Projects per year
Personal profile
Personal Statement
Andy holds a Senior Lectureship position in the Strathclyde Institute of Pharmacy and Biomedical Sciences at the University of Strathclyde and has 20 years experience of research and teaching across the Biomedical Science (BMS) and Pharmacy (MPharm) programmes related to application of protein biochemistry and molecular pharmacology, in the context of cellular signalling, to health and disease. Andy is a graduate of the University of Glasgow (BSc (Hons) Biochemistry; 1986-1990) and completed his second degree (PhD Biochemistry & Molecular Biology, 1990-1993) at the University of Glasgow in association with the Wellcome Foundation, Beckenham.
The work in Andy's research lab focusses on the role of the inhibitory kappaB kinases (IKKs) in the regulation of both Nuclear Factor kappaB (NFkappaB)-dependent and -independent transcription in mediating inflammatory-based responses relevant to infection, regulation of immunity, cardiovascular disease and cancer.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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MRC-DPFS Full Application 2023 - Targeting Inhibitory kappa B kinase alpha (IKKalpha): a new treatment paradigm for inflammatory-driven cancers
MacKay, S. (Principal Investigator) & Paul, A. (Co-investigator)
MRC (Medical Research Council)
1/04/24 → 31/03/27
Project: Research
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Development of a first-in-class IKKalpha inhibitor for the treatment of castrate resistant p
MacKay, S. (Principal Investigator), Halbert, G. (Co-investigator), Paul, A. (Co-investigator), Suckling, C. (Co-investigator) & Watson, D. (Co-investigator)
1/10/20 → 31/12/24
Project: Research
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IL-1β stimulates a novel axis within the NFκB pathway in endothelial cells regulated by IKKα and TAK-1
Craig, R., McIntosh, K., Ho, K. H., McCulloch, A., Riley, C., Lawson, C., MacKay, S. P., Paul, A., Coats, P. & Plevin, R., 28 Feb 2025, In: Biochemical Pharmacology. 232, 15 p., 116736.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Design and synthesis of novel aminoindazole-pyrrolo[2,3-b]pyridine inhibitors of IKKα that selectively perturb cellular non-canonical NF-κB signalling
Riley, C., Ammar, U., Alsfouk, A., Anthony, N. G., Baiget, J., Berretta, G., Breen, D., Huggan, J., Lawson, C., McIntosh, K., Plevin, R., Suckling, C. J., Young, L. C., Paul, A. & Mackay, S. P., 26 Jul 2024, In: Molecules. 29, 15, 29 p., 3515.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)34 Downloads (Pure)
Activities
- 1 Key-note speaker and plenary lectures at conferences
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EMBO/FEBS Conference , Spain
Paul, A. (Keynote/plenary speaker)
Jan 2008Activity: Participating in or organising an event types › Key-note speaker and plenary lectures at conferences