Research Output per year
Research Output 1999 2019
- 1 - 50 out of 121 results
- Publication Year, Title (descending)
Engineering of acetaminophen particle attributes using a wet milling crystallisation platform
Ahmed, B., Brown, C. J., McGlone, T., Bowering, D. L., Sefcik, J. & Florence, A. J., 10 Jan 2019, In : International Journal of Pharmaceutics. 554, p. 201-211 11 p.Research output: Contribution to journal › Article
Crystallisation of oxcarbazepine form III: emergence of crystals with variable twisted habit
Polyzois, H., Guo, R., Warzecha, M., Price, S. & Florence, A., 27 Mar 2018. 1 p.Research output: Contribution to conference › Poster
Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations
Brown, C. J., McGlone, T., Yerdelen, S., Srirambhatla, V., Mabbott, F., Gurung, R., Briuglia, M. L., Ahmed, B., Polyzois, H., Mcginty, J., Perciballi, F., Fysikopoulos, D., Macfhionnghaile, P., Siddique, H., Raval, V., Harrington, T. S., Vassileiou, A. D., Robertson, M., Prasad, E., Johnston, A. & 9 others , 1 Jun 2018, In : Molecular Systems Design and Engineering. 3, 3, p. 518-549 32 p.Research output: Contribution to journal › Article
Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisation
Brown, C. J., McGlone, T., Yerdelen, S., Srirambhatla, V., Mabbott, F., Gurung, R., Briuglia, M. L., Ahmed, B., Polyzois, H., McGinty, J., Perciballi, F., Fysikopoulos, D., Macfhionnghaile, P., Siddique, H., Raval, V., Harrington, T. S., Vassileiou, A., Robertson, M., Prasad, E., Johnston, A. & 9 others , 1 Jun 2018, In : Molecular Systems Design & Engineering. 2018, 3, p. 518-549 32 p.Research output: Contribution to journal › Article
Impact of paracetamol impurities on face properties: investigating the surface of single crystals using TOF-SIMS
Ottoboni, S., Chrubasik, M., Mir Bruce, L., Nguyen, T. T. H., Robertson, M., Johnston, B., Oswald, I. D. H., Florence, A. & Price, C., 2 May 2018, In : Crystal Growth and Design. 18, 5, p. 2750–2758 9 p.Research output: Contribution to journal › Article
Injection moulding- A novel method of solid oral dosage form manufacturing
Wood, S., Halbert, G. & Florence, A., 18 Jan 2018. 1 p.Research output: Contribution to conference › Poster
Inkjet printing of oral dosage forms to solubilize BCS Class II drugs
Turner, A. J., Halbert, G. W. & Florence, A. J., 18 Jan 2018.Research output: Contribution to conference › Poster
Monitoring API crystal breakage in wet milling using inline imaging and chord length distribution measurements
Ahmed, B., Svoboda, V., Agimelen, O., Cardona, J., Dziewierz, J., Brown, C., McGlone, T., Cleary, A., Tachtatzis, C., Michie, C., Florence, A. J., Andonovic, I., Mulholland, A. & Sefcik, J., 24 Apr 2018. 2 p.Research output: Contribution to conference › Abstract
Multi-sensor inline measurements of crystal size and shape distributions during high shear wet milling of crystal slurries
Agimelen, O. S., Svoboda, V., Ahmed, B., Cardona, J., Dziewierz, J., Brown, C. J., McGlone, T., Cleary, A., Tachtatzis, C., Michie, C., Florence, A. J., Andonovic, I., Mulholland, A. J. & Sefcik, J., 31 Dec 2018, In : Advanced Powder Technology. 29, 12, p. 2987-2995 9 p.Research output: Contribution to journal › Article
Quantitative investigation of particle formation of a model pharmaceutical formulation using single droplet evaporation experiments and X-ray tomography
Doerr, F. J. S., Oswald, I. D. H. & Florence, A. J., 12 Oct 2018, In : Advanced Powder Technology. 11 p.Research output: Contribution to journal › Article
Rapid continuous antisolvent crystallization of multi-component systems
Raza, S. A., Schacht, U., Svoboda, V., Edwards, D. P., Florence, A. J., Pulham, C. R., Sefcik, J. & Oswald, I. D. H., 3 Jan 2018, In : Crystal Growth and Design. 18, 1, p. 210-218 9 p.Research output: Contribution to journal › Article
Successful computationally directed templating of metastable pharmaceutical polymorphs
Case, D. H., Srirambhatla, V. K., Guo, R., Watson, R. E., Price, L. S., Polyzois, H., Cockcroft, J. K., Florence, A. J., Tocher, D. A. & Price, S. L., 5 Sep 2018, In : Crystal Growth and Design. 18, 9, p. 5322-5331 10 p.Research output: Contribution to journal › Article
The role of in-line image analysis in the transition to continuous manufacturing in the pharmaceutical industry
Cardona, J., Ferreira, C., Svoboda, V., Ahmed, B., McGinty, J., Agimelen, O. S., Hamilton, A., Cleary, A., Atkinson, R., Michie, C., Marshall, S., Florence, A. J., Chen, Y-C., Sefcik, J., Andonovic, I. & Tachtatzis, C., 11 Sep 2018. 6 p.Research output: Contribution to conference › Paper
A factorial approach to understanding the effect of inner geometry of baffled meso-scale tubes on solids suspension and axial dispersion in continuous, oscillatory liquid-solid plug flows
Ejim, L. N., Yerdelen, S., McGlone, T., Onyemelukwe, I., Johnston, B., Florence, A. J. & Reis, N. M., 15 Jan 2017, In : Chemical Engineering Journal. 308, p. 669–682 14 p.Research output: Contribution to journal › Article
Aqueous solubility of organic salts. Investigating trends in a systematic series of 51 crystalline salt forms of methylephedrine
S. de Moraes, L., Edwards, D., Florence, A. J., Johnston, A., Johnston, B. F., Morrison, C. A. & Kennedy, A. R., 7 Jun 2017, In : Crystal Growth and Design. 17, 6, p. 3277-3286 10 p.Research output: Contribution to journal › Article
Direct observation of templated two-step nucleation mechanism during olanzapine hydrate formation
Warzecha, M., Guo, R., Bhardwaj, R. M., Reutzel-Edens, S. M., Price, S. L., Lamprou, D. A. & Florence, A. J., 23 Oct 2017, In : Crystal Growth and Design. p. 1-41 41 p.Research output: Contribution to journal › Article
Inkjet printing scalable dosage forms capable of increasing the solubility of BCS Class II drugs
Turner, A., Halbert, G. & Florence, A., 15 Nov 2017.Research output: Contribution to conference › Poster
Mesoscopic solute-rich clusters in olanzapine solutions
Warzecha, M., Safari, M. S., Florence, A. J. & Vekilov, P. G., 26 Oct 2017, In : Crystal Growth and Design. 9 p.Research output: Contribution to journal › Article
Solid oral dosage form manufacturing using injection moulding
Wood, S., Halbert, G. & Florence, A., 16 Oct 2017. 1 p.Research output: Contribution to conference › Poster
Solid oral dosage form manufacturing using injection moulding
Wood, S., Halbert, G. & Florence, A., 23 Mar 2017.Research output: Contribution to conference › Poster
Spray drying as a reliable route to produce metastable carbamazepine form IV
Halliwell, R. A., Bhardwaj, R. M., Brown, C., Briggs, N. E. B., Dunn, J., Robertson, J., Nordon, A. & Florence, A. J., 19 Apr 2017, In : Journal of Pharmaceutical Sciences. 106, 7, p. 1874-1880 7 p.Research output: Contribution to journal › Article
The solute-rich mesoscopic precursors of crystal nuclei of olanzapine solid forms
Warzecha, M., Vekilov, P. G. & Florence, A., 27 Jun 2017. 1 p.Research output: Contribution to conference › Poster
Achieving immediate release dosage forms using DoE and injection moulding
Wood, S., Halbert, G. W. & Florence, A., 30 Nov 2016. 1 p.Research output: Contribution to conference › Poster
Crystal structure of the co-crystal butylparaben– isonicotinamide (1/1)
Bhardwaj, R. M., Yang, H. & Florence, A. J., 1 Jan 2016, In : Acta Crystallographica Section E: Structure Reports. E72, 1, p. 53-55 3 p.Research output: Contribution to journal › Article
Effect of oscillatory flow on nucleation kinetics of butyl paraben
Yang, H., Yu, X., Raval, V., Makkawi, Y. & Florence, A., 3 Feb 2016, In : Crystal Growth and Design . 16, 2, p. 875-886 12 p.Research output: Contribution to journal › Article
Initial assessment of hot-melt extrusion for processing API with a wide range of physical properties to form consistent solid dispersion: HPMC-Affinisol paracetamol system
Islam, M. T., Robertson, J. & Florence, A. J., 20 Jul 2016, (Accepted/In press). 1 p.Research output: Contribution to conference › Abstract
Injection moulding: a novel approach to the manufacture of homogenous immediate release solid oral dosage forms
Wood, S., Halbert, G. & Florence, A., 5 Sep 2016.Research output: Contribution to conference › Poster
Inkjet printing oral dosage forms
Turner, A. J., Halbert, G. W. & Florence, A. J., 5 Sep 2016. 1 p.Research output: Contribution to conference › Poster
Investigating processing window of Affinisol™ and Plasdone™ - S630 polymers during hot-melt extrusion (for 3D printing by fused deposition modelling)
Islam, M. T., Robertson, J., Tahir, F. & Florence, A., 7 Sep 2016.Research output: Contribution to conference › Poster
Isomorphous template induced crystallisation: a robust method for the targeted crystallisation of computationally predicted metastable polymorphs
Srirambhatla, V., Guo, R., Price, S. L. & Florence, A. J., 11 Jun 2016, In : Chemical Communications. 52, 46, p. 7384-7386 4 p.Research output: Contribution to journal › Article
The impact of paracetamol impurities on face-specific properties: investigating the surface of single crystals using TOF-SIMS
Ottoboni, S., Chrubasik, M., Mir Bruce, L., Nguyen, T. T. H., Johnston, B., Florence, A. & Price, C. J., 28 Jun 2016.Research output: Contribution to conference › Abstract
A random forest model for predicting the crystallisability of organic molecules
Bhardwaj, R. M., Johnston, A., Johnston, B. F. & Florence, A. J., 21 Jun 2015, In : CrystEngComm. 17, 23, p. 4272-4275 4 p.Research output: Contribution to journal › Article
Atomic force microscopy studies on two-step nucleation and epitaxial growth
Warzecha, M., Bhardwaj, R. M., Reutzel-Edens, S., Lamprou, D. & Florence, A., 21 Jun 2015. 1 p.Research output: Contribution to conference › Poster
Crystal structure of a mixed solvated form of amoxapine acetate
Bhardwaj, R. M., Raval, V., Oswald, I. D. H., Florence, A. J. & Stoeckli-Evans, H. (ed.), 1 Feb 2015, In : Acta Crystallographica Section E: Structure Reports. 71, 2, p. 139-141 3 p.Research output: Contribution to journal › Article
Developing a data acquisition, analysis and reporting system for an academic research centre
Robertson, M., McGlone, T., Johnston, A., Florence, A., Johnston, B., Dziewierz, J., Tachtatzis, C., Cleary, A., Gachagan, A., Andonovic, I. & Sefcik, J., 26 Jun 2015. 6 p.Research output: Contribution to conference › Paper
Establishment of a continuous sonocrystallization process for lactose in an oscillatory baffled crystallizer
Siddique, H., Brown, C. J., Houson, I. & Florence, A. J., 18 Dec 2015, In : Organic Process Research and Development. 19, 12, p. 1871-1881 11 p.Research output: Contribution to journal › Article
Image-based monitoring of encrustation in the crystallisation process
Tachtatzis, C., Sheridan, R., Michie, C., Atkinson, R. C., Cleary, A., Dziewierz, J., Andonovic, I., Briggs, N. E. B., Florence, A. J. & Sefcik, J., 8 Sep 2015, In : Chemical Engineering Science . 133, p. 82-90 9 p.Research output: Contribution to journal › Article
Oscillatory flow reactors (OFRs) for continuous manufacturing and crystallization
McGlone, T., Briggs, N. E. B., Clark, C. A., Brown, C. J., Sefcik, J. & Florence, A. J., 18 Sep 2015, In : Organic Process Research and Development. 19, 9, p. 1186–1202 17 p.Research output: Contribution to journal › Article
Seeded crystallization of β-L-glutamic acid in a continuous oscillatory baffled crystallizer
Briggs, N. E. B., Schacht, U., Raval, V., McGlone, T., Sefcik, J. & Florence, A. J., 18 Dec 2015, In : Organic Process Research and Development. 19, 12, p. 1903−1911 9 p.Research output: Contribution to journal › Article
Drug solid solutions - a method for tuning phase transformations
Delori, A., Maclure, P., Bhardwaj, R. M., Johnston, A., Florence, A. J., Sutcliffe, O. B. & Oswald, I. D. H., 14 Jul 2014, In : CrystEngComm. 16, 26, p. 5827-5831 5 p.Research output: Contribution to journal › Article
Formulation of liquid propofol as a cocrystalline solid
McKellar, S. C., Kennedy, A. R., McCloy, N. C., McBride, E. & Florence, A. J., 27 Feb 2014, In : Crystal Growth and Design. 14, 5, p. 2422-2430 9 p.Research output: Contribution to journal › Article
From discovery to scale-up: alpha-lipoic acid: nicotinamide co-crystals in a continuous oscillatory baffled crystalliser
Zhao, L., Raval, V., Briggs, N. E. B., Bhardwaj, R. M., McGlone, T., Oswald, I. D. H. & Florence, A. J., 14 Jul 2014, In : CrystEngComm. 16, 26, p. 5769-5780 12 p.Research output: Contribution to journal › Article
4th European conference for crystal growth-crystallisation in focus: from fundamentals to application
Florence, A. J., 28 Mar 2013, In : CrystEngComm. 15, 12, p. 2174-2174 1 p.Research output: Contribution to journal › Article
Absorbing a little water: the structural, thermodynamic, and kinetic relationship between pyrogallol and its tetarto-hydrate
Braun, D. E., Bhardwaj, R. M., Arlin, J-B., Florence, A. J., Kahlenberg, V., Griesser, U. J., Tocher, D. A. & Price, S. L., 4 Sep 2013, In : Crystal Growth and Design. 13, 9, p. 4071-4083 13 p.Research output: Contribution to journal › Article
A complementary experimental and computational study of loxapine succinate and its monohydrate
Bhardwaj, R. M., Johnston, B. F., Oswald, I. D. H. & Florence, A. J., 1 Nov 2013, In : Acta Crystallographica Section C: Crystal Structure Communications. 69, 11, p. 1273-1378 6 p.Research output: Contribution to journal › Article
Chemical transformations of a crystalline coordination polymer: a multi-stage solid–vapour reaction manifold
Vitorica-Yrezabal, I., Mínguez Espallargas, G., Soleimannejad, J., Florence, A., Fletcher, A. & Brammer, L., 1 Feb 2013, In : Chemical Science. 4, 2, p. 696-708 13 p.Research output: Contribution to journal › Article
Complex polymorphic system of gallic acid-five monohydrates, three anhydrates, and over 20 solvates
Braun, D. E., Bhardwaj, R. M., Florence, A. J., Tocher, D. A. & Price, S. L., 2 Jan 2013, In : Crystal Growth and Design. 13, 1, p. 19-23 5 p.Research output: Contribution to journal › Article
Exploring the experimental and computed crystal energy landscape of olanzapine
Bhardwaj, R. M., Price, L. S., Price, S. L., Reutzel-Edens, S. M., Miller, G. J., Oswald, I. D. H., Johnston, B. F. & Florence, A. J., Apr 2013, In : Crystal Growth and Design. 13, 4, p. 1602-1617 16 p.Research output: Contribution to journal › Article
Zipping and unzipping of a paddlewheel metal-organic framework to enable two-step synthetic and structural transformation
Smart, P., Mason, C. A., Loader, J. R., Meijer, A. J. H. M., Florence, A., Shankland, K., Fletcher, A., Thompson, S. P., Brunelli, M., Hill, A. H. & Brammer, L., 11 Mar 2013, In : Chemistry - A European Journal . 19, 11, p. 3552-3557 6 p.Research output: Contribution to journal › Article
6-Methyl-1,3,5-triazine-2,4-diamine butane-1,4-diol monosolvate
Florence, A., Oswald, I. & Miglani Bhardwaj, R., Dec 2012, In : Acta Crystallographica Section E: Structure Reports. E68, 12, p. o3377 1 p.Research output: Contribution to journal › Article