Projects per year
Director of the EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC) and associated 45 PhD Doctoral Training Centre. Leads the new world-class CMAC National Facility within the Technology and Innovation Centre (TIC) at the University of Strathclyde offering access to academic and industrial users to state-of-the art processing, analysis and characterisations facilties and support. Expertise in crystallisation and physical form control and characterisation of pharmaceuticals spanning polymorphism, solvate, co-crystal and salt formation and studies of amorphous systems. Extensive experience in the formation of pharmaceutical particles in continuous processes using a range of technologies as part of the CMAC programme. Interests also in the development and application of new technologies to control and monitor crystallisation and pharmaceutical solids.
Approaches for the characterisation of particles are also widely used and physical analysis of crystalline pharmaceuticals with a focus on the influence of crystallisation processes on structure and critical pharmaceutically relevant attributes that dictates product performance. Exploitation of X-ray powder diffraction techniques for phase identification, structure determination from powder diffraction data and in-situ phase surveys including local order using variable-temperature X-ray powder diffraction are key areas.
Has published over 120 peer reviewed research papers in these areas and currently supervises a large multidisciplinary research group including pharmacists, chemists and chemical engineers.
Advisory board member , Functional Materials Manufacturing Programme, Imperial College2015 → …
Advisory board member, Leeds University2015 → …
Chairman, British Association of Crystal Growth2014 → …
Innovation Strategy Board member, KTN2014 → …
1/10/18 → 1/10/21
Project: Research Studentship - Internally Allocated › Research Studentship (Internally Allocated)
Research Output per year
Research output: Contribution to conference › Poster
Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisationBrown, C. J. , McGlone, T. , Yerdelen, S. , Srirambhatla, V. , Mabbott, F. , Gurung, R. , Briuglia, M. L. , Ahmed, B. , Polyzois, H. , McGinty, J. , Perciballi, F. , Fysikopoulos, D. , Macfhionnghaile, P. , Siddique, H. , Raval, V. , Harrington, T. S. , Vassileiou, A. , Robertson, M. , Prasad, E. , Johnston, A. & 9 others , 1 Jun 2018, In : Molecular Systems Design & Engineering. 2018, 3, p. 518-549 32 p.
Research output: Contribution to journal › Article
Data for: "Fusion of laser diffraction and chord length distribution data for estimation of particle size distribution using multi-objective optimisation"
Agimelen, O. S. (Creator), University of Strathclyde, 13 Sep 2018
Data for: "Quantitative Investigation of Particle Formation of a Model Pharmaceutical Formulation using Single Droplet Evaporation Experiments and X-Ray Tomography"
Doerr, F. (Creator), University of Strathclyde, 18 Oct 2018
Student thesis: Doctoral Thesis
Student thesis: Doctoral Thesis
Activities per year