Faculty Of Science

  • United Kingdom

Research Output 1971 2019

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Meeting abstract
2018

A DNA-damaging lupus autoantibody synergizes with PARP inhibitors against DNA repair-deficient tumor cells

Rattray, Z., Patel, J. M., Noble, P. W., Dubljevic, V., Greenwood, D. L., Campbell, J. A. & Hansen, J. E., 30 Jul 2018, In : Cancer Research. 78, 13 (Supp), p. 2773 1 p.

Research output: Contribution to journalMeeting abstract

DNA Repair-Deficiency Disorders
Autoantibodies
DNA
Neoplasms
Poly(ADP-ribose) Polymerases
Open Access
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Protein-Tyrosine Kinases
Oxidative Stress
Fibroblasts
Neoplasms

Complex Interactions of excitatory and inhibitory stimuli in the vascular endothelium

Ratnayake, M., Wilson, C., Lee, M. D., Girkin, J. M., Saunter, C. M. & McCarron, J., 20 Apr 2018, In : FASEB Journal. 32, 1 Suppl., 1 p., 843.5

Research output: Contribution to journalMeeting abstract

Open Access
File
Vascular Endothelium
Phenylephrine
Acetylcholine
Endothelium
Angiotensins

Drug screening of biopsy-derived multicellular spheroids using microfluidic technology

Mulholland, T. E., McAllister, M., Patek, S., Flint, D., Underwood, M., Sim, A., Edwards, J. & Zagnoni, M., 31 Jul 2018, In : Cancer Research. 78, 13 (supplement), 1 p., 5024

Research output: Contribution to journalMeeting abstract

Open Access
File
Cellular Spheroids
Preclinical Drug Evaluations
Microfluidics
Technology
Biopsy

Parallel assessment of cell viability in cardiac and cancer cells following treatment with sunitinib

McBride, D., ALHAZMI, A. Y. M., Laovitthayanggoon, S., Boyd, M. & Currie, S., 26 Mar 2018, In : Heart . 104, S4, 6

Research output: Contribution to journalMeeting abstract

Open Access
File
Heart Neoplasms
Cell Survival
Fibroblasts
Therapeutics
Neoplasms

"Real world" populations compared to clinical trials: can electronic record linkage be used to identify trial eligible patients?

Baillie, K., Crearie, C., Mueller, T., Pan, J., Jones, R., Bennie, M. & Laskey, J., 1 Dec 2018, 24, 8 (Supplement)

Research output: Contribution to journalMeeting abstract

Open Access
File
Clinical Trials
Population
Benchmarking
Neoplasms
Scotland
2017

Ageing of the vascular endothelium: a novel role for CaMKIIδ

McCluskey, C., Macdonald, M. & Currie, S., 1 Apr 2017, In : Heart . 103, S2, p. A2 1 p., 3

Research output: Contribution to journalMeeting abstract

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Vascular Endothelium
Endothelial Cells
Aorta
Endothelium

An in vitro microfluidic model of microglia migration after stroke

White, S., Plevin, R., Zagnoni, M. & Carswell, H., 1 Apr 2017, In : Journal of Cerebral Blood Flow and Metabolism. 37, 1 (Suppl), 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
File
Microfluidics
Microglia
Glutamic Acid
Stroke
Time-Lapse Imaging

CoCl2 induced cardiotoxicity associated with CoCr alloy orthopaedic implants

Laovitthayanggoon, S., Grant, M. H., Henderson, C. J., Tate, R. J. & Currie, S., 1 Apr 2017, In : Heart . 103, S2, p. A4 1 p., 9

Research output: Contribution to journalMeeting abstract

Orthopedics
Fibroblasts
Metals
3T3 Cells
Ions
Open Access
File
Carica
Ficus
Neuroprotective Agents
Alzheimer Disease
Acrolein

Mitochondria has a role in regulating hypoxic-dependent cell proliferation in pulmonary cells and vascular remodelling

Coats, P., Plevin, R. & Burzangi, A., 30 Apr 2017, In : Heart . 103, Suppl 2, p. A6-A7 2 p.

Research output: Contribution to journalMeeting abstract

Open Access
Mitochondria
Cell Proliferation
Lung
Mitochondrial Dynamics
Messenger RNA
Open Access
MicroRNAs
Vascular Smooth Muscle
Smooth Muscle Myocytes
Cell Movement
Atherosclerosis
Carica
Ficus
Neuroprotective Agents
Metabolites
Purification

Pyrazine-fused triterpenoids block transient receptor potential ankyrin-1 (TRPA1) ion channel in vitro and inhibit TRPA1-mediated acute inflammation in vivo

Mäki-Opas, I., Hämäläinen, M., Moilainen, L. J., Haavikko, R., Ahonen, T., Alakurtti, S., Moreira, V., Muraki, K., Yli-Kauhaluoma, J. T. & Moilainen, E., 18 Sep 2017, In : Scandinavian Journal of Rheumatology. 46, 5

Research output: Contribution to journalMeeting abstract

Ankyrins
Pyrazines
Ion Channels
Inflammation
In Vitro Techniques
Veins
Transplants
Cell Proliferation
Vascular Smooth Muscle
Smooth Muscle Myocytes
Open Access
File
Drug Utilization
Clinical Pharmacology
Developing Countries
Education
Research
2016

Brain changing tubers: gene expression changes following mediaeval tuber consumption

Woods, N., Gebril, A., Simpson, A., Iannetta, P., Kenicer, G., Tate, R. J., Pickard, B., Gray, A. I. & Ferro, V. A., 14 Dec 2016, In : Planta Medica. 81, S 01, p. S1-S381

Research output: Contribution to journalMeeting abstract

Gene expression
Hypothalamus
Brain
RNA
Gene Expression

Calcium/calmodulin-dependent protein kinase II - does ageing mirror disease?

McCluskey, C., Salleh, H. & Currie, S., 30 Apr 2016, In : FASEB Journal. 30, 1 supplement, 767.3

Research output: Contribution to journalMeeting abstract

Open Access
File
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Calcium-Calmodulin-Dependent Protein Kinases
Mirrors
Aging of materials
Animals

Cobalt cardiotoxicity - effects on the contractile and non-contractile cells of the heart

Laovitthayanggoon, S., Tate, R., Currie, S. & Grant, M. H., 30 Apr 2016, In : FASEB Journal. 30, 1, 1 p., 178.7

Research output: Contribution to journalMeeting abstract

Open Access
File
Fibroblasts
Cobalt
Isoproterenol
Cells
Gentian Violet
Open Access
Metabolites
Metabolism
Rats
Hepatocytes
Mass spectrometers

Digital enablers for integrated care – a design workshop

Rimpiläinen, S., Boyle, J., Mackenzie, K., Arnell, G., Arias, V., Chute, C., Faulds, B., McIntyre, D. & Wood, A., 2016, In : International Journal of Integrated Care. 16, 6, 2 p.

Research output: Contribution to journalMeeting abstract

Open Access
File
chronic illness
Delivery of Health Care
Education
Type 2 Diabetes Mellitus
Caregivers

Effects of crude extracts from mushrooms on different cancer cell lines

Niwasabutra, K., Igoli, J. O., Young, L., Gray, A. I. & Ferro, V. A., 14 Dec 2016, In : Planta Medica. 81, S 01, p. S1-S381

Research output: Contribution to journalMeeting abstract

Agaricales
Complex Mixtures
Cells
Cell Line
Coriolaceae

Effects of trans-isoferulic acid and gallic acid on cardiac contractility: is there a role for CaMKII?

Currie, S., Qim, K., Mum, H., Campbell, S., MacKenzie, G., Mohd Salleh, M. H., Chellapan, D. & Candasamy, M., 6 Oct 2016, In : International Journal of Molecular Medicine. 38, S1, 149

Research output: Contribution to journalMeeting abstract

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Gallic Acid
Polyphenols
isoferulic acid

Inositol trisphosphate receptor contribution to ventricular cardiac fibroblast function in healthy and hypertrophied mouse hearts

Currie, S., Martin, T. P., Salleh, H., McCluskey, C. & Bushell, T. J., 30 Apr 2016, In : FASEB Journal. 30, 1 Supplement, 1 p., 1178.2

Research output: Contribution to journalMeeting abstract

Inositol
Fibroblasts
Phosphorylation
Angiotensin II
Echocardiography
Open Access
File
Replacement Arthroplasties
3T3 Cells
Cobalt
Fibroblasts
Metals

Phytochemical and biological investigation of Calliandra surinamensis as a potential treatment for diabetes

Alzahrani, A., Abbott, G., Young, L. C., Igoli, J., Gray, A. I. & Ferro, V. A., 14 Dec 2016, In : Planta Medica. 81, S 01, p. S1-S381

Research output: Contribution to journalMeeting abstract

ferulic acid
Phytochemicals
Hexanes
Medical problems
Methanol
Drug Utilization
Scotland
Anticoagulants
Atrial Fibrillation
Population
2015

Pro-inflammatory signalling in vascular endothelium: a novel role for CaMKIIdelta in ageing

McCluskey, C., Paul, A. & Currie, S., 30 Jun 2015, In : Heart . 101, S4, A100-A101

Research output: Contribution to journalMeeting abstract

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Vascular Endothelium
Interleukin-1beta
Human Umbilical Vein Endothelial Cells
Tumor Necrosis Factor-alpha
2014

Association between cardiovascular risk factors and concurrent depressive symptoms in cardiometabolic disease: a cross-sectional study

Jani, B. D., Cavanagh, J., Barry, S., Der, G., Sattar, N. & Mair, F. S., 19 Nov 2014, In : Lancet. 384, Supplement 2, p. S40 1 p.

Research output: Contribution to journalMeeting abstract

Cross-Sectional Studies
Depression
Blood Pressure
Coronary Disease
Primary Health Care

Atomic force microscopy (AFM) analysis of nanocarrier–cell interaction

Kemp, O., Grant, H. & Lamprou, D., 10 Sep 2014, In : Toxicology Letters. 229, Supplement, p. S67 1 p., P-1.86

Research output: Contribution to journalMeeting abstract

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Fibroblasts
Cell Proliferation
Ryanodine Receptor Calcium Release Channel
Angiotensin II

Highly active iridium(I) complexes for novel beta-selective hydrogen isotope exchange processes

Kerr, W. & Mudd, R. J., 1 Mar 2014, In : Journal of Labelled Compounds and Radiopharmaceuticals. 57, 3, p. 185-186 2 p.

Research output: Contribution to journalMeeting abstract

Iridium
Isotopes
Hydrogen
Bearings (structural)
phosphine

Hypoxia mediated signalling in vein graft remodelling and failure

Huq, M., Currie, S. & Coats, P., 31 Dec 2014, In : Heart . 100, S4

Research output: Contribution to journalMeeting abstract

Veins
Transplants
Tunica Intima
Ischemia
Saphenous Vein

Initiatives to improve prescribing efficiency in China and their influence: cardio-cerebral vascular medicines as a case history to provide future direction

Godman, B., Zeng, W., Zhen, J., Feng, M., Finlayson, A. & Campbell, S., Jul 2014, In : Basic and Clinical Pharmacology and Toxicology . 115, Suppl 1, 1 p., 105

Research output: Contribution to journalMeeting abstract

Open Access
File
Cardiology
Health Expenditures
Chinese Traditional Medicine
Medicine
China
Iridium
Sulfonamides
Labeling
Nitro Compounds
Facings

Laser acceleration of protons using multi-ion plasma gaseous targets and its medical implications

Shao, X., Liu, T-C., Liu, C-S., Eliasson, B., Hill, W., Wang, J. & Chen, S-H., 27 Oct 2014, In : Bulletin of the American Physical Society. 59, 15

Research output: Contribution to journalMeeting abstract

proton beams
protons
lasers
foils
ions
2 Citations

Spot size dependence of laser accelerated protons in thin multi-ion foils

Liu, T-C., Shao, X., Liu, C-S., Eliasson, B., Wang, J. & Chen, S-H., 29 Oct 2014, In : Bulletin of the American Physical Society. 59, 15

Research output: Contribution to journalMeeting abstract

foils
protons
lasers
ions
laser beams
2013

An analysis of mechanisms of central nervous system infiltration in acute lymphoblastic leukaemia using primary cells xenografted into immunodeficient mice

Yousafzai, Y. , Williams, M. , Rehe, K. , Le Brocq, M. , Bomken, S. , Sinclair, P. , Dormon, K. , Masic, D. , Archer, L. , Watt, J. , Perry, T. , Weston, V. , Kearns, P. , Blair, H. , Russel, L. , Heidenreich, O. , Irving, J. , Vormoor, J. , Gibson, B. , Graham, G. & 1 others Halsey, C., 5 Dec 2013, In : Blood. 122, 21, p. 3899 1 p.

Research output: Contribution to journalMeeting abstract

Neurology
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Infiltration
Central Nervous System
Chemokine Receptors

Co–Cr wear products derived from metal-on-metal articulations induce apoptosis on monocyte-like U937 cells

Posada Estefan, O. M., Grant, H. & Tate, R. J., Aug 2013, In : Toxicology Letters. 28, Suppl, p. S75 1 p.

Research output: Contribution to journalMeeting abstract

Chromium Alloys
Cobalt alloys
Chromium alloys
U937 Cells
Cell death

Phosphatidylserine-containing liposomes: modulators of rhinovirus induced inflammatory responses

Stokes, C. A., Glanville, N., Kaur, R., Hume, R. D., Robinson, D., Perrie, Y., Edwards, M. R., O'Donnell, V., Harwood, J., Parker, L. C. & Sabroe, I., 1 Dec 2013, In : Immunology. 140, S1, p. 108 1 p.

Research output: Contribution to journalMeeting abstract

The effect of cell ingrowth on the mechanical behaviour of anchored collagen gels

Busby, G., Riches, P., Grant, M. & MacKay, S., Aug 2013, In : International Journal of Artificial Organs. 36, 8, p. 567 O106

Research output: Contribution to journalMeeting abstract

Collagen
Gels
Mechanical properties
Cell proliferation
Tissue Engineering
2012

A fusion protein based pneumococcal vaccine

Ma, J., Ross, K. S., Ritchie, R., Douce, G. & Mitchell, T. J., Sep 2012, In : Immunology. 137, 1 special issue, p. 753-753 1 p.

Research output: Contribution to journalMeeting abstract

Posters
Pneumococcal Vaccines
Allergy and Immunology
Vaccines
Proteins
3 Citations

Characterization of the very high energy electrons, 150-250 MeV (VHEE) beam generated by ALPHA-X laser wakefield accelerator beam line for utilization in Monte Carlo simulation for biomedical experiment planning

Moskvin, V., Subiel, A., Desrosiers, C., Wiggins, M., Maryanski, M., Mendonca, M., Boyd, M., Sorensen, A., Cipiccia, S., Issac, R., Welsh, G., Brunetti, E., Aniculaesei, C. & Jaroszynski, D. A., Jun 2012, In : Medical Physics. 39, 6, p. 3813-3814 2 p.

Research output: Contribution to journalMeeting abstract

Lasers
Electrons

Development of biomaterials for cellular differentiation using a metabolomics approach

Alakpa, E. V., Burgess, K., Jayawarna, V., Ulijn, R. & Dalby, M., Sep 2012, In : Journal of Tissue Engineering and Regenerative Medicine. 6, special issue 1, p. 238-238 1 p.

Research output: Contribution to journalMeeting abstract

Metabolomics
Biocompatible Materials
Stem cells
Biomaterials
Metabolome

Galactosylated poly(ethylene glycol) as a scaffold for primary hepatocytes.

Hamilton, C., Henderson, C. J., Ulijn, R. V. & Grant, M. H., Jul 2012, In : European Cells and Materials. 23, Suppl 4, p. 30 1 p.

Research output: Contribution to journalMeeting abstract

Ethylene Glycol
Scaffolds
Polyethylene glycols
Hepatocytes
Asialoglycoprotein Receptor

In silico screening of bioactive molecules using molecular integral equation theory

Palmer, D. S., Frolov, A. I., Ratkova, E. L. & Fedorov, M. V., 25 Mar 2012, In : Abstracts of papers - American Chemical Society. 243, 385-COMP

Research output: Contribution to journalMeeting abstract

Integral equations
Screening
Molecules

Protective role of MAP kinase phosphatase 2 (MKP-2) in a model of collagen antibody induced arthritis

Schroeder, J., Ross, K., Alexander, J., Lawrence, C. E. & Plevin, R., Sep 2012, In : Immunology. 137, 1 special issue, p. 585-585 1 p.

Research output: Contribution to journalMeeting abstract

Posters
Experimental Arthritis
Mitogen-Activated Protein Kinase 1
Myeloid Cells
Allergy and Immunology

Systems biology approaches to metabolic engineering in Streptomycetes: the Phosphoenolpyruvate-Pyruvate-Oxaloacetate node of primary metabolism

Hiltner, J. K., Cruz, J. C. S., Fernandez-Martinez, L., Petkovic, H., Hunter, I. S. & Hoskisson, P. A., Sep 2012, In : FEBS Journal. 279, S1, p. 264-264 1 p.

Research output: Contribution to journalMeeting abstract

Metabolic engineering
Metabolic Engineering
Oxaloacetic Acid
Phosphoenolpyruvate
Systems Biology

Tetrahydrobiopterin and electron transfer in NO synthase

Daff, S., Gazur, B., Papale, D., McInnes, C., Morthala, R. R., Gibson, C. L. & Suckling, C. J., 15 Jul 2012, In : Nitric Oxide: Biology and Chemistry . 27, supplement, p. S5-S5 1 p.

Research output: Contribution to journalMeeting abstract

Nitric Oxide Synthase
Electrons
Pterins
Molecular oxygen
Oxygen

The role of mast cells in protection against Leishmania donovani infection

Carter, K., Ross, K., Tacchini-Cottier, F. & Lawrence, C., Sep 2012, In : Immunology. 137, 1 special issue, p. 562-563 2 p.

Research output: Contribution to journalMeeting abstract

Leishmania donovani
Posters
Cytoprotection
Myeloid Cells
Allergy and Immunology