Projects per year
Alastair Wark started his career with a BSc in Applied Chemistry in 1996 at the University of Strathclyde. He completed his PhD research in 2000 under the joint supervision of Dr Len Berlouis and Dr Frank Cruikshank at Strathclyde and also working with Prof. Pierre-Francois Brevet at the EPFL, Lausanne, Switzerland. Following post-doctoral research at EPFL he was awarded a Lindemann Trust Fellowship in 2001and joined the laboratories of Prof. Rob Corn at the University of Wisconsin-Madison. After moving across to the University of California-Irvine with Rob’s group and a Project Scientist position, Alastair returned to the Chemistry Department in late 2007 as a Lecturer in Nanometrology.
My research focus is based around the synthesis, functionalization and analytical applications of novel nanomaterials alongside the development of techniques capable of optically imaging and tracking single nanoparticles and molecules. The advantages of these materials for nanometrology and bioanalytical science is that optical measurements can be performed to monitor biomolecular interactions in real-time. As well as developing robust methodologies for ultrasensitive bioaffinity detection at target concentrations approaching just a few molecules, we are also exploring the use of multimodal imaging techniques for monitoring nanoparticle-cellular interactions. This involves developing hybrid nanostructures which can be used for tackling research challenges requiring dynamic measurements in complex biological environments. Consequently, my research is highly multidisciplinary and I have enjoyed successfully collaborating with researchers from across the biology, physics, engineering and medicine research fields.
Expertise & Capabilities
Optical Imaging and Spectroscopy
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Doctor of Philosophy, University of Strathclyde
Award Date: 1 Jan 2000
Bachelor of Science, University of Strathclyde
Award Date: 1 Jan 1996
- Analytical Chemistry
- biomolecular science
- Instrumentation and devices
- surface plasmon resonance
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1/10/21 → 1/04/25
Project: Research Studentship - Internally Allocated
Stimulated Raman scattering microscopy with spectral phasor analysis: applications in assessing drug-cell interactionsTipping, W. J., Wilson, L. T., An, C., Leventi, A. A., Wark, A. W., Wetherill, C., Tomkinson, N. C. O., Faulds, K. & Graham, D., 28 Mar 2022, In: Chemical Science. 13, 12, p. 3468-3476 9 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile7 Downloads (Pure)
A universal polymer shell-isolated nanoparticle (SHIN) design for single particle spectro-electrochemical SERS sensing using different core shapesBoccorh, D. K., MacDonald, P. A., Boyle, C. W., Wain, A. J., Berlouis, L. E. A. & Wark, A. W., 21 Nov 2021, In: Nanoscale Advances. 3, 22, p. 6415-6426 12 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile3 Downloads (Pure)
Data for: "Stimulated Raman scattering microscopy with spectral phasor analysis: applications in assessing drug-cell interactions"
Tipping, W. (Creator), Wilson, L. T. (Contributor), An, C. (Contributor), Leventi, A. A. (Contributor), Wetherill, C. (Contributor), Wark, A. (Contributor), Tomkinson, N. (Contributor), Faulds, K. (Contributor) & Graham, D. (Contributor), University of Strathclyde, 21 Feb 2022
Data for: "A universal polymer shell-isolated nanoparticle (SHIN) design for single particle spectro-electrochemical SERS sensing using different core shapes"
Alastair Wark (Organiser)13 May 2022
Activity: Participating in or organising an event types › Participation in workshop, seminar, course
Alastair Wark (Speaker)13 Jan 2022
Activity: Talk or presentation types › Invited talk