Faculty Of Science

  • United Kingdom

Research Output 1971 2020

Filter
Literature review
2019
Human Engineering
Ergonomics
Human engineering
Safety
Technology
2018
14 Citations (Scopus)

Sphingosine 1-phosphate and cancer

Pyne, N. J., El Buri, A., Adams, D. R. & Pyne, S., 12 May 2018, In : Advances in Biological Regulation. 68, p. 97-106 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
Lysosphingolipid Receptors
Neoplasms
Fibroblasts
TNF Receptor-Associated Factor 2
Phosphorylation
8 Citations (Scopus)

Trans-metal-trapping: concealed crossover complexes en route to transmetallation?

Uzelac, M. & Mulvey, R. E., 4 Jun 2018, In : Chemistry - A European Journal. 24, 31, p. 7786-7793 8 p.

Research output: Contribution to journalLiterature review

Open Access
File
Metals
Organometallic Compounds
Gallium
Organometallics
Aluminum
2017
2 Citations (Scopus)

Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells

Laté de Laté, P., Pineda, M., Harnett, M., Harnett, W., Besteiro, S. & Langsley, G., 28 Feb 2017, In : Biomedical Journal. 40, 1, p. 23-30 8 p.

Research output: Contribution to journalLiterature review

Open Access
File
Autophagy
Parasites
Theileria
Apicomplexa
Communicable Disease Control
8 Citations (Scopus)

Can parasitic worms cure the modern world's ills?

Harnett, M. M. & Harnett, W., 9 Jun 2017, In : Trends in Parasitology. 12 p.

Research output: Contribution to journalLiterature review

Open Access
File
Therapeutic Human Experimentation
Immunomodulation
Explosions
Helminths
Autistic Disorder
59 Citations (Scopus)

C–H functionalization for hydrogen isotope exchange

Atzrodt, J., Derdau, V., Kerr, W. J. & Reid, M., 12 Oct 2017, In : Angewandte Chemie International Edition. p. 1-27 27 p.

Research output: Contribution to journalLiterature review

Open Access
File
Isotopes
Hydrogen
Natural Science Disciplines
Tritium
Biological Science Disciplines

P2Y11 receptors: properties, distribution and functions

Kennedy, C., 26 Jul 2017, (Accepted/In press) In : Advances in Experimental Medicine and Biology.

Research output: Contribution to journalLiterature review

Open Access
File
Genes
Adenosine Triphosphate
Purine Nucleotides
Genetic Testing
Type C Phospholipases
8 Citations (Scopus)

Sphingosine kinase 2 in autoimmune/inflammatory disease and development of sphingosine kinase 2 inhibitors

Pyne, N. J., Adams, D. R. & Pyne, S., 31 Jul 2017, In : Trends in Pharmacological Sciences. 38, 7, p. 581-591 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
Autoimmune Diseases
Histone Deacetylase 2
Histone Deacetylase 1
Th17 Cells
Retinoids
2016

Free-electron lasers: echoes of photons past

Campbell, L. T. & McNeil, B. W. J., 28 Jul 2016, In : Nature Photonics. 10, p. 501-502 2 p.

Research output: Contribution to journalLiterature review

Open Access
File
Free electron lasers
Harmonic generation
free electron lasers
Particle accelerators
Light sources
26 Citations (Scopus)

Progress in the development of non-​BET bromodomain chemical probes

Theodoulou, N. H., Tomkinson, N. C. O., Prinjha, R. K. & Humphreys, P. G., 4 Mar 2016, In : ChemMedChem. 11, 5, p. 477-487 11 p.

Research output: Contribution to journalLiterature review

Open Access
File
Research
HIV
Medicine
Neoplasms
Proteins
57 Citations (Scopus)

Sphingosine 1-phosphate and sphingosine kinases in health and disease: recent advances

Pyne, S., Adams, D. R. & Pyne, N. J., 1 Apr 2016, In : Progress in Lipid Research. 62, p. 93-106 14 p.

Research output: Contribution to journalLiterature review

Open Access
File
Health
Protein Isoforms
Lipids
Cardiovascular system
Neurology
13 Citations (Scopus)

Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies

Evangelisti, C., Evangelisti, C., Buontempo, F., Lonetti, A., Orsini, E., Chiarini, F., Barata, J. T., Pyne, S., Pyne, N. J. & Martelli, A. M., 1 Nov 2016, In : Leukemia. 30, p. 2142–2151 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
Hematologic Neoplasms
Sphingosine
Sphingolipids
Ceramides
Neoplasms
2015
39 Citations (Scopus)
Bearings (structural)
Transition metals
Ligands
Catalysts
Metals
18 Citations (Scopus)

ATP as a cotransmitter in the autonomic nervous system

Kennedy, C., Sep 2015, In : Autonomic Neuroscience: Basic and Clinical . 191, p. 2-15 14 p.

Research output: Contribution to journalLiterature review

Open Access
File
Autonomic Nervous System
Adenosine Triphosphate
Purinergic P2X1 Receptors
Smooth Muscle
Neurotransmitter Agents
38 Citations (Scopus)

Choice and design of adjuvants for parenteral and mucosal vaccines

Savelkoul, H. F. J., Ferro, V. A., Strioga, M. M. & Schjins, V. E. J. C., 5 Mar 2015, In : Vaccines. 3, 1, p. 148-171 24 p.

Research output: Contribution to journalLiterature review

Open Access
File
Vaccines
Antigen-Presenting Cells
Antigen Presentation
Cytokines
T-Lymphocytes
9 Citations (Scopus)

Photoluminescent nanosensors for intracellular detection

De La Rica, R. & Kerr, C., 2015, In : Analytical Methods.

Research output: Contribution to journalLiterature review

Open Access
File
Nanosensors
Nanoparticles
Nanodiamonds
Dendrimers
Molecular Probes
21 Citations (Scopus)

Solution-based nanosensors for in-field detection with the naked eye

Paterson, S. & De La Rica, R., 2015, In : Analyst.

Research output: Contribution to journalLiterature review

Open Access
File
Nanosensors
Nanostructures
Nanostructured materials
Point-of-Care Systems
Molecules
83 Citations (Scopus)

Solvation thermodynamics of organic molecules by the molecular integral equation theory: approaching chemical accuracy

Ratkova, E. L., Palmer, D. S. & Fedorov, M. V., 2015, In : Chemical Reviews. 115, 13, p. 6312–6356 45 p.

Research output: Contribution to journalLiterature review

Open Access
File
Solvation
Integral equations
Thermodynamics
Physical chemistry
Molecules
84 Citations (Scopus)

The physiology of protein S-acylation

Chamberlain, L. H. & Shipston, M. J., 1 Apr 2015, In : Physiological Reviews. 95, 2, p. 341-376 36 p.

Research output: Contribution to journalLiterature review

Open Access
File
Acylation
Protein S
Protein Array Analysis
Proteins
Lipids
764 Citations (Scopus)

The re-emergence of natural products for drug discovery in the genomics era

Harvey, A., Edrada-Ebel, R. & Quinn, R. J., 23 Jan 2015, In : Nature Reviews Drug Discovery . 14, p. 111–129 19 p.

Research output: Contribution to journalLiterature review

Open Access
File
Drug Discovery
Genomics
Biological Products
Metabolomics
Proteins
2014
15 Citations (Scopus)

ESCRT function in cytokinesis: location, dynamics and regulation by mitotic kinases

Bhutta, M. S., McInerny, C. J. & Gould, G. W., 25 Nov 2014, In : International Journal of Molecular Sciences. 15, 12, p. 21723-21739 17 p.

Research output: Contribution to journalLiterature review

Open Access
File
Endosomal Sorting Complexes Required for Transport
Cytokinesis
classifying
Sorting
Microtubules
18 Citations (Scopus)

New links between S-acylation and cancer

Greaves, J. & Chamberlain, L., May 2014, In : Journal of Pathology. 233, 1, p. 4-6 3 p.

Research output: Contribution to journalLiterature review

Acylation
Enzymes
Lipoylation
Neoplasms
Intracellular Membranes
11 Citations (Scopus)

Novel treatment strategies for schizophrenia from improved understanding of genetic risk

Morris, B. J. & Pratt, J. A., Nov 2014, In : Clinical Genetics. 86, 5, p. 401-411 11 p.

Research output: Contribution to journalLiterature review

Open Access
File
Schizophrenia
MAP Kinase Signaling System
Synapses
Genes
Genome

Prediction of soluble heterologous protein expression levels in Escherichia coli from sequence-based features and its potential in biopharmaceutical process development

Dai, X., Guo, W., Long, Q., Yang, Y., Harvey, L., McNeil, B. & Bai, Z., 2014, In : Pharmaceutical Bioprocessing. 2, 3, p. 253-266 14 p.

Research output: Contribution to journalLiterature review

Escherichia coli
Proteins
Bioinformatics
Computational Biology
Genes
34 Citations (Scopus)

The role of sphingosine 1-phosphate in inflammation and cancer

Pyne, N. J., Ohotski, J., Bittman, R. & Pyne, S., Jan 2014, In : Advances in Biological Regulation. 54, p. 121-129 9 p.

Research output: Contribution to journalLiterature review

Open Access
File
Inflammation
Neoplasms
Lysosphingolipid Receptors
Sphingolipids
Knockout Mice
2013
15 Citations (Scopus)

Energetic charged particles above thunderclouds

Fuellekrug, M., Diver, D., Pincon, J-L., Phelps, A. D. R., Bourdon, A., Helling, C., Blanc, E., Honary, F., Harrison, R. G., Sauvaud, J-A., Renard, J-B., Lester, M., Rycroft, M., Kosch, M., Horne, R. B., Soula, S. & Gaffet, S., Jan 2013, In : Surveys in Geophysics. 34, 1, p. 1-41 41 p.

Research output: Contribution to journalLiterature review

thundercloud
Earth atmosphere
energetic particles
Charged particles
charged particles

Evolving views on protein palmitoylation (Comment on DOI 10.1002/bies.201300076)

Chamberlain, L., Nov 2013, In : BioEssays. 35, 11, p. 928 1 p.

Research output: Contribution to journalLiterature review

Lipoylation
Proteins
37 Citations (Scopus)

Metal-free syn-dioxygenation of alkenes

Rawling, M. & Tomkinson, N., 2013, In : Organic and Biomolecular Chemistry. 11, 9, p. 1434-1440 7 p.

Research output: Contribution to journalLiterature review

Open Access
File
Alkenes
alkenes
Metals
Osmium
osmium

Postgraduate education in clinical pharmacy in Europe

Kinnear, M., 1 Dec 2013, In : Newsletter - European Society of Clinical Pharmacy. 161, p. 5

Research output: Contribution to journalLiterature review

Pharmacy Education
Education
3 Citations (Scopus)

Sinking inside the box

Pritchard, D., May 2013, In : Journal of Fluid Mechanics. 722, p. 1-4 4 p.

Research output: Contribution to journalLiterature review

sinking
Buoyancy
buoyancy
boxes
Fluids
2012
94 Citations (Scopus)

Advancing schizophrenia drug discovery: optimizing rodent models to bridge the translational gap

Pratt, J., Winchester, C., Dawson, N. & Morris, B., Jul 2012, In : Nature Reviews Drug Discovery . 11, 7, p. 560-579 20 p.

Research output: Contribution to journalLiterature review

Drug Discovery
Rodentia
Schizophrenia
Pharmaceutical Preparations
Therapeutics

A fresh Look at crosslinked polymers

Cormack, P., 15 May 2012, In : Chemistry World. p. 62-63

Research output: Contribution to journalLiterature review

Polymers
E 2011
30 Citations (Scopus)

Atomic spectrometry update. Environmental analysis

Butler, O. T., Cairns, W. R. L., Cook, J. M. & Davidson, C. M., 2012, In : Journal of Analytical Atomic Spectrometry. 27, 2, p. 187-221 35 p.

Research output: Contribution to journalLiterature review

Spectrometry
Metal analysis
Water analysis
Trace analysis
Beverages

Development of clinical pharmacy education in UK

Kinnear, M., May 2012, In : Newsletter - European Society of Clinical Pharmacy. 155, p. 5 1 p.

Research output: Contribution to journalLiterature review

Pharmacy Education
Hospital Pharmacy Services
Formularies
325 Citations (Scopus)

Enzyme-responsive nanoparticles for drug release and diagnostics

De La Rica, R., Aili, D. & Stevens, M., Aug 2012, In : Advanced Drug Delivery Reviews. 64, 11, p. 967-978 12 p.

Research output: Contribution to journalLiterature review

Nanoparticles
enzymes
drugs
Nanostructures
nanoparticles
2350 Citations (Scopus)

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agnello, M., Al-Zeer, M. A., Chan, E., Coombs, G., Menzies, F. M. & Mottram, J., Apr 2012, In : Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journalLiterature review

Autophagy
Guidelines
Lysosomes
Eukaryota
Research Personnel
25 Citations (Scopus)
Open Access
Acanthocheilonema
Phosphorylcholine
Immune System
Glycoproteins
Autoimmunity
20 Citations (Scopus)

Measuring protein dynamics with ultrafast two-dimensional infrared spectroscopy

Adamczyk, K., Candelaresi, M., Robb, K., Gumiero, A., Walsh, M. A., Parker, A. W., Hoskisson, P. A., Tucker, N. P. & Hunt, N. T., Jun 2012, In : Measurement Science and Technology . 23, 6, 16 p., 062001.

Research output: Contribution to journalLiterature review

Infrared Spectroscopy
Infrared spectroscopy
infrared spectroscopy
isotopic labeling
proteins
229 Citations (Scopus)

Molecularly-mediated assemblies of plasmonic nanoparticles for Surface-Enhanced Raman Spectroscopy applications

Guerrini, L. & Graham, D., 2012, In : Chemical Society Reviews. 41, 21, p. 7085-7107 23 p.

Research output: Contribution to journalLiterature review

Raman spectroscopy
Nanoparticles
Nanoscience
Suspensions
Nanotechnology

Parametric instability in scalar gravitational fields

Davies, T. B., Wang, C. H. -T., Bingham, R. & Mendonca, J. T., 10 Aug 2012, In : Modern Physics Letters A . 27, 24, 15 p., 1230023.

Research output: Contribution to journalLiterature review

gravitational fields
scalars
neutron stars
tensors
excitation
33 Citations (Scopus)

Regulation and function of uncoordinated-51 like kinase proteins

Chan, E. Y., 1 Sep 2012, In : Antioxidants and Redox Signaling. 17, 5, p. 775-785 11 p.

Research output: Contribution to journalLiterature review

Autophagy
Protein Kinases
Phosphorylation
AMP-Activated Protein Kinases
Homeostasis
78 Citations (Scopus)

Sphingosine 1 phosphate signalling in cancer

Pyne, N. J., Tonelli, F., Lim, K. G., Long, J. S., Edwards, J. & Pyne, S., 2012, In : Biochemical Society Transactions. 40, 1, p. 94-100 7 p.

Research output: Contribution to journalLiterature review

Lysosphingolipid Receptors
Neoplasms
Tumors
Histone Deacetylase 2
Histone Deacetylase 1
16 Citations (Scopus)

Strategies and challenges involved in the discovery of new chemical entities during early-stage tuberculosis drug discovery

Coxon, G., Cooper, C. B., Gillespie, S. H. & McHugh, T. D., 22 Mar 2012, In : Journal of Infectious Diseases.

Research output: Contribution to journalLiterature review

Drug Discovery
Tuberculosis
Pharmaceutical Preparations
Biosynthetic Pathways
Infection
81 Citations (Scopus)

Surface enhanced Raman scattering for multiplexed detection

Dougan, J. A. & Faulds, K., 2012, In : Analyst. 137, 3, p. 545-554 10 p.

Research output: Contribution to journalLiterature review

Raman Spectrum Analysis
Raman scattering
scattering
Biomolecules
Complex Mixtures
21 Citations (Scopus)

Targeting sphingosine kinase 1 in cancer

Pyne, N. J., Tonelli, F., Lim, K. G., Long, J., Edwards, J. & Pyne, S., Jan 2012, In : Advances in Biological Regulation. 52, 1, p. 31–38 8 p.

Research output: Contribution to journalLiterature review

Prostatic Neoplasms
Neoplasms
Breast Neoplasms
Estrogen Receptors
Recurrence
25 Citations (Scopus)

Therapeutic implications of disorders of cell death signalling: membranes, micro-environment, and eicosanoid and docosanoid metabolism

Davidson, J., Rotondo, D., Rizzo, M. & Leaver, A., 6 Jun 2012, In : British Journal of Pharmacology. 166, 4, p. 1193-1210 18 p.

Research output: Contribution to journalLiterature review

Eicosanoids
Unsaturated Fatty Acids
Cell Death
Membranes
Pathologic Processes
2011
90 Citations (Scopus)

Advanced breast cancer incidence following population-based mammographic screening

Autier, P., Boniol, M., Middleton, R., Doré, J. F., Héry, C., Zheng, T. & Gavin, A., Aug 2011, In : Annals of Oncology. 22, 8, p. 1726-1735 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
Breast Neoplasms
Incidence
Population
Mammography
Netherlands
42 Citations (Scopus)

Assemblies of functional peptides and their applications in building blocks for biosensors

De La Rica, R., Pejoux, C. & Matsui, H., 2011, In : Advanced Functional Materials. 21, 6, p. 1018-1026 9 p.

Research output: Contribution to journalLiterature review

Peptide Nanotubes
bioinstrumentation
Biosensors
assemblies
Peptides
6 Citations (Scopus)

Cellular trans-differentiation and morphogenesis towards the lymphatic lineage in regenerative medicine

Laco, F., Grant, M. H., Flint, D. J. & Black, R. A., Feb 2011, In : Stem Cells and Development. 20, 2, p. 181-195

Research output: Contribution to journalLiterature review

Growth Differentiation Factors
Vascular Endothelial Growth Factor C
Regenerative Medicine
Lymphedema
Interleukins
86 Citations (Scopus)

Currrent status and research strategies in tuberculosis drug development

Dover, L. G. & Coxon, G., 2011, In : Journal of Medicinal Chemistry. 54, 18, p. 6157–6165 9 p.

Research output: Contribution to journalLiterature review

Tuberculosis
Drug and Narcotic Control
Drug Discovery
Research
Pharmaceutical Preparations