Strathclyde Institute Of Pharmacy And Biomedical Sciences

  • United Kingdom

Research Output

Filter
Literature review
2019
2018

Sphingosine 1-phosphate and cancer

Pyne, N. J., El Buri, A., Adams, D. R. & Pyne, S., 12 May 2018, In : Advances in Biological Regulation. 68, p. 97-106 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
21 Citations (Scopus)
88 Downloads (Pure)
2017

Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells

Laté de Laté, P., Pineda, M., Harnett, M., Harnett, W., Besteiro, S. & Langsley, G., 28 Feb 2017, In : Biomedical Journal. 40, 1, p. 23-30 8 p.

Research output: Contribution to journalLiterature review

Open Access
File
2 Citations (Scopus)
93 Downloads (Pure)

Can parasitic worms cure the modern world's ills?

Harnett, M. M. & Harnett, W., 9 Jun 2017, In : Trends in Parasitology. 12 p.

Research output: Contribution to journalLiterature review

Open Access
File
11 Citations (Scopus)
22 Downloads (Pure)

P2Y11 receptors: properties, distribution and functions

Kennedy, C., 26 Jul 2017, (Accepted/In press) In : Advances in Experimental Medicine and Biology.

Research output: Contribution to journalLiterature review

Open Access
File
76 Downloads (Pure)

Sphingosine kinase 2 in autoimmune/inflammatory disease and development of sphingosine kinase 2 inhibitors

Pyne, N. J., Adams, D. R. & Pyne, S., 31 Jul 2017, In : Trends in Pharmacological Sciences. 38, 7, p. 581-591 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
10 Citations (Scopus)
17 Downloads (Pure)
2016

Sphingosine 1-phosphate and sphingosine kinases in health and disease: recent advances

Pyne, S., Adams, D. R. & Pyne, N. J., 1 Apr 2016, In : Progress in Lipid Research. 62, p. 93-106 14 p.

Research output: Contribution to journalLiterature review

Open Access
File
70 Citations (Scopus)
130 Downloads (Pure)

Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies

Evangelisti, C., Evangelisti, C., Buontempo, F., Lonetti, A., Orsini, E., Chiarini, F., Barata, J. T., Pyne, S., Pyne, N. J. & Martelli, A. M., 1 Nov 2016, In : Leukemia. 30, p. 2142–2151 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
14 Citations (Scopus)
205 Downloads (Pure)
2015

ATP as a cotransmitter in the autonomic nervous system

Kennedy, C., Sep 2015, In : Autonomic Neuroscience: Basic and Clinical . 191, p. 2-15 14 p.

Research output: Contribution to journalLiterature review

Open Access
File
21 Citations (Scopus)
108 Downloads (Pure)

Choice and design of adjuvants for parenteral and mucosal vaccines

Savelkoul, H. F. J., Ferro, V. A., Strioga, M. M. & Schjins, V. E. J. C., 5 Mar 2015, In : Vaccines. 3, 1, p. 148-171 24 p.

Research output: Contribution to journalLiterature review

Open Access
File
39 Citations (Scopus)
144 Downloads (Pure)

The physiology of protein S-acylation

Chamberlain, L. H. & Shipston, M. J., 1 Apr 2015, In : Physiological Reviews. 95, 2, p. 341-376 36 p.

Research output: Contribution to journalLiterature review

Open Access
File
98 Citations (Scopus)
158 Downloads (Pure)

The re-emergence of natural products for drug discovery in the genomics era

Harvey, A., Edrada-Ebel, R. & Quinn, R. J., 23 Jan 2015, In : Nature Reviews Drug Discovery . 14, p. 111–129 19 p.

Research output: Contribution to journalLiterature review

Open Access
File
880 Citations (Scopus)
488 Downloads (Pure)
2014

ESCRT function in cytokinesis: location, dynamics and regulation by mitotic kinases

Bhutta, M. S., McInerny, C. J. & Gould, G. W., 25 Nov 2014, In : International Journal of Molecular Sciences. 15, 12, p. 21723-21739 17 p.

Research output: Contribution to journalLiterature review

Open Access
File
15 Citations (Scopus)
71 Downloads (Pure)

New links between S-acylation and cancer

Greaves, J. & Chamberlain, L., May 2014, In : Journal of Pathology. 233, 1, p. 4-6 3 p.

Research output: Contribution to journalLiterature review

19 Citations (Scopus)

Novel treatment strategies for schizophrenia from improved understanding of genetic risk

Morris, B. J. & Pratt, J. A., Nov 2014, In : Clinical Genetics. 86, 5, p. 401-411 11 p.

Research output: Contribution to journalLiterature review

Open Access
File
11 Citations (Scopus)
150 Downloads (Pure)

Prediction of soluble heterologous protein expression levels in Escherichia coli from sequence-based features and its potential in biopharmaceutical process development

Dai, X., Guo, W., Long, Q., Yang, Y., Harvey, L., McNeil, B. & Bai, Z., 2014, In : Pharmaceutical Bioprocessing. 2, 3, p. 253-266 14 p.

Research output: Contribution to journalLiterature review

The role of sphingosine 1-phosphate in inflammation and cancer

Pyne, N. J., Ohotski, J., Bittman, R. & Pyne, S., Jan 2014, In : Advances in Biological Regulation. 54, p. 121-129 9 p.

Research output: Contribution to journalLiterature review

Open Access
File
39 Citations (Scopus)
174 Downloads (Pure)
2013

Evolving views on protein palmitoylation (Comment on DOI 10.1002/bies.201300076)

Chamberlain, L., Nov 2013, In : BioEssays. 35, 11, p. 928 1 p.

Research output: Contribution to journalLiterature review

Postgraduate education in clinical pharmacy in Europe

Kinnear, M., 1 Dec 2013, In : Newsletter - European Society of Clinical Pharmacy. 161, p. 5

Research output: Contribution to journalLiterature review

2012

Advancing schizophrenia drug discovery: optimizing rodent models to bridge the translational gap

Pratt, J., Winchester, C., Dawson, N. & Morris, B., Jul 2012, In : Nature Reviews Drug Discovery . 11, 7, p. 560-579 20 p.

Research output: Contribution to journalLiterature review

95 Citations (Scopus)
18 Downloads (Pure)

Development of clinical pharmacy education in UK

Kinnear, M., May 2012, In : Newsletter - European Society of Clinical Pharmacy. 155, p. 5 1 p.

Research output: Contribution to journalLiterature review

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agnello, M., Al-Zeer, M. A., Chan, E., Coombs, G., Menzies, F. M. & Mottram, J., Apr 2012, In : Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journalLiterature review

2435 Citations (Scopus)
Open Access
25 Citations (Scopus)

Measuring protein dynamics with ultrafast two-dimensional infrared spectroscopy

Adamczyk, K., Candelaresi, M., Robb, K., Gumiero, A., Walsh, M. A., Parker, A. W., Hoskisson, P. A., Tucker, N. P. & Hunt, N. T., Jun 2012, In : Measurement Science and Technology . 23, 6, 16 p., 062001.

Research output: Contribution to journalLiterature review

23 Citations (Scopus)

Regulation and function of uncoordinated-51 like kinase proteins

Chan, E. Y., 1 Sep 2012, In : Antioxidants and Redox Signaling. 17, 5, p. 775-785 11 p.

Research output: Contribution to journalLiterature review

37 Citations (Scopus)

Sphingosine 1 phosphate signalling in cancer

Pyne, N. J., Tonelli, F., Lim, K. G., Long, J. S., Edwards, J. & Pyne, S., 2012, In : Biochemical Society Transactions. 40, 1, p. 94-100 7 p.

Research output: Contribution to journalLiterature review

85 Citations (Scopus)

Strategies and challenges involved in the discovery of new chemical entities during early-stage tuberculosis drug discovery

Coxon, G., Cooper, C. B., Gillespie, S. H. & McHugh, T. D., 22 Mar 2012, In : Journal of Infectious Diseases.

Research output: Contribution to journalLiterature review

16 Citations (Scopus)

Targeting sphingosine kinase 1 in cancer

Pyne, N. J., Tonelli, F., Lim, K. G., Long, J., Edwards, J. & Pyne, S., Jan 2012, In : Advances in Biological Regulation. 52, 1, p. 31–38 8 p.

Research output: Contribution to journalLiterature review

21 Citations (Scopus)

Therapeutic implications of disorders of cell death signalling: membranes, micro-environment, and eicosanoid and docosanoid metabolism

Davidson, J., Rotondo, D., Rizzo, M. & Leaver, A., 6 Jun 2012, In : British Journal of Pharmacology. 166, 4, p. 1193-1210 18 p.

Research output: Contribution to journalLiterature review

27 Citations (Scopus)
2011

Advanced breast cancer incidence following population-based mammographic screening

Autier, P., Boniol, M., Middleton, R., Doré, J. F., Héry, C., Zheng, T. & Gavin, A., Aug 2011, In : Annals of Oncology. 22, 8, p. 1726-1735 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
92 Citations (Scopus)
50 Downloads (Pure)

Cellular trans-differentiation and morphogenesis towards the lymphatic lineage in regenerative medicine

Laco, F., Grant, M. H., Flint, D. J. & Black, R. A., Feb 2011, In : Stem Cells and Development. 20, 2, p. 181-195

Research output: Contribution to journalLiterature review

6 Citations (Scopus)

Currrent status and research strategies in tuberculosis drug development

Dover, L. G. & Coxon, G., 2011, In : Journal of Medicinal Chemistry. 54, 18, p. 6157–6165 9 p.

Research output: Contribution to journalLiterature review

90 Citations (Scopus)

Indirect modulation of neuronal excitability and synaptic transmission in the hippocampus by activation of proteinase-activated receptor-2

Gan, J., Greenwood, S. M., Cobb, S. R. & Bushell, T. J., Jul 2011, In : British Journal of Pharmacology. 163, 5, p. 984-994 11 p.

Research output: Contribution to journalLiterature review

26 Citations (Scopus)

Operating bioreactors for microbial exopolysaccharide production

Seviour, R. J., McNeil, B., Fazenda, M. L. & Harvey, L. M., Jun 2011, In : Critical Reviews in Biotechnology. 31, 2, p. 170-185 16 p.

Research output: Contribution to journalLiterature review

29 Citations (Scopus)

Oxidative stress in fungal fermentation processes: the roles of alternative respiration

Li, Q., Bai, Z., O'Donnell, A., Harvey, L. M., Hoskisson, P. A. & McNeil, B., Mar 2011, In : Biotechnology Letters. 33, 3, p. 457-467 11 p.

Research output: Contribution to journalLiterature review

26 Citations (Scopus)

The potential of cucurbit[n]urils in drug delivery

Walker, S., Oun, R., Mcinnes, F. & Wheate, N., May 2011, In : Israel Journal of Chemistry. 51, 5-6, p. 616-624 9 p.

Research output: Contribution to journalLiterature review

189 Citations (Scopus)

Translational aspects of sphingosine 1-phosphate biology

Pyne, S. & Pyne, N. J., 2011, In : Trends in Molecular Medicine. 17, p. 463-472

Research output: Contribution to journalLiterature review

52 Citations (Scopus)
2010

Current strategies for drug discovery through natural products

Harvey, A., Clark, R., Mackay, S. & Johnston, B., Jun 2010, In : Expert Opinion on Drug Discovery. 5, 6, p. 559-568 10 p.

Research output: Contribution to journalLiterature review

51 Citations (Scopus)

Cyclic AMP signalling in pancreatic islets

Furman, B. L., Ong, W. K. & Pyne, N. J., 2010, In : Advances in Experimental Medicine and Biology. 654, p. 281-304 23 p.

Research output: Contribution to journalLiterature review

Open Access
File
60 Citations (Scopus)
585 Downloads (Pure)

Efficacy of anti-cancer agents in cell lines versus human primary tumour tissue

Cree, I. A., Glaysher, S. & Harvey, A. L., Aug 2010, In : Current Opinion in Pharmacology. 10, 4, p. 375-9 5 p.

Research output: Contribution to journalLiterature review

71 Citations (Scopus)

High-pressure structural studies of energetic materials

Millar, D. I. A., Marshall, W. G., Oswald, I. D. H. & Pulham, C. R., 2010, In : Crystallography Reviews. 16, 2, p. 115-132 18 p.

Research output: Contribution to journalLiterature review

34 Citations (Scopus)

High-throughput screening of natural products for cancer therapy

Harvey, A. L. & Cree, I. A., Aug 2010, In : Planta Medica. 76, 11, p. 1080-1086 7 p.

Research output: Contribution to journalLiterature review

46 Citations (Scopus)

High throughput surface characterization: a review of a new tool for screening prospective biomedical material arrays

Davies, M. C., Alexander, M. R., Hook, A. L., Yang, J., Mei, Y., Taylor, M., Urquhart, A. J., Langer, R. & Anderson, D. G., Dec 2010, In : Journal of Drug Targeting. 18, 10, p. 741-751 11 p.

Research output: Contribution to journalLiterature review

29 Citations (Scopus)

Pharmacotherapy to improve outcomes in infrainguinal bypass graft surgery: a review of current treatment strategies

Jackson, A. J., Coats, P., Orr, D. J., Teenan, R. P. & Wadsworth, R. M., 6 May 2010, In : Annals of Vascular Surgery . 24, 4, p. 562-572 11 p.

Research output: Contribution to journalLiterature review

3 Citations (Scopus)

The drug discovery portal: a resource to enhance drug discovery from academia

Clark, R. L., Johnston, B. F., Mackay, S. P., Breslin, C. J., Robertson, M. N. & Harvey, A. L., Aug 2010, In : Drug Discovery Today. 15, 15-16, p. 679-683 5 p.

Research output: Contribution to journalLiterature review

23 Citations (Scopus)
2009

Evolution of Atg1 function and regulation

Chan, E. Y. & Tooze, S. A., 16 Aug 2009, In : Autophagy. 5, 6, p. 758-765 8 p.

Research output: Contribution to journalLiterature review

90 Citations (Scopus)

mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex

Chan, E. Y., 18 Aug 2009, In : Science Signaling. 2, 84, p. pe51

Research output: Contribution to journalLiterature review

141 Citations (Scopus)

New aspects of sphingosine 1-phosphate signaling in mammalian cells

Pyne, N. J., Long, J. S., Lee, S. C., Loveridge, C., Gillies, L. & Pyne, S., 2009, In : Advances in Enzyme Regulation. 49, 1, p. 214-221 7 p.

Research output: Contribution to journalLiterature review

15 Citations (Scopus)

Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease

Pyne, S., Lee, S. C., Long, J. S. & Pyne, N. J., Jan 2009, In : Cellular Signalling. 21, 1, p. 14-21 7 p.

Research output: Contribution to journalLiterature review

97 Citations (Scopus)

Targeting sphingosine-1-phosphate signalling for cardioprotection

Kennedy, S., Kane, K. A., Pyne, N. J. & Pyne, S., Apr 2009, In : Current Opinion in Pharmacology. 9, 2, p. 194-201 7 p.

Research output: Contribution to journalLiterature review

27 Citations (Scopus)