Projects per year
Personal profile
Personal Statement
Alastair Wark started his career with a BSc in Applied Chemistry in 1996 at the University of Strathclyde. He completed his PhD research in 2000 under the joint supervision of Dr Len Berlouis and Dr Frank Cruikshank at Strathclyde and also working with Prof. Pierre-Francois Brevet at the EPFL, Lausanne, Switzerland. Following post-doctoral research at EPFL he was awarded a Lindemann Trust Fellowship in 2001and joined the laboratories of Prof. Rob Corn at the University of Wisconsin-Madison. After moving across to the University of California-Irvine with Rob’s group and a Project Scientist position, Alastair returned to the Chemistry Department in late 2007 as a Lecturer in Nanometrology.
Research Interests
My research focus is based around the synthesis, functionalization and analytical applications of novel nanomaterials alongside the development of techniques capable of optically imaging and tracking single nanoparticles and molecules. The advantages of these materials for nanometrology and bioanalytical science is that optical measurements can be performed to monitor biomolecular interactions in real-time. As well as developing robust methodologies for ultrasensitive bioaffinity detection at target concentrations approaching just a few molecules, we are also exploring the use of multimodal imaging techniques for monitoring nanoparticle-cellular interactions. This involves developing hybrid nanostructures which can be used for tackling research challenges requiring dynamic measurements in complex biological environments. Consequently, my research is highly multidisciplinary and I have enjoyed successfully collaborating with researchers from across the biology, physics, engineering and medicine research fields.
Expertise & Capabilities
Nanotechnology
Optical Imaging and Spectroscopy
Bioanalytical Chemistry
Surface Chemistry
Education/Academic qualification
Doctor of Philosophy, University of Strathclyde
Bachelor of Science, University of Strathclyde
Keywords
- Nanotechnology
- Analytical Chemistry
- Sensors
- biomolecular science
- Spectroscopy
- Nanoparticles
- Instrumentation and devices
- surface plasmon resonance
- imaging
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
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Projects 2010 2023
NPL contribution to PhD studentship Delali Boccorh
National Physical Laboratory NPL
1/10/17 → 30/09/21
Project: Research - Studentship › Research Studentship
Nanoanalysis for Advanced Materials and Healthcare - EPSRC strategic equipment
Martin, R., Edwards, P., Faulds, K., Florence, A., Graham, D., Sefcik, J., Ter Horst, J., Trager-Cowan, C., Uttamchandani, D. & Wark, A.
EPSRC (Engineering and Physical Sciences Research Council)
8/11/15 → 7/11/19
Project: Research
Research Output 1996 2019
Optimized polydopamine coating and DNA conjugation onto gold nanorods for single nanoparticle bioaffinity measurements
Azab, M. M., Cherif, R., Finnie, A. L., El-Alamin, M. M. A., Sultan, M. A. & Wark, A. W., 7 Apr 2018, In : Analyst. 143, 7, p. 1635-1643 9 p.Research output: Contribution to journal › Article
Second harmonic scattering from silver nanocubes
Russier-Antoine, I., Lee, H. J., Wark, A. W., Butet, J., Benichou, E., Jonin, C., Martin, O. J. F. & Brevet, P-F., 12 Jul 2018, In : Journal of Physical Chemistry C. 122, 30, p. 17447-17455 9 p.Research output: Contribution to journal › Article
Datasets
Data for "Optimized polydopamine coating and DNA conjugation onto gold nanorods for single nanoparticle bioaffinity measurements"
Wark, A. (Creator), University of Strathclyde, 22 Feb 2018
DOI: 10.15129/e3c74c27-809f-4225-a781-0d8d561e00ad
Dataset
Thesis
Real-time, high-throughput assessment of nanoparticle interactions with single-cells using microfluidics : applications in vaccine development
Author: Cunha Matos, C., 1 Apr 2016Supervisor: Wark, A. (Supervisor)
Student thesis: Doctoral Thesis
Prizes
Activities 2008 2012
12th West of Scotland Meeting for Teachers of Chemistry
Alastair Wark (Speaker)Activity: Participating in or organising an event types › Participation in workshop, seminar, course
PittCon 2012
Alastair Wark (Participant)Activity: Participating in or organising an event types › Participation in conference