencePoster

Mitochondrial Dynamics
Vascular Diseases
Stents
Endothelial Cells
Cell Proliferation

Post-stenting arterial healing: an in vitro impedance study

Holland, I., McCormick, C. & Connolly, P., 19 Jun 2016.

Research output: Contribution to conferencePoster

Stents
Endothelial cells
Muscle
Monolayers
Cells
2015

Alginate scaffolds for cardiac tissue regeneration

Galluzzo, A., Gourlay, T. & McCormick, C., 14 Jul 2015.

Research output: Contribution to conferencePoster

10 Downloads (Pure)

Assessment of drug incorporation and release from a novel coronary stent coating

McKittrick, C. M., Dixon, S. & McCormick, C., 30 Aug 2015.

Research output: Contribution to conferencePoster

Open Access
File
Stents
Drug-Eluting Stents
Coatings
Cytostatic Agents
Sirolimus

A system for characterisation of smooth muscle and endothelial cells in real time

Holland, I., McCormick, C. & Connolly, P., 14 Jul 2015.

Research output: Contribution to conferencePoster

A system for real time characterisation of smooth muscle cells

Holland, I., Connolly, P. & McCormick, C., 7 Feb 2015.

Research output: Contribution to conferencePoster

Can anisotropy enhance the spatial uniformity of drug distribution in biological tissue? 

McGinty, S., Wheel, M., McKee, S., McCormick, C., McKittrick, C., Kennedy, S. & Oldroyd, K. G., 1 Jul 2015, 4th International Conference on Computational & Mathematical Biomedical Engineering. Nithiarasu, P. & Budyn, E. (eds.). Swansea, p. 194-197 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

Anisotropy
Tissue
Drug delivery
Stents
Kinetics

Conducting polymer coatings for improved coronary stent performance

Morgan, S., Black, R. & McCormick, C., 14 Jul 2015.

Research output: Contribution to conferencePoster

10 Citations (Scopus)
416 Downloads (Pure)
Open Access
File
Stent
Stents
Anisotropy
Uniformity
Drugs

Investigation into bioactive surfaces for improved coronary stent performance

Morgan, S., Black, R. & McCormick, C., 30 Aug 2015.

Research output: Contribution to conferencePoster

Investigation into surface topgraphy of coronary stents

Morgan, S., Black, R. A. & McCormick, C., 7 Feb 2015.

Research output: Contribution to conferencePoster

15 Citations (Scopus)
117 Downloads (Pure)

Modelling the impact of atherosclerosis on drug release and distribution from coronary stents

McKittrick, C. M., Kennedy, S., Oldroyd, K. G., McGinty, S. & McCormick, C., 18 Sep 2015, In : Annals of Biomedical Engineering . 44, 2, p. 477-487 11 p.

Research output: Contribution to journalArticle

Open Access
File
Stents
Drug-Eluting Stents
Atherosclerosis
Pharmaceutical Preparations
Physical Phenomena
16 Citations (Scopus)
100 Downloads (Pure)
Open Access
File
Stent
Drug-Eluting Stents
Stents
Parameter estimation
Parameter Estimation
18 Citations (Scopus)
119 Downloads (Pure)

Some design considerations for polymer-free drug-eluting stents: a mathematical approach

McGinty, S., Vo, T. T. N., Meere, M., McKee, S. & McCormick, C., 2015, In : Acta Biomaterialia.

Research output: Contribution to journalArticle

Open Access
File
Drug-Eluting Stents
Stents
Polymers
Pharmaceutical Preparations
Drug Liberation
2013
9 Citations (Scopus)
300 Downloads (Pure)

Modeling arterial wall drug concentrations following the insertion of a drug-eluting stent

McGinty, S., McKee, S., Wadsworth, R. M. & McCormick, C., 1 Dec 2013, In : SIAM Journal on Applied Mathematics. 73, 6, p. 2004-2028 25 p.

Research output: Contribution to journalArticle

Open Access
File
Stent
Stents
Insertion
Drugs
Tissue
20 Citations (Scopus)
55 Downloads (Pure)

Modelling arterial wall drug concentrations following the insertion of a drug-eluting stent

McGinty, S., McKee, S., Wadsworth, R. & McCormick, C., 2013, In : SIAM Journal on Applied Mathematics . 73, 6, p. 2004-2028 25 p.

Research output: Contribution to journalArticle

Open Access
File
Stent
Drug-Eluting Stents
Stents
Insertion
Drugs

Optimising coronary stent drug release profiles

McCormick, C., 25 Jul 2013.

Research output: Contribution to conferenceAbstract

97 Downloads (Pure)

Simulating drug-eluting stents: progress made and the way forward

McGinty, S., McCormick, C., McKee, S., Wheel, M., Kennedy, S. & Oldroyd, K. G., Jul 2013, p. 664-671. 8 p.

Research output: Contribution to conferencePaper

Open Access
File
Stent
Drugs
Restenosis
Thrombosis
Coronary Artery Disease
10 Citations (Scopus)

Succinobucol-eluting stents increase neointimal thickening and peri-strut inflammation in a porcine coronary model

Watt, J., Kennedy, S., McCormick, C., Agbani, E. O., McPhaden, A., Mullen, A., Czudaj, P., Behnisch, B., Wadsworth, R. M. & Oldroyd, K. G., Mar 2013, In : Catheterization and Cardiovascular Interventions. 81, 4, p. 698 - 708 11 p.

Research output: Contribution to journalArticle

Stents
Swine
Inflammation
Metals
Sirolimus
2012
19 Citations (Scopus)

Towards blood free measurement of glucose and potassium in humans using reverse iontophoresis

McCormick, C., Heath, D. & Connolly, P., 20 May 2012, In : Sensors and Actuators B: Chemical. 166-167, p. 593-600 8 p.

Research output: Contribution to journalArticle

glucose
blood
Glucose
Potassium
potassium
2011

Minimally invasive sensing

McCormick, C., Heath, D. & Connolly, P., 2011, Biosensors - emerging materials and applications. Serra, P. A. (ed.).

Research output: Chapter in Book/Report/Conference proceedingChapter

2010
11 Citations (Scopus)

Activation of prostanoid EP receptors by prostacyclin analogues in the rabbit iliac artery: implications for anti-restenotic potential?

McCormick, C., Jones, R. L., Kennedy, S. & Wadsworth, R. M., 1 Sep 2010, In : European Journal of Pharmacology. 641, 2-3, p. 160-167 7 p.

Research output: Contribution to journalArticle

Epoprostenol Receptors
Iliac Artery
Prostaglandins
Receptors, Prostaglandin E, EP3 Subtype
Rabbits
34 Citations (Scopus)

Modelling drug-eluting stents

McGinty, S., Mckee, S., Wadsworth, R. & McCormick, C., 22 Apr 2010, In : Mathematical Medicine and Biology. 28, 1, p. 1-29 30 p.

Research output: Contribution to journalArticle

Stent
Drug-Eluting Stents
Stents
Drugs
Polymers
2007
15 Citations (Scopus)

Prostacyclin analogues: the next drug-eluting stent?

McCormick, C., Wadsworth, R. M., Jones, R. L. & Kennedy, S., Nov 2007, In : Biochemical Society Transactions. 35, Part 5, p. 910-911 2 p.

Research output: Contribution to journalArticle

Drug-Eluting Stents
Stents
Epoprostenol
Pharmaceutical Preparations
Endothelium
3 Citations (Scopus)

The search for endothelium friendly stents

McCormick, C., 1 May 2007, In : Medical Device Technology. 18, 3, p. 30, 32-33 3 p.

Research output: Contribution to journalArticle

Endothelium
Stents
Thrombosis
Drug-Eluting Stents
Pharmaceutical Preparations