Projects per year
Alastair Wark started his career with a BSc in Applied Chemistry in 1996 at the University of Strathclyde. He completed his PhD research in 2000 under the joint supervision of Dr Len Berlouis and Dr Frank Cruikshank at Strathclyde and also working with Prof. Pierre-Francois Brevet at the EPFL, Lausanne, Switzerland. Following post-doctoral research at EPFL he was awarded a Lindemann Trust Fellowship in 2001and joined the laboratories of Prof. Rob Corn at the University of Wisconsin-Madison. After moving across to the University of California-Irvine with Rob’s group and a Project Scientist position, Alastair returned to the Chemistry Department in late 2007 as a Lecturer in Nanometrology.
My research focus is based around the synthesis, functionalization and analytical applications of novel nanomaterials alongside the development of techniques capable of optically imaging and tracking single nanoparticles and molecules. The advantages of these materials for nanometrology and bioanalytical science is that optical measurements can be performed to monitor biomolecular interactions in real-time. As well as developing robust methodologies for ultrasensitive bioaffinity detection at target concentrations approaching just a few molecules, we are also exploring the use of multimodal imaging techniques for monitoring nanoparticle-cellular interactions. This involves developing hybrid nanostructures which can be used for tackling research challenges requiring dynamic measurements in complex biological environments. Consequently, my research is highly multidisciplinary and I have enjoyed successfully collaborating with researchers from across the biology, physics, engineering and medicine research fields.
Expertise & Capabilities
Optical Imaging and Spectroscopy
Doctor of Philosophy, University of Strathclyde
Award Date: 1 Jan 2000
Bachelor of Science, University of Strathclyde
Award Date: 1 Jan 1996
- Analytical Chemistry
- biomolecular science
- Instrumentation and devices
- surface plasmon resonance
1/10/17 → 30/09/21
Project: Research - Studentship
Gachagan, A., He, W., Jaroszynski, D., Martin, R., McArthur, S., McArthur, S., Connolly, P., Edwards, P., Faulds, K., Florence, A., Graham, D., Leithead, B., Sefcik, J., Ter Horst, J., Trager-Cowan, C., Uttamchandani, D. & Wark, A.
1/08/13 → 28/02/23
Covalent co-assembly between resilin-like polypeptide and peptide amphiphile into hydrogels with controlled nanostructure and improved mechanical propertiesOkesola, B. O., Lau, H. K., Derkus, B., Boccorh, D. K., Wu, Y., Wark, A. W., Kiick, K. L. & Mata, A., 7 Feb 2020, In: Biomaterials Science. 8, 3, p. 846-857 12 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile6 Citations (Scopus)2 Downloads (Pure)
Panagopoulou, M. S., Wark, A. W., Birch, D. J. S. & Gregory, C. D., 31 Jan 2020, In: Journal of Extracellular Vesicles. 9, 1, 18 p., 1710020.
Research output: Contribution to journal › Review article › peer-reviewOpen AccessFile4 Citations (Scopus)3 Downloads (Pure)
Data for "Optimized polydopamine coating and DNA conjugation onto gold nanorods for single nanoparticle bioaffinity measurements"
Alastair Wark (Speaker)18 Jan 2012
Activity: Participating in or organising an event types › Participation in workshop, seminar, course