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Personal profile

Personal Statement

Director of the EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC) and associated 45 PhD Doctoral Training Centre. Leads the new world-class CMAC National Facility within the Technology and Innovation Centre (TIC) at the University of Strathclyde offering access to academic and industrial users to state-of-the art processing, analysis and characterisations facilties and support. Expertise in crystallisation and physical form control and characterisation of pharmaceuticals spanning polymorphism, solvate, co-crystal and salt formation and studies of amorphous systems. Extensive experience in the formation of pharmaceutical particles in continuous processes using a range of technologies as part of the CMAC programme. Interests also in the development and application of new technologies to control and monitor crystallisation and pharmaceutical solids.

Approaches for the characterisation of particles are also widely used and physical analysis of crystalline pharmaceuticals with a focus on the influence of crystallisation processes on structure and critical pharmaceutically relevant attributes that dictates product performance. Exploitation of X-ray powder diffraction techniques for phase identification, structure determination from powder diffraction data and in-situ phase surveys including local order using variable-temperature X-ray powder diffraction are key areas.

Has published over 120 peer reviewed research papers in these areas and currently supervises a large multidisciplinary research group including pharmacists, chemists and chemical engineers.

External positions

Advisory board member , Functional Materials Manufacturing Programme, Imperial College

2015 → …

Advisory board member, Leeds University

2015 → …

Chairman, British Association of Crystal Growth

2014 → …

Innovation Strategy Board member, KTN

2014 → …

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2003 2023

DTP 2018-19 University of Strathclyde | Johnston, Jenna

Florence, A., Halbert, G. & Johnston, J.

EPSRC (Engineering and Physical Sciences Research Council)

1/10/181/10/21

Project: Research Studentship - Internally AllocatedResearch Studentship (Internally Allocated)

Research Output 1999 2019

Crystallisation of oxcarbazepine form III: emergence of crystals with variable twisted habit

Polyzois, H., Guo, R., Warzecha, M., Price, S. & Florence, A., 27 Mar 2018 1 p.

Research output: Contribution to conferencePoster

Open Access
File
Crystallization
Habits
X-Ray Diffraction
Anticonvulsants
Powders
Open Access
File
Workflow
Crystallization
Cooling
Pharmaceutical Preparations
Process design

Thesis

Batch to continuous organic salt crystallisation : model based design

Author: McGinty, J., 1 Jul 2017

Supervisor: Sefcik, J. (Supervisor) & Florence, A. (Supervisor)

Student thesis: Doctoral Thesis

Control of crystalline particle properties by spray drying

Author: Halliwell, R., 1 Mar 2017

Supervisor: Florence, A. (Supervisor) & Sefcik, J. (Supervisor)

Student thesis: Doctoral Thesis

Prizes

Royal Pharmaceutical Society of Great Britain Conference Science Medal

Alastair Florence (Recipient), Sep 2004

Prize: Prize (including medals and awards)

Medal

Activities 2008 2016

Advanced Process Modelling Forum

Florence, A. (Invited speaker)
20 Apr 2016

Activity: Participating in or organising an eventParticipation in conference

QbD symposium

Florence, A. (Invited speaker)
16 Mar 2016

Activity: Participating in or organising an eventParticipation in conference