Faculty Of Science

  • United Kingdom

Research Output 1971 2019

Filter
Literature review
2018
8 Citations

Sphingosine 1-phosphate and cancer

Pyne, N. J., El Buri, A., Adams, D. R. & Pyne, S., 12 May 2018, In : Advances in Biological Regulation. 68, p. 97-106 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
Lysosphingolipid Receptors
Neoplasms
Fibroblasts
TNF Receptor-Associated Factor 2
Phosphorylation
4 Citations

Trans-metal-trapping: concealed crossover complexes en route to transmetallation?

Uzelac, M. & Mulvey, R. E., 4 Jun 2018, In : Chemistry - A European Journal. 24, 31, p. 7786-7793 8 p.

Research output: Contribution to journalLiterature review

Metals
Organometallic Compounds
Gallium
Organometallics
Aluminum
2017
2 Citations

Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells

Laté de Laté, P., Pineda, M., Harnett, M., Harnett, W., Besteiro, S. & Langsley, G., 28 Feb 2017, In : Biomedical Journal. 40, 1, p. 23-30 8 p.

Research output: Contribution to journalLiterature review

Open Access
File
Autophagy
Parasites
Theileria
Apicomplexa
Communicable Disease Control
2 Citations

Can parasitic worms cure the modern world's ills?

Harnett, M. M. & Harnett, W., 9 Jun 2017, In : Trends in Parasitology. 12 p.

Research output: Contribution to journalLiterature review

Open Access
File
Therapeutic Human Experimentation
Immunomodulation
Explosions
Helminths
Autistic Disorder
20 Citations

C–H functionalization for hydrogen isotope exchange

Atzrodt, J., Derdau, V., Kerr, W. J. & Reid, M., 12 Oct 2017, In : Angewandte Chemie International Edition. p. 1-27 27 p.

Research output: Contribution to journalLiterature review

Open Access
File
Isotopes
Hydrogen
Natural Science Disciplines
Tritium
Biological Science Disciplines

P2Y11 receptors: properties, distribution and functions

Kennedy, C., 26 Jul 2017, (Accepted/In press) In : Advances in Experimental Medicine and Biology.

Research output: Contribution to journalLiterature review

Open Access
File
Genes
Adenosine Triphosphate
Purine Nucleotides
Genetic Testing
Type C Phospholipases
5 Citations

Sphingosine kinase 2 in autoimmune/inflammatory disease and development of sphingosine kinase 2 inhibitors

Pyne, N. J., Adams, D. R. & Pyne, S., 31 Jul 2017, In : Trends in Pharmacological Sciences. 38, 7, p. 581-591 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
Sphingosine
Autoimmune Diseases
Phosphotransferases
Histone Deacetylase 1
Histone Deacetylase 2
2016

Free-electron lasers: echoes of photons past

Campbell, L. T. & McNeil, B. W. J., 28 Jul 2016, In : Nature Photonics. 10, p. 501-502 2 p.

Research output: Contribution to journalLiterature review

Open Access
File
Free electron lasers
Harmonic generation
free electron lasers
Particle accelerators
Light sources
21 Citations

Progress in the development of non-​BET bromodomain chemical probes

Theodoulou, N. H., Tomkinson, N. C. O., Prinjha, R. K. & Humphreys, P. G., 4 Mar 2016, In : ChemMedChem. 11, 5, p. 477-487 11 p.

Research output: Contribution to journalLiterature review

Open Access
File
Research
HIV
Medicine
Neoplasms
Proteins
37 Citations

Sphingosine 1-phosphate and sphingosine kinases in health and disease: recent advances

Pyne, S., Adams, D. R. & Pyne, N. J., 1 Apr 2016, In : Progress in Lipid Research. 62, p. 93-106 14 p.

Research output: Contribution to journalLiterature review

Open Access
File
Health
Protein Isoforms
Lipids
Cardiovascular system
Neurology
10 Citations

Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies

Evangelisti, C., Evangelisti, C., Buontempo, F., Lonetti, A., Orsini, E., Chiarini, F., Barata, J. T., Pyne, S., Pyne, N. J. & Martelli, A. M., 1 Nov 2016, In : Leukemia. 30, p. 2142–2151 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
Hematologic Neoplasms
Sphingosine
Sphingolipids
Ceramides
Neoplasms
2015
32 Citations
Bearings (structural)
Transition metals
Ligands
Catalysts
Metals
12 Citations

ATP as a cotransmitter in the autonomic nervous system

Kennedy, C., Sep 2015, In : Autonomic Neuroscience: Basic and Clinical . 191, p. 2-15 14 p.

Research output: Contribution to journalLiterature review

Open Access
File
Autonomic Nervous System
Adenosine Triphosphate
Purinergic P2X1 Receptors
Smooth Muscle
Neurotransmitter Agents
30 Citations

Choice and design of adjuvants for parenteral and mucosal vaccines

Savelkoul, H. F. J., Ferro, V. A., Strioga, M. M. & Schjins, V. E. J. C., 5 Mar 2015, In : Vaccines. 3, 1, p. 148-171 24 p.

Research output: Contribution to journalLiterature review

Open Access
File
Vaccines
Antigen-Presenting Cells
Antigen Presentation
Cytokines
T-Lymphocytes
8 Citations

Photoluminescent nanosensors for intracellular detection

De La Rica, R. & Kerr, C., 2015, In : Analytical Methods.

Research output: Contribution to journalLiterature review

Open Access
File
Nanosensors
Nanoparticles
Nanodiamonds
Dendrimers
Molecular Probes
15 Citations

Solution-based nanosensors for in-field detection with the naked eye

Paterson, S. & De La Rica, R., 2015, In : Analyst.

Research output: Contribution to journalLiterature review

Open Access
File
Nanosensors
Nanostructures
Nanostructured materials
Point-of-Care Systems
Molecules
61 Citations

Solvation thermodynamics of organic molecules by the molecular integral equation theory: approaching chemical accuracy

Ratkova, E. L., Palmer, D. S. & Fedorov, M. V., 2015, In : Chemical Reviews. 115, 13, p. 6312–6356 45 p.

Research output: Contribution to journalLiterature review

Open Access
File
Solvation
Integral equations
Thermodynamics
Physical chemistry
Molecules
59 Citations

The physiology of protein S-acylation

Chamberlain, L. H. & Shipston, M. J., 1 Apr 2015, In : Physiological Reviews. 95, 2, p. 341-376 36 p.

Research output: Contribution to journalLiterature review

Open Access
File
Acylation
Protein S
Protein Array Analysis
Proteins
Lipids
572 Citations

The re-emergence of natural products for drug discovery in the genomics era

Harvey, A., Edrada-Ebel, R. & Quinn, R. J., 23 Jan 2015, In : Nature Reviews Drug Discovery . 14, p. 111–129 19 p.

Research output: Contribution to journalLiterature review

Open Access
File
Drug Discovery
Genomics
Biological Products
Metabolomics
Proteins
2014
10 Citations

ESCRT function in cytokinesis: location, dynamics and regulation by mitotic kinases

Bhutta, M. S., McInerny, C. J. & Gould, G. W., 25 Nov 2014, In : International Journal of Molecular Sciences. 15, 12, p. 21723-21739 17 p.

Research output: Contribution to journalLiterature review

Open Access
File
Endosomal Sorting Complexes Required for Transport
Cytokinesis
classifying
Sorting
Microtubules
14 Citations

New links between S-acylation and cancer

Greaves, J. & Chamberlain, L., May 2014, In : Journal of Pathology. 233, 1, p. 4-6 3 p.

Research output: Contribution to journalLiterature review

Acylation
Enzymes
Lipoylation
Neoplasms
Intracellular Membranes
9 Citations

Novel treatment strategies for schizophrenia from improved understanding of genetic risk

Morris, B. J. & Pratt, J. A., Nov 2014, In : Clinical Genetics. 86, 5, p. 401-411 11 p.

Research output: Contribution to journalLiterature review

Open Access
File
Schizophrenia
MAP Kinase Signaling System
Synapses
Genes
Genome

Prediction of soluble heterologous protein expression levels in Escherichia coli from sequence-based features and its potential in biopharmaceutical process development

Dai, X., Guo, W., Long, Q., Yang, Y., Harvey, L., McNeil, B. & Bai, Z., 2014, In : Pharmaceutical Bioprocessing. 2, 3, p. 253-266 14 p.

Research output: Contribution to journalLiterature review

Escherichia coli
Proteins
Bioinformatics
Computational Biology
Genes
31 Citations

The role of sphingosine 1-phosphate in inflammation and cancer

Pyne, N. J., Ohotski, J., Bittman, R. & Pyne, S., Jan 2014, In : Advances in Biological Regulation. 54, p. 121-129 9 p.

Research output: Contribution to journalLiterature review

Open Access
File
Inflammation
Neoplasms
Lysosphingolipid Receptors
Sphingolipids
Knockout Mice
2013
13 Citations

Energetic charged particles above thunderclouds

Fuellekrug, M., Diver, D., Pincon, J-L., Phelps, A. D. R., Bourdon, A., Helling, C., Blanc, E., Honary, F., Harrison, R. G., Sauvaud, J-A., Renard, J-B., Lester, M., Rycroft, M., Kosch, M., Horne, R. B., Soula, S. & Gaffet, S., Jan 2013, In : Surveys in Geophysics. 34, 1, p. 1-41 41 p.

Research output: Contribution to journalLiterature review

thundercloud
Earth atmosphere
energetic particles
Charged particles
charged particles

Evolving views on protein palmitoylation (Comment on DOI 10.1002/bies.201300076)

Chamberlain, L., Nov 2013, In : BioEssays. 35, 11, p. 928 1 p.

Research output: Contribution to journalLiterature review

Lipoylation
Proteins
34 Citations

Metal-free syn-dioxygenation of alkenes

Rawling, M. & Tomkinson, N., 2013, In : Organic and Biomolecular Chemistry. 11, 9, p. 1434-1440 7 p.

Research output: Contribution to journalLiterature review

Open Access
File
Alkenes
alkenes
Metals
Osmium
osmium

Postgraduate education in clinical pharmacy in Europe

Kinnear, M., 1 Dec 2013, In : Newsletter - European Society of Clinical Pharmacy. 161, p. 5

Research output: Contribution to journalLiterature review

Pharmacy Education
Education
3 Citations

Sinking inside the box

Pritchard, D., May 2013, In : Journal of Fluid Mechanics. 722, p. 1-4 4 p.

Research output: Contribution to journalLiterature review

sinking
Buoyancy
buoyancy
boxes
Fluids
2012
89 Citations

Advancing schizophrenia drug discovery: optimizing rodent models to bridge the translational gap

Pratt, J., Winchester, C., Dawson, N. & Morris, B., Jul 2012, In : Nature Reviews Drug Discovery . 11, 7, p. 560-579 20 p.

Research output: Contribution to journalLiterature review

Drug Discovery
Rodentia
Schizophrenia
Pharmaceutical Preparations
Therapeutics

A fresh Look at crosslinked polymers

Cormack, P., 15 May 2012, In : Chemistry World. p. 62-63

Research output: Contribution to journalLiterature review

Polymers
E 2011
29 Citations

Atomic spectrometry update. Environmental analysis

Butler, O. T., Cairns, W. R. L., Cook, J. M. & Davidson, C. M., 2012, In : Journal of Analytical Atomic Spectrometry. 27, 2, p. 187-221 35 p.

Research output: Contribution to journalLiterature review

Spectrometry
Metal analysis
Water analysis
Trace analysis
Beverages

Development of clinical pharmacy education in UK

Kinnear, M., May 2012, In : Newsletter - European Society of Clinical Pharmacy. 155, p. 5 1 p.

Research output: Contribution to journalLiterature review

Pharmacy Education
Hospital Pharmacy Services
Formularies
284 Citations

Enzyme-responsive nanoparticles for drug release and diagnostics

De La Rica, R., Aili, D. & Stevens, M., Aug 2012, In : Advanced Drug Delivery Reviews. 64, 11, p. 967-978 12 p.

Research output: Contribution to journalLiterature review

Nanoparticles
enzymes
drugs
Nanostructures
nanoparticles
2217 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agnello, M., Al-Zeer, M. A., Chan, E., Coombs, G., Menzies, F. M. & Mottram, J., Apr 2012, In : Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journalLiterature review

Autophagy
Guidelines
Lysosomes
Eukaryota
Research Personnel
24 Citations
Open Access
Acanthocheilonema
Phosphorylcholine
Immune System
Glycoproteins
Autoimmunity
20 Citations

Measuring protein dynamics with ultrafast two-dimensional infrared spectroscopy

Adamczyk, K., Candelaresi, M., Robb, K., Gumiero, A., Walsh, M. A., Parker, A. W., Hoskisson, P. A., Tucker, N. P. & Hunt, N. T., Jun 2012, In : Measurement Science and Technology . 23, 6, 16 p., 062001

Research output: Contribution to journalLiterature review

Infrared Spectroscopy
Infrared spectroscopy
infrared spectroscopy
isotopic labeling
proteins
195 Citations

Molecularly-mediated assemblies of plasmonic nanoparticles for Surface-Enhanced Raman Spectroscopy applications

Guerrini, L. & Graham, D., 2012, In : Chemical Society Reviews. 41, 21, p. 7085-7107 23 p.

Research output: Contribution to journalLiterature review

Raman spectroscopy
Nanoparticles
Nanoscience
Suspensions
Nanotechnology

Parametric instability in scalar gravitational fields

Davies, T. B., Wang, C. H. -T., Bingham, R. & Mendonca, J. T., 10 Aug 2012, In : Modern Physics Letters A . 27, 24, 15 p., 1230023

Research output: Contribution to journalLiterature review

gravitational fields
scalars
neutron stars
tensors
excitation
31 Citations

Regulation and function of uncoordinated-51 like kinase proteins

Chan, E. Y., 1 Sep 2012, In : Antioxidants and Redox Signaling. 17, 5, p. 775-785 11 p.

Research output: Contribution to journalLiterature review

Autophagy
Protein Kinases
Phosphorylation
AMP-Activated Protein Kinases
Homeostasis
71 Citations

Sphingosine 1 phosphate signalling in cancer

Pyne, N. J., Tonelli, F., Lim, K. G., Long, J. S., Edwards, J. & Pyne, S., 2012, In : Biochemical Society Transactions. 40, 1, p. 94-100 7 p.

Research output: Contribution to journalLiterature review

Lysosphingolipid Receptors
Neoplasms
Tumors
Histone Deacetylase 2
Histone Deacetylase 1
13 Citations

Strategies and challenges involved in the discovery of new chemical entities during early-stage tuberculosis drug discovery

Coxon, G., Cooper, C. B., Gillespie, S. H. & McHugh, T. D., 22 Mar 2012, In : Journal of Infectious Diseases.

Research output: Contribution to journalLiterature review

Drug Discovery
Tuberculosis
Pharmaceutical Preparations
Biosynthetic Pathways
Infection
78 Citations

Surface enhanced Raman scattering for multiplexed detection

Dougan, J. A. & Faulds, K., 2012, In : Analyst. 137, 3, p. 545-554 10 p.

Research output: Contribution to journalLiterature review

Raman Spectrum Analysis
Raman scattering
scattering
Biomolecules
Complex Mixtures
18 Citations

Targeting sphingosine kinase 1 in cancer

Pyne, N. J., Tonelli, F., Lim, K. G., Long, J., Edwards, J. & Pyne, S., Jan 2012, In : Advances in Biological Regulation. 52, 1, p. 31–38 8 p.

Research output: Contribution to journalLiterature review

Prostatic Neoplasms
Neoplasms
Breast Neoplasms
Estrogen Receptors
Recurrence
23 Citations

Therapeutic implications of disorders of cell death signalling: membranes, micro-environment, and eicosanoid and docosanoid metabolism

Davidson, J., Rotondo, D., Rizzo, M. & Leaver, A., 6 Jun 2012, In : British Journal of Pharmacology. 166, 4, p. 1193-1210 18 p.

Research output: Contribution to journalLiterature review

Eicosanoids
Unsaturated Fatty Acids
Cell Death
Membranes
Pathologic Processes
2011
85 Citations

Advanced breast cancer incidence following population-based mammographic screening

Autier, P., Boniol, M., Middleton, R., Doré, J. F., Héry, C., Zheng, T. & Gavin, A., Aug 2011, In : Annals of Oncology. 22, 8, p. 1726-1735 10 p.

Research output: Contribution to journalLiterature review

Open Access
File
Breast Neoplasms
Incidence
Population
Mammography
Netherlands
37 Citations

Assemblies of functional peptides and their applications in building blocks for biosensors

De La Rica, R., Pejoux, C. & Matsui, H., 2011, In : Advanced Functional Materials. 21, 6, p. 1018-1026 9 p.

Research output: Contribution to journalLiterature review

Peptide Nanotubes
bioinstrumentation
Biosensors
assemblies
Peptides
6 Citations

Cellular trans-differentiation and morphogenesis towards the lymphatic lineage in regenerative medicine

Laco, F., Grant, M. H., Flint, D. J. & Black, R. A., Feb 2011, In : Stem Cells and Development. 20, 2, p. 181-195

Research output: Contribution to journalLiterature review

Growth Differentiation Factors
Vascular Endothelial Growth Factor C
Regenerative Medicine
Lymphedema
Interleukins
80 Citations

Currrent status and research strategies in tuberculosis drug development

Dover, L. G. & Coxon, G., 2011, In : Journal of Medicinal Chemistry. 54, 18, p. 6157–6165 9 p.

Research output: Contribution to journalLiterature review

Tuberculosis
Drug and Narcotic Control
Drug Discovery
Research
Pharmaceutical Preparations
25 Citations

Indirect modulation of neuronal excitability and synaptic transmission in the hippocampus by activation of proteinase-activated receptor-2

Gan, J., Greenwood, S. M., Cobb, S. R. & Bushell, T. J., Jul 2011, In : British Journal of Pharmacology. 163, 5, p. 984-994 11 p.

Research output: Contribution to journalLiterature review

PAR-2 Receptor
Synaptic Transmission
Hippocampus
Action Potentials
Ionotropic Glutamate Receptors