1993 …2022

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 26 Article
  • 1 Meeting abstract
  • 1 Conference Contribution
Filter
Article
2019
2018

CaMKIIδ interacts directly with IKKβ and modulates NF-kB signalling in adult cardiac fibroblasts

Martin, T. P., McCluskey, C., Cunningham, M. R., Beattie, J., Paul, A. & Currie, S., 27 Jul 2018, In : Cellular Signalling.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
11 Downloads (Pure)

Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells

Ng, P. Y., McIntosh, K. A., Hargrave, G., Ho, K. H., Paul, A. & Plevin, R., 30 Nov 2018, In : Cellular Signalling. 51, p. 59-71 13 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
10 Downloads (Pure)
2017

Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers

Anthony, N. G., Baiget, J., Berretta, G., Boyd, M., Breen, D., Edwards, J., Gamble, C., Gray, A. I., Harvey, A. L., Hatziieremia, S., Ho, K. H., Huggan, J. K., Lang, S., Llona-Minguez, S., Luo, J. L., McIntosh, K., Paul, A., Plevin, R. J., Robertson, M. N., Scott, R. & 4 others, Suckling, C. J., Sutcliffe, O. B., Young, L. C. & MacKay, S. P., 24 Jul 2017, In : Journal of Medicinal Chemistry. 60, 16, p. 7043-7066 24 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
130 Downloads (Pure)

The relationship between members of the canonical NF-κB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer

Bennett, L., Mallon, E. A., Horgan, P. G., Paul, A., McMillan, D. C. & Edwards, J., 9 Mar 2017, In : Oncotarget. 8, 20, p. 33002-33013 12 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
12 Downloads (Pure)
2016

High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer

Bennett, L., Quinn, J., McCall, P., Mallon, E. A., Horgan, P. G., McMillan, D. C., Paul, A. & Edwards, J., 22 Dec 2016, In : International Journal of Cancer. 12 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
10 Downloads (Pure)
2014

Adult cardiac fibroblast proliferation is modulated by calcium/calmodulin-dependent protein kinase II in normal and hypertrophied hearts

Martin, T. P., Lawan, A., Robinson, E., Grieve, D. J., Plevin, R., Paul, A. & Currie, S., 28 Feb 2014, In : Pflugers Archiv - European Journal of Physiology. 466, 2, p. 319–330 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2012

Design and synthesis of EGFR dimerization inhibitors and evaluation of their potential in the treatment of psoriasis

Petch, D., Anderson, R. J., Cunningham, A., George, S. E., Hibbs, D. E., Liu, R., Mackay, S. P., Paul, A., Small, D. A. P. & Groundwater, P. W., 1 Oct 2012, In : Bioorganic and Medicinal Chemistry. 20, 19, p. 5901-5914 14 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Nuclear factor κB predicts poor outcome in patients with hormone-naive prostate cancer with high nuclear androgen receptor

MacKenzie, L., McCall, P., Hatziieremia, S., Catlow, J., Adams, C., McArdle, P., Seywright, M., Tanahill, C., Paul, A., Underwood, M., Mackay, S., Plevin, R. & Edwards, J., Sep 2012, In : Human pathology. 43, 9, p. 1491-500 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Surgical optimization and characterization of a minimally invasive aortic banding procedure to induce cardiac hypertrophy in mice

Martin, T. P., Robinson, E., Harvey, A. P., Macdonald, M., Grieve, D. J., Paul, A. & Currie, S., 1 Jul 2012, In : Experimental Physiology. 97, 7, p. 822-832 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2011

Inhibitory kappa B kinases as targets for pharmacological regulation

Gamble, C., McIntosh, K., Scott, R., Ho, K. H., Plevin, R. & Paul, A., 2011, In : British Journal of Pharmacology. 165, 4, p. 802–819 18 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2010

Characterisation of P2X receptors expressed in rat pulmonary arteries

Syed, N-I-H., Tengah, A., Paul, A. & Kennedy, C., 15 Dec 2010, In : European Journal of Pharmacology. 649, 1-3, p. 342-348 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Differential modulation of TLR-3 and TLR-4 mediated dendritic cell maturation and function by progesterone

Jones, L. A., Kreem, S., Shweash, M., Paul, A., Alexander, J. & Roberts, C. W., 15 Oct 2010, In : Journal of Immunology. 185, 8, p. 4525-4534 10 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2007

IKKalpha and IKKbeta function in TNFalpha-stimulated adhesion molecule expression in human aortic smooth muscle cells

MacKenzie, C., Ritchie, E., Paul, A. & Plevin, R. J., 2007, In : Cellular Signalling. 19, p. 75-80 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
20 Citations (Scopus)
2006
87 Citations (Scopus)
2005
13 Citations (Scopus)
2004

Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway

Cameron, P., McGachy, H. A., Anderson, M., Paul, A., Coombs, G. H., Mottram, J. C., Alexander, J. & Plevin, R. J., Sep 2004, In : Journal of Immunology. 173, 5, p. 3297-3304 7 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Switching leukemia cell phenotype between life and death

Tucker, S. J., Rae, C., Littlejohn, A. F., Paul, A. & MacEwan, D. J., 2004, In : Proceedings of the National Academy of Sciences . 101, 35, p. 12940-12945 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2002

Essential role for verotoxin in sustained stress-activated protein kinase and nuclear factor kappa b signaling, stimulated by escherichia coli o157:H7 in vero cells

Cameron, P., Bingham, D., Paul, A., Pavelka, M., Cameron, S., Rotondo, D. & Plevin, R. J., 2002, In : Infection and Immunity. 70, 10, p. 5370-5380 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2001

Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock

McDonald, M. C., Mota-Filipe, H., Paul, A., Cuzzocrea, S., Abdelrahman, M., Harwood, S., Plevin, R. J., Chatterjee, P. K., Yaqoob, M. M. & Thiemermann, C., 2001, In : FASEB Journal. 15, 1, p. 171-186 15 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)
19 Citations (Scopus)

Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa b kinases in NCTC 2544 keratinocytes

Kanke, T., MacFarlane, S. R., Seatter, M. J., Davenport, E. L., Paul, A., McKenzie, R. C. & Plevin, R. J., 2001, In : Journal of Biological Chemistry. 276, 34, p. 31657-31666 10 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)
2000
Open Access
24 Citations (Scopus)
1999

Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages

Paul, A., Cuenda, A., Bryant, C. E., Murray, J., Chilvers, E. R., Cohen, P., Gould, G. W. & Plevin, R., 1 Jul 1999, In : Cellular Signalling. 11, 7, p. 491-497 7 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)
1993

Phosphatidylcholine hydrolysis: a multiple messenger generating system

Wakelam, M. J., Pettitt, T. R., Kaur, P., Briscoe, C. P., Stewart, A., Paul, A., Paterson, A., Cross, M. J., Gardner, S. D. & Currie, S., 1993, In : Advances in Second Messenger and Phosphoprotein Research. 28, p. 73-80 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)