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Personal profile

Personal Statement

Director of the EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC) and associated 45 PhD Doctoral Training Centre. Leads the new world-class CMAC National Facility within the Technology and Innovation Centre (TIC) at the University of Strathclyde offering access to academic and industrial users to state-of-the art processing, analysis and characterisations facilties and support. Expertise in crystallisation and physical form control and characterisation of pharmaceuticals spanning polymorphism, solvate, co-crystal and salt formation and studies of amorphous systems. Extensive experience in the formation of pharmaceutical particles in continuous processes using a range of technologies as part of the CMAC programme. Interests also in the development and application of new technologies to control and monitor crystallisation and pharmaceutical solids.

Approaches for the characterisation of particles are also widely used and physical analysis of crystalline pharmaceuticals with a focus on the influence of crystallisation processes on structure and critical pharmaceutically relevant attributes that dictates product performance. Exploitation of X-ray powder diffraction techniques for phase identification, structure determination from powder diffraction data and in-situ phase surveys including local order using variable-temperature X-ray powder diffraction are key areas.

Has published over 120 peer reviewed research papers in these areas and currently supervises a large multidisciplinary research group including pharmacists, chemists and chemical engineers.

External positions

Advisory board member , Functional Materials Manufacturing Programme, Imperial College

2015 → …

Advisory board member, Leeds University

2015 → …

Chairman, British Association of Crystal Growth

2014 → …

Innovation Strategy Board member, KTN

2014 → …

Fingerprint Dive into the research topics where Alastair Florence is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Dimers Engineering & Materials Science

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2003 2023

Research Output 1987 2019

Developing process understanding for continuous manufacturing of Lamivudine (Epivir®) Stable Form I

Ojo, E., Hosni, Z., Onyemelukwe, I., Ramakers, L., Houson, I. & Florence, A., 9 Jul 2019. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
Lamivudine
Virus Diseases
Crystallization
Hepatitis B
Research
2 Citations (Scopus)
Extrusion
Printing
Fabrication
Chemical analysis
Pharmaceutical Preparations

Thesis

Batch to continuous organic salt crystallisation : model based design

Author: McGinty, J., 1 Jul 2017

Supervisor: Sefcik, J. (Supervisor) & Florence, A. (Supervisor)

Student thesis: Doctoral Thesis

Continuous crystallisation and form control in a meso-scale oscillatory baffled reactor

Author: Yerdelen, S., 1 Jan 2018

Supervisor: Florence, A. (Supervisor) & Oswald, I. (Supervisor)

Student thesis: Doctoral Thesis

Prizes

Best Poster Award @ CMAC Annual Open Day 2018

Zied Hosni (Recipient), Ebenezer Ojo (Recipient), Ikechukwu Onyemelukwe (Recipient), Lennart Ramakers (Recipient), Ian Houson (Recipient) & Alastair Florence (Recipient), 25 Oct 2018

Prize: Prize (including medals and awards)

Royal Pharmaceutical Society of Great Britain Conference Science Medal

Alastair Florence (Recipient), Sep 2004

Prize: Prize (including medals and awards)

Medal

Activities 2008 2019

EPSRC Hub Directors Meeting (Event)

Alastair Florence (Member)
11 Jun 2019

Activity: Membership typesMembership of committee

Centre for International Manufacturing, Institute for Manufacturing, University of Cambridge

Alastair Florence (Visiting researcher)
21 Jun 2019

Activity: Visiting an external institution typesVisiting an external academic institution