19952019

Research output per year

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Research Output

2019
1 Citation (Scopus)

P2Y1 and P2Y12 receptor heterodimerisation: from recombinant systems to native detection

Safar, M. A., Wood, R., Cunningham, M. R. & Kennedy, C., 1 Aug 2019, In : British Journal of Pharmacology. 176, 16, p. 3049 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
File
12 Downloads (Pure)
2018

Comparison of signalling mechanisms underlying UTP-evoked vasoconstriction of rat pulmonary and tail arteries

Tengah, A., Syed, N-H., Abdul Talip, S. T., Bujang, S. N. B. & Kennedy, C., 15 Oct 2018, In : European Journal of Pharmacology. 837, p. 45-52 8 p.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

Heterodimerisation of purinergic GPCRs

Safar, M. A. A., Wood, R. A. (ed.), Cunningham, M. R. & Kennedy, C. (ed.), 15 Nov 2018.

Research output: Contribution to conferencePoster

12 Downloads (Pure)
Open Access
File
8 Citations (Scopus)
10 Downloads (Pure)
2017

P2Y11 receptors: properties, distribution and functions

Kennedy, C., 26 Jul 2017, (Accepted/In press) In : Advances in Experimental Medicine and Biology.

Research output: Contribution to journalLiterature review

Open Access
File
75 Downloads (Pure)
2015

ATP as a cotransmitter in the autonomic nervous system

Kennedy, C., Sep 2015, In : Autonomic Neuroscience: Basic and Clinical . 191, p. 2-15 14 p.

Research output: Contribution to journalLiterature review

Open Access
File
21 Citations (Scopus)
108 Downloads (Pure)
2014

UTP is not a biased agonist at human P2Y11 receptors

Morrow, G. B., Nicholas, R. A. & Kennedy, C., Dec 2014, In : Purinergic Signalling . 10, 4, p. 581-585 5 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
69 Downloads (Pure)
2013

P2X and P2Y nucleotide receptors as targets in cardiovascular disease

Kennedy, C., Chootip, K., Mitchell, C., Syed, N-I-H. & Tengah, A., Mar 2013, In : Future Medicinal Chemistry. 5, 4, p. 431-439 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The Concise Guide to PHARMACOLOGY 2013/14: overview

Alexander, S. P. H., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., McGrath, J. C., Catterall, W. A., Spedding, M., Peters, J. A., Harmar, A. J., Abul-Hasn, N., Anderson, C. M., Anderson, C. M. H., Araiksinen, M. S., Arita, M., Arthofer, E., Barker, E. L., Barratt, C., Barnes, N. M., Bathgate, R. & 31 others, Beart, P. M., Belelli, D., Bennett, A. J., Birdsall, N. J. M., Boison, D., Bonner, T. I., Brailsford, L., Bröer, S., Brown, P., Calo, G., Carter, W. G., Catterall, W. A., Chan, S. L. F., Chao, M. V., Chiang, N., Christopoulos, A., Chun, J. J., Cidlowski, J., Clapham, D. E., Cockcroft, S., Connor, M. A., Cox, H. M., Cuthbert, A., Dautzenberg, F. M., Davenport, A. P., Dawson, P. A., Jones, R. L., Kennedy, C., Pyne, N. J., Pyne, S. & CGTP Collaborators, Dec 2013, In : British Journal of Pharmacology. 170, 8, p. 1449-58 10 p.

Research output: Contribution to journalSpecial issue

133 Citations (Scopus)

The importance of drug discovery for treatment of cardiovascular diseases.

Kennedy, C., Mar 2013, In : Future Medicinal Chemistry. 5, 4, p. 355-357 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2012

A Ca2+-dependent chloride current and Ca2+ influx via Cav1.2 ion channels play major roles in P2Y receptor-mediated pulmonary vasoconstriction

Mitchell, C., Syed, N-I-H., Gurney, A. & Kennedy, C., Jun 2012, In : British Journal of Pharmacology. 166, 4, p. 1503-1512 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

ATP inhibits Ins(1,4,5)P3-evoked Ca2+ release in smooth muscle via P2Y1 receptors

MacMillan, D., Kennedy, C. & McCarron, J., 1 Nov 2012, In : Journal of Cell Science. 125, 21, p. 5151-5158 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Identification of contractile P2Y1, P2Y6 and P2Y12 receptors in rat intrapulmonary artery using selective ligands

Mitchell, C., Syed, N-I-H., Tengah, A., Gurney, A. & Kennedy, C., Dec 2012, In : Journal of Pharmacology and Experimental Therapeutics. 343, 3, p. 755-762 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2010

Characterisation of P2X receptors expressed in rat pulmonary arteries

Syed, N-I-H., Tengah, A., Paul, A. & Kennedy, C., 15 Dec 2010, In : European Journal of Pharmacology. 649, 1-3, p. 342-348 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Two-pore potassium ion channels are inhibited by both Gq/11- and Gi-coupled P2Y receptors

Shakya-Shrestha, S., Parmar, M., Kennedy, C. & Bushell, T., Apr 2010, In : Molecular and Cellular Neuroscience. 43, 4, p. 363-369 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2009

Highlights in purinergic signalling

Kennedy, C., 2009, In : Purinergic Signalling. 5, 3, p. 265-7 3 p.

Research output: Contribution to journalArticle

2008

Ca2+-signalling pathways involved in P2X receptor-induced contractions of rat small pulmonary artery

Kennedy, C. & Syed, N-H., May 2008, In : Purinergic Signalling. 4, S1, p. S201-S201

Research output: Contribution to journalConference Contribution

Ca2+-signalling pathways involved in P2X receptor-induced contractions of rat small pulmonary artery

Syed, N. H. & Kennedy, C., Aug 2008, In : Fundamental and Clinical Pharmacology . 22, S2, p. 76-76

Research output: Contribution to journalConference Contribution

Characterisation of the effects of the phospholipase c inhibitor U73122 on P2Y receptor-mediated contractions of the rat isolated pulmonary artery

Kennedy, C. & Tengah, A., May 2008, In : Purinergic Signalling. 4, Supplement 1, p. S80-S81

Research output: Contribution to journalConference Contribution

Is there a role for P2 receptors other than the P2X1 subtype in parasympathetic cotransmission in the urinary bladder?

Kennedy, C., May 2008, In : Purinergic Signalling. 4, p. S200-S200

Research output: Contribution to journalConference Contribution

P2X3 receptors and sensory transduction

Kennedy, C., 2008, Sensing with Ion Channels. Berlin, Germany: Springer, Vol. 11. p. 247-266 19 p. (Springer Series in Biophysics).

Research output: Chapter in Book/Report/Conference proceedingChapter

The role of ca2+sensitisation in p2x receptor-induced contractions of rat small pulmonary artery

Kennedy, C. & Syed, N. I. H., May 2008, In : Purinergic Signalling. 4, p. S200-S201

Research output: Contribution to journalConference Contribution

The role of ca2+ sensitisation in p2x receptor-induced contractions of rat small pulmonary artery

Syed, N. H. & Kennedy, C., Aug 2008, In : Fundamental and Clinical Pharmacology . 22, p. 69-79 11 p.

Research output: Contribution to journalConference Contribution

18 Citations (Scopus)
2007

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder

Kennedy, C., Tasker, P., Gallagher, G. & Westfall, T., 2007, In : Journal of Neuroscience. 27, p. 845-851 7 p.

Research output: Contribution to journalArticle

Open Access
File
33 Citations (Scopus)
43 Downloads (Pure)
2006

International Union of Pharmacology LVIII: Update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

Abbracchio, M. P., Burnstock, G., Boeynaems, J., Barnard, E. A., Boyer, J. L., Kennedy, C., Knight, G. E., Fumagalli, M., Gachet, C., Jacobson, K. A. & Weisman, G. A., Sep 2006, In : Pharmacological Reviews. 58, 3, p. 281-341 60 p.

Research output: Contribution to journalArticle

910 Citations (Scopus)
2005

Multiple P2Y receptors couple to calcium-dependent, chloride channels in smooth muscle cells of the rat pulmonary artery

Chootip, K., Gurney, A. M. & Kennedy, C., 26 Oct 2005, In : Respiratory Research. 6, 124.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
76 Downloads (Pure)
2003

Crossing the pain barrier: P2 receptors as targets for novel analgesics

Kennedy, C., Assis, T. S., Currie, A. J. & Rowan, E. G., 2003, In : Journal of Physiology. 553, 3, p. 683-694 11 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)
2002

Characterisation of p2x receptors in rat dorsal root ganglion sensory neurons

Currie, A. J., Rowan, E. G. & Kennedy, C., Dec 2002, In : Lasers in Medical Science. 137, Proceedings Supplement, p. 102P-102P

Research output: Contribution to journalArticle

Regional variation in p2 receptor expression in the rat pulmonary arterial circulation

Chootip, K., Ness, K. F., Wang, Y., Gurney, A. M. & Kennedy, C., 2002, In : British Journal of Pharmacology. 137, 5, p. 637-646 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2001

Differential coupling of the human P2Y11 receptor to phospholipase C and adenylyl cyclase

Qi, A-D., Kennedy, C., Harden, T. K. & Nicholas, R. A., Jan 2001, In : British Journal of Pharmacology. 132, 1, p. 318-326 8 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2000
Open Access
24 Citations (Scopus)
1998

Pharmacological properties of p2x(3)-receptors present in neurones of the rat dorsal root ganglia

Rae, M. G., Rowan, E. G. & Kennedy, C., May 1998, In : Lasers in Medical Science. 124, 1, p. 176-180 4 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)
1996

Characterisation of p-2x-purinoceptors in neurones of the neonatal rat dorsal root ganglia

Rae, M. G., Rowan, E. G. & Kennedy, C., Dec 1996, In : British Journal of Pharmacology. 119, p. P369-P369

Research output: Contribution to journalArticle

Characterization of a P-2x-purinoceptor in cultured neurones of the rat dorsal root ganglia

Robertson, S. J., Rae, M. G., Rowan, E. G. & Kennedy, C., Jun 1996, In : British Journal of Pharmacology. 118, 4, p. 951-956 5 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)
1995

Characterization of the electrophysiological actions of P-2-purinoceptor agonists in cultured neurons in the rat

Robertson, S. J., Rowan, E. R. & Kennedy, C., Oct 1995, In : British Journal of Pharmacology. 116, Supplement, p. P54-P54

Research output: Contribution to journalArticle