• United Kingdom

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20032021
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Personal profile

Research Interests

  1. Environmental Microbiology
  2. Eco-toxicology
  3. Soil & Water Quality
  4. Antibiotic resistance in the environment

Microorganisms are omnipresent and capable of impacting the entire biosphere. They, especially the bacteria, are highly diverse in terms of structure and function, and they can play a major role in cycling of nutrients, remediation of contamination, and public health. My research interest involves the integration of state-of-the-art microbiological measurement technologies and ecological principles into the realm of environmental protection and sustainability.

Some on-going projects: 

Team DAGGAR - Dangerous and Growing Globally, Antimicrobial Resistance. 

Work related to antimicrobial resistance evolved from pharmaceutical eco-toxicology with the development of microbial-community endpoints. This work resulted in international exposure and award-winning publications. International collaborations include researchers and government/policy agencies in Australia, UK, USA, Canada, Cuba, Denmark and The Netherlands. Research focus has been to quantitatively measure resistance genes and antibiotics in the environment; it extends previous qualitative observations to a predictive level aimed at solving practical problems.  The investigations of PEC (pollutants of emerging concern) continue, as it remains a contemporary international problem.

Team ARMOR – Antimicrobial Resistance May Offer Resilience? (stability and resilience of microbial communities and performance during pollution stress). 

Microbial community dynamics are examined in response to contaminant exposure in engineered bioreactors. The research endeavours to find processes that are ecologically resilient and economically robust to avoid major investment in a new (or upgraded) treatment process as new regulations emerge.

GR-AMS - Greco-Roman Antimicrobial Minerals.  Multi-disciplinary, collaborative project.

Teaching Interests

Management roles:

Courses taught:

  • Environmental Engineering (CL328)
  • Water & Wastewater Treatment Design (CL447 + CL978)
  • Principles of Environmental Microbiology (CL430 + CL948)
  • Pollution and the Rehabilitation of Degraded Ecosystems (EV908)
  • MSc Projects in Environmental Engineering (CL944)
  • Independent Study in Collaboration with Industry (CL973, contributor)

Awards:

  • 2018 - Teaching Excellence Awards, nominated
  • 2016 - Teaching Excellence Awards, shortlisted Best in Faculty.
  • 2015 - Teaching Excellence Awards, shortlisted Best in Faculty.
  • 2015 - Fellow of the Higher Education Academy (FHEA)
  • 2014 - Teaching Excellence Awards, shortlisted Overall Best Supportive Teacher

International courses

  • Microbiology for Engineers, Gdansk University of Technology (Poland, 2018)
  • Microbiology for Engineers, Indian Institute of Technology-Bombay (India, 2017)
  • Restoration of contaminated land, Gdansk University of Technology (Poland, 2015)
  • Ecotoxicology, Gdansk University of Technology (Poland, 2014)

Academic / Professional qualifications

Work Experience

Additional Qualifications:

  • 2015 - Fellow of the Higher Education Academy (FHEA) 

Expertise & Capabilities

Research themes:

  • Antibiotic resistance in the environment
  • Antimicrobial resistance
  • Susceptibility assays
  • Biological indicators of environmental pollution
  • Microbiological community stability in engineered and natural systems
  • Eco-toxicology, bioremediation
  • Outdoor, microcosm/mesocosm experimental systems

Routine research services

  • DNA/RNA analyses
  • PCR (polymerase chain reaction)
  • Genetic probe design (primer design)
  • Community analysis (sequencing, DGGE)
  • Biological assessments of soil, sediment and water
  • Molecular and microbiological techniques
  • Phytoplankton, algae
  • Bacteria
  • Micro-invertebrates
  • Water quality monitoring
  • Soil quality determinations
  • Wastewater analysis

Advance Statistics

  • Descriptor / inferential 
  • Multi-parametric analyses
  • Non-parametric analyses
  • Community analyses

Personal Statement

Dr. Knapp is Course Coordinator of MSc Environmental Engineering and active researcher in the "Water, Environment, Sustainability and Public Health" (WESP) research centre.

Think you can live without microbes?  Wanna take that challenge?

Microorganisms are omnipresent and capable of impacting the entire biosphere. They, especially the bacteria, are highly diverse in terms of structure and function, and they can play a major role in cycling of nutrients, remediation of contamination, and public health. Unfortunately, many people often overlook the ecological interactions within the microbial communities that support the process. Understanding these interactions require knowledge of the distribution and abundance of organisms and their interactions in an environmental setting. Further, it requires analytical tools to examine microbial organisms in an effective and timely fashion. Fortunately, high throughput culture-independent molecular methods are allowing researchers to quantitatively monitor these interactions. My research interest involves the integration of state-of-the-art microbiological measurement technologies and ecological principles into the realm of environmental protection and sustainability.

Education/Academic qualification

Doctor of Philosophy, University of Kansas

Master of Science, University of Kansas

Bachelor of Science, University of Kansas

External positions

Research Associate - EU Marie Curie funded, Newcastle University

1 Oct 200631 Jan 2009

Research Associate, University of Kansas

1 Sep 200230 Sep 2006

Keywords

  • wastewater treatment
  • bioremediation
  • pollution control
  • pharmaceutical contamination
  • lagoon
  • constructed wetland
  • microbiology
  • molecular ecology
  • microbial ecology
  • limnology
  • water quality
  • molecular biology
  • DNA analysis
  • RNA analysis
  • genomic
  • bioinformatics

Fingerprint Dive into the research topics where Charles Knapp is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Genes Chemical Compounds
antibiotic resistance Earth & Environmental Sciences
Anti-Bacterial Agents Chemical Compounds
Microbial Drug Resistance Medicine & Life Sciences
gene Earth & Environmental Sciences
Probiotics Medicine & Life Sciences
antibiotics Earth & Environmental Sciences
bacterium Earth & Environmental Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2009 2021

Research Output 2003 2019

4 Citations (Scopus)

Can the legacy of industrial pollution influence antimicrobial resistance in estuarine sediments?

Rodgers, K., McLellan, I., Peshkur, T., Williams, R., Tonner, R., Hursthouse, A. S., Knapp, C. W. & Henriquez, F. L., 30 Jun 2019, In : Environmental Chemistry Letters. 17, 2, p. 595-607 13 p.

Research output: Contribution to journalArticle

Open Access
File
estuarine sediment
antibiotics
Sediments
Pollution
Anti-Bacterial Agents

Effect of β-glycosidase supplementation on vinasse saccharification and L-lactic acid fermentation

Cao, Y., Wang, J., Wang, Q., Liu, J., Liu, T., Knapp, C. W. & Wang, Y., 7 Jan 2019, In : BioResources. 14, 1, p. 1379-1389 11 p.

Research output: Contribution to journalArticle

Open Access
File
Saccharification
Glycoside Hydrolases
Lactic acid
Fermentation
fermentation

Thesis

Nitrogen and phosphorous removal from groundwater using waste materials

Author: Gkiouzepas, S., 1 Feb 2015

Supervisor: Kalin, R. (Supervisor) & Knapp, C. (Supervisor)

Student thesis: Doctoral Thesis

The role of water distribution systems in the enrichment of antimicrobial resistance

Author: Khan, S., 1 Oct 2016

Supervisor: Knapp, C. (Supervisor) & Beattie, T. (Supervisor)

Student thesis: Doctoral Thesis

Activities 2008 2019

Iqaluit, Nunavut - sampling expedition

Charles Knapp (Participant), Mark L. Hanson (Advisor)
6 Aug 201913 Aug 2019

Activity: Other activity typesOther

Antimicrobial resistance: what does the environment have to say

Charles Knapp (Speaker)
5 Feb 2019

Activity: Talk or presentation typesInvited talk