Blair Johnston, Assistant Director CMAC National Facility

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• Active

  PharmaCrystNet: Improving the Predictive Capabilities of Crystallisation Models in

  Brown, C. (Principal Investigator), Dolean Maini, V. (Co-investigator) & Johnston, B. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/09/24 → 31/08/25

  Project: Research

• SHARPEN: SHARing data to accelerate Pharmaceutical manufacturing Efficiency across trusted Networks

  Johnston, B. (Principal Investigator), Florence, A. (Co-investigator) & Markl, D. (Co-investigator)

  Innovate UK

  1/08/24 → 31/01/26

  Project: Research

• DTP 2224 University of Strathclyde | Robertson, Jason

  Johnston, B. (Principal Investigator), Markl, D. (Co-investigator) & Robertson, J. (Research Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/10/23 → 1/10/29

  Project: Research Studentship - Internally Allocated

• DTP 2224 University of Strathclyde | Clark, Connor

  Florence, A. (Principal Investigator), Johnston, B. (Co-investigator) & Clark, C. (Research Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/10/23 → 1/04/27

  Project: Research Studentship - Internally Allocated

• Industrial CASE Account - University of Strathclyde 2022 | Osman, Amal

  Johnston, B. (Principal Investigator), Florence, A. (Co-investigator) & Osman, A. (Research Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/12/22 → 1/12/26

  Project: Research Studentship Case - Internally allocated

• DTP 2224 University of Strathclyde | Tsioutsios, Alexandros

  Markl, D. (Principal Investigator), Johnston, B. (Co-investigator) & Tsioutsios, A. (Research Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/10/22 → 1/04/26

  Project: Research Studentship - Internally Allocated

• Dialling up 3D Printing Performance for On Demand Manufacturing (Programme Grant)

  Florence, A. (Principal Investigator) & Johnston, B. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/10/22 → 30/09/27

  Project: Research

• International Collaboration for Digital Design and Manufacture of Amorphous Pharmaceuticals

  Florence, A. (Principal Investigator), Brown, C. (Co-investigator), Johnston, B. (Co-investigator), Markl, D. (Co-investigator) & Robertson, J. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/02/22 → 30/04/26

  Project: Research

• Made Smarter Innovation: Digital Medicines Manufacturing Research Centre (DM2)

  Florence, A. (Principal Investigator), Johnston, B. (Co-investigator), Markl, D. (Co-investigator) & Pierce, G. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/09/21 → 28/02/25

  Project: Research

  • Dosage Forms 100%
  • Tablet 38%
  • Size of Particle 33%
  • Shapes of Particle 33%
  • Density 33%

• CMMI-EPSRC - Right First Time Manufacture of Pharmaceuticals (RiFTMaP)

  Markl, D. (Principal Investigator) & Johnston, B. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/09/21 → 31/08/25

  Project: Research

  • Tablet 100%
  • Drug 40%
  • Particle-Size Distribution 20%
• Finished

  A Regulatory Science Network for the Digital Transformation of Medicines Development and Manufacturing (10113547)

  Markl, D. (Principal Investigator), Florence, A. (Co-investigator) & Johnston, B. (Co-investigator)

  Innovate UK

  1/03/24 → 31/08/24

  Project: Knowledge Exchange

• Digital Design Accelerator Platform to Connect Active Material Design to Product Performance (Manufacturing Made Smarter)

  Florence, A. (Principal Investigator) & Johnston, B. (Co-investigator)

  Innovate UK

  1/03/20 → 31/08/22

  Project: Research

• Investigating the biomolecular complexity of drug-induced cardiotoxicity by fingerprinting single cell and cardiac spheroid mass spectral information using Time-of-flight Secondary Ion Mass Spectrometry (TOF-SIMS)

  Cunningham, M. R. (Principal Investigator), Veerman, B. (Post Grad Student), Johnston, B. (Co-investigator) & Currie, S. (Co-investigator)

  1/02/19 → 28/02/22

  Project: Research Studentship - Internally Allocated

  • Cardiotoxicity 100%
  • Tumor Microenvironment 50%
  • Malignant Neoplasm 50%

• Accelerated Discovery and Development of New Medicines: Prosperity Partnership for a Healthier Nation

  Kerr, W. (Principal Investigator), Brown, C. (Co-investigator), Florence, A. (Co-investigator), Jamieson, C. (Co-investigator), Johnston, B. (Co-investigator), Murphy, J. (Co-investigator), Palmer, D. (Co-investigator) & Tomkinson, N. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/01/19 → 30/09/24

  Project: Research

  • Synthesis (Chemical) 100%
  • Chemical Reaction 63%
  • Bromodomain 53%
  • Application 46%
  • Palladium 45%

• ARTICULAR: ARtificial inTelligence for Integrated ICT-enabled pharmaceUticaL mAnufactuRing

  Johnston, B. (Principal Investigator), Brown, C. (Co-investigator) & Florence, A. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/07/18 → 31/12/22

  Project: Research

  • Crystallization 100%
  • Pharmaceutical Manufacturing 75%
  • Solvent 75%
  • Isolation Method 75%
  • Biological Product 30%

• Predicting the Propensity of Solvate and Hydrate Formation in Small Molecule Crystal Structures

  Johnston, B. (Principal Investigator)

  Cambridge Crystallographic Data Centre (CCDC) (The)

  1/01/18 → 30/06/21

  Project: Research - Studentship

• Future Continuous Manufacturing and Advanced Crystallisation Research Hub (CMAC Hub)

  Florence, A. (Principal Investigator), Brown, C. (Co-investigator), Halbert, G. (Co-investigator), Johnston, B. (Co-investigator), Markl, D. (Co-investigator), Nordon, A. (Co-investigator), Price, C. J. (Co-investigator), Sefcik, J. (Co-investigator) & Ter Horst, J. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/01/17 → 30/09/24

  Project: Research

  • Tablet 100%
  • Crystallization 74%
  • Crystal 71%
  • Solvent 69%
  • Mefenamic Acid 55%

• Small molecule regulators of the p53 interacting kinases

  Tomkinson, N. (Principal Investigator) & Johnston, B. (Co-investigator)

  Cancer Research UK CRUK

  1/10/15 → 30/09/19

  Project: Research - Studentship

• Tracing the fate of nanomedicines in the tumour microenvironment (MC Career Integration) | Totten, John

  Seib, P. (Principal Investigator), Johnston, B. (Co-investigator) & Totten, J. (Research Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/10/15 → 4/06/19

  Project: Research - Internally Allocated

  • Anticarcinogen 100%
  • Drug Delivery 100%
  • Reprogramming 100%
  • Drug Release 75%
  • Drug 25%

• Generating and Interrogating Crystallographic Data to Predict Solid-State Properties

  Kennedy, A. (Principal Investigator), Silva de Moraes, L. (Post Grad Student) & Johnston, B. (Co-investigator)

  11/05/15 → 1/05/19

  Project: Research - Studentship

• International Institute for Advanced Pharmaceutical Manufacturing (I2APM) (SAVI)

  Johnston, B. (Principal Investigator), Florence, A. (Co-investigator) & Sefcik, J. (Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/02/15 → 31/07/18

  Project: Research

  • Manufacturing 100%
  • Activity 66%
  • Specific Industry 66%
  • Drugs 66%
  • Research 66%

• Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Wareham, Bruce James

  Johnston, B. (Principal Investigator), Florence, A. (Co-investigator) & Wareham, B. J. (Research Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/10/14 → 5/02/20

  Project: Research Studentship - Internally Allocated

• BTG: Impact of childhood obesity on cognition, educational attainment and respiratory health: proof of concept of the links, and of the value of the Strathclyde collaboration

  Reilly, J. (Academic), Young, D. (Academic), Revie, M. (Academic), Boyter, A. (Academic) & Johnston, B. (Academic)

  14/04/14 → 14/07/14

  Project: Internally funded project

  • Childhood Obesity 100%
  • Asthma 100%
  • Interdisciplinary Collaboration 100%
  • Cohort Analysis 100%
  • Mental Capacity 100%

• Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Gurung, Rajesh

  Florence, A. (Principal Investigator), Johnston, B. (Co-investigator) & Gurung, R. (Research Co-investigator)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/10/13 → 3/02/20

  Project: Research Studentship - Internally Allocated

• Intelligent Decision Support Technologies for Continuous Manufacture

  Andonovic, I. (Principal Investigator), Bititci, U. (Co-investigator), Florence, A. (Co-investigator), Gachagan, A. (Co-investigator), Johnston, B. (Co-investigator), Marshall, S. (Co-investigator), Michie, C. (Co-investigator), Mulholland, A. (Co-investigator), Nordon, A. (Co-investigator), Sefcik, J. (Co-investigator) & Vasile, M. (Co-investigator)

  Novartis Pharma AG, Bayer Healthcare AG, EPSRC (Engineering and Physical Sciences Research Council), AstraZeneca UK Limited, Glaxo Smithkline (UK)

  1/02/13 → 31/07/18

  Project: Research

  • User 100%
  • Decision Support System 97%
  • Application 97%
  • Particle Size 78%
  • Shape 62%

• SMSdrug.net: Alignment Of Synthesis, Medicinal Chemistry And Strucrural Genomics To Accelerate Uk Drug Discovery: Network SMS-Drug

  Tomkinson, N. (Principal Investigator), C. Bagley, M. (Academic), Feilden, H. (Academic), Johnston, B. (Academic), Knapp, S. (Academic), MacKay, S. (Academic), Overington, J. (Academic) & Spencer, J. (Academic)

  EPSRC (Engineering and Physical Sciences Research Council)

  1/09/11 → 31/08/15

  Project: Research

  • DNA 100%
  • Ispinesib 50%
  • Synthesis 50%
  • Kinesin 50%
  • Probe 50%

• Thiolactomycin and related inhibitors targeting fatty acid elongase enzymes in Mycobacterium tuberculosis

  MacKay, S. (Principal Investigator), Coxon, G. (Co-investigator) & Johnston, B. (Co-investigator)

  Wellcome Trust

  1/05/05 → 30/04/08

  Project: Research