Chris John Price, FRSC CChem

Dr

  • United Kingdom

Accepting PhD Students

1987 …2023
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Research Output 1987 2020

2020

Continuous isolation of active pharmaceutical ingredients

Price, C. J., Barton, A. & Coleman, S., 21 Feb 2020, The Handbook of Continuous Crystallization. Yazdanpanah, N. & Nagy, Z. (eds.). 1st ed. [S.I.]

Research output: Chapter in Book/Report/Conference proceedingChapter

Nucleation control in continuous crystallization

Sefcik, J., Ter Horst, J., McGinty, J. & Price, C. J., 21 Feb 2020, The Handbook of Continuous Crystallization. Yazdanpanah, N. & Nagy, Z. (eds.). 1st ed. [S.I.]

Research output: Chapter in Book/Report/Conference proceedingChapter

Developing a method to determine the flux of material arriving and leaving a crystal at equilibrium

Nguyen, T. T. H., Vesga, J., Parkinson, J. & Price, C. J., 9 Jul 2019, p. 74. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
crystals
surface layers
2 Citations (Scopus)

Development of a novel continuous filtration unit for pharmaceutical process development and manufacturing

Ottoboni, S., Price, C. J., Steven, C., Meehan, E., Barton, A., Firth, P., Mitchell, A. & Tahir, F., 31 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 372-381 10 p.

Research output: Contribution to journalArticle

Open Access
File
Drug products
Pharmaceutical Preparations
Washing
Processing
Practice Guidelines
1 Citation (Scopus)

Unconventional ultra scale-down techniques for active pharmaceutical ingredient filtration and size reduction

Ojo, E. O., Rayat, A., Price, C. J., Brown, C. J., Hoare, M., Johnston, A. & Florence, A. J., 11 Jul 2019, p. 88. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
Drug products
Crystals
Pharmaceutical Preparations
Pore size
Particle size analysis
Crystallization
Washing
Acetaminophen
Pharmaceutical Preparations
Impurities
2018

Elucidating the mechanism of paracetamol sonocrystallization for product purity enhancement

Forbes, C., Nguyen, T. T. H., O'Leary, R. L. & Price, C. J., 27 Feb 2018, (Accepted/In press) In : Proceedings of Meetings on Acoustics. 32, 5 p., ICU2017 - 287.

Research output: Contribution to journalArticle

Open Access
File
Acetaminophen
Cavitation
Bubbles (in fluids)
Ultrasonics
Alcohols
13 Citations (Scopus)

Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations

Brown, C. J., McGlone, T., Yerdelen, S., Srirambhatla, V., Mabbott, F., Gurung, R., Briuglia, M. L., Ahmed, B., Polyzois, H., McGinty, J., Perciballi, F., Fysikopoulos, D., Macfhionnghaile, P., Siddique, H., Raval, V., Harrington, T. S., Vassileiou, A., Robertson, M., Prasad, E., Johnston, A. & 9 othersJohnston, B., Nordon, A., Srai, J., Halbert, G., Ter Horst, J. H., Price, C. J., Rielly, C. D., Sefcik, J. & Florence, A. J., 1 Jun 2018, In : Molecular Systems Design & Engineering. 2018, 3, p. 518-549 32 p.

Research output: Contribution to journalArticle

Open Access
File
Workflow
Crystallization
Drug products
Cooling
Pharmaceutical Preparations
5 Citations (Scopus)
Open Access
File
Secondary Ion Mass Spectrometry
Surface Properties
Acetaminophen
Secondary ion mass spectrometry
secondary ion mass spectrometry
2017

Addressing the challenges of continuous filtration, washing and drying

Price, C. J. & Ottoboni, S., 23 Feb 2017.

Research output: Contribution to conferenceSpeech

Washing
Drying
Application programming interfaces (API)
Solubility
Crystals

Continuous pharmaceutical crystallization from solution

Price, C. J., 28 Jul 2017, Engineering Crystallography: From Molecule to Crystal to Functional Form. Roberts, K. J., Docherty, R. & Tamura, R. (eds.). 1st ed. Dordrecht, The Netherlands: Springer, p. 315-329 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmaceutical Solutions
Crystallization
Drug products
Drug Industry
Pharmaceutical Preparations
7 Citations (Scopus)

The effect of ultrasound on the crystallisation of paracetamol in the presence of structurally similar impurities

Nguyen, T. T. H., Khan, A., Bruce, L. M., Forbes, C., O'Leary, R. & Price, C. J., 30 Sep 2017, In : Crystals. 24 p.

Research output: Contribution to journalArticle

Open Access
File
Acetaminophen
Crystallization
Ultrasonics
Impurities
crystallization
2016

Development of a novel continuous filtration unit for pharmaceutical process development and manufacturing: a case study using paracetamol

Ottoboni, S., Price, C. J., Steven, C., Meehan, E., Barton, A. & Mitchell, A., 13 Oct 2016. 18 p.

Research output: Contribution to conferenceProceeding

Acetaminophen
Drug products
Equipment and Supplies
Drug Industry
Pharmaceutical Preparations
Secondary Ion Mass Spectrometry
Surface Properties
Acetaminophen
Secondary ion mass spectrometry
Crystallization
Acetaminophen
Impurities
Crystals
Growth
Supersaturation
2015
16 Citations (Scopus)

Adipic acid primary nucleation kinetics from probability distributions in droplet-based systems under stagnant and flow conditions

Rossi, D., Gavriilidis, A., Kuhn, S., Candel, M. A., Jones, A. G., Price, C. & Mazzei, L., 1 Apr 2015, In : Crystal Growth and Design. 15, 4, p. 1784-1791 8 p.

Research output: Contribution to journalArticle

Open Access
File
Probability distributions
Nucleation
nucleation
acids
Kinetics

Particles & opportunities

Price, C., 2015, (Unpublished).

Research output: Contribution to conferenceKeynote

Drug Industry
2012

Developing pharmaceutical continuous crystallization processes

Price, C. J., 2012.

Research output: Contribution to conferencePaper

2011
2004
148 Citations (Scopus)

Impact of molecular speciation on crystal nucleation in polymorphic systems: the conundrum of gamma glycine and molecular 'self poisoning'

Towler, C. S., Davey, R. J., Lancaster, R. W. & Price, C. J., 20 Oct 2004, In : Journal of the American Chemical Society. 126, 41, p. 13347-13353 7 p.

Research output: Contribution to journalArticle

Glycine
Poisoning
Amino acids
Nucleation
Crystals
2000

Finding novel solutions to common crystallization problems

Price, C. J., 2000.

Research output: Contribution to conferencePaper

1998
73 Citations (Scopus)

The use of ultrasound in industrial chemical synthesis and crystallization. 1. Applications to synthetic chemistry

Cains, P. W., Martin, P. D. & Price, C. J., 1 Jan 1998, In : Organic Process Research and Development. 2, 1, p. 34-48 15 p.

Research output: Contribution to journalArticle

Industrial chemicals
Crystallization
Chemical Phenomena
Ultrasonics
chemistry
1997
46 Citations (Scopus)

Take some solid steps to improve crystallization

Price, C. J., 1 Sep 1997, In : Chemical Engineering Progress. 93, 9, 10 p.

Research output: Contribution to journalArticle

Crystallization
Chemical operations
Industry

Ultrasound - the key to better crystals for the pharmaceutical industry

Price, C. J., 1 Sep 1997, In : Pharmaceutical Technology Europe. 9, p. 78-86 9 p.

Research output: Contribution to journalArticle

1995

Sonocrystallization - designing better crystals for the pharmaceutical industry

Price, C. J. & Martin, P. D., 1995.

Research output: Contribution to conferencePaper

1993

Characterising crystal habit and perfection: a calibration Strategy

Price, C. J., 1 Nov 1993, Analyical Proceedings. 11 ed. Vol. 30. p. 449-450 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

2 Citations (Scopus)

Characterizing the effect of growth conditions and crystal habit on the distribution of imperfections amongst populations of crystals

Price, C. J., 1 Mar 1993, In : Journal of Crystal Growth. 128, 1-4, p. 1277–1281 5 p.

Research output: Contribution to journalConference Contribution

habits
Defects
Crystals
defects
Copper Sulfate
3 Citations (Scopus)

Crystallization kinetics: the role of particle characterisation

Price, C. J., 1 Nov 1993, In : Analytical Proceedings. 30, 11, p. 451-452 2 p.

Research output: Contribution to journalArticle

Crystallization kinetics
Specifications
Crystals
Crystallization
Single crystals

Power ultrasound - a new tool for controlling crystallization IChemE

Price, C. J. & Martin, P. D., 1993.

Research output: Contribution to conferencePaper