Data for: "Self-assembling silk hydrogels integrate with host tissue and support endogenous cell proliferation after a focal cerebral ischaemic stroke"

  • Natalia Gorenkova (Creator)
  • Hilary Carswell (Supervisor)
  • Philipp Seib (Supervisor)



Data include:
1) Prizm files (.pzfx) containing row data measurements and graphs , and
2) Pictures (as .jpg or .tiff) of brain tissue sections, cutted on microtome and mounted on slides and processed through histological and immunofluorescent staining (single channel or merged channels), or a pictures of a whole clear brain sections mounted on slides.

Animal weight and neurological deficit data were expressed as means ± standard error of means (SEM), t-test, one-way ANOVA with Bonferroni post-hoc test and regression analysis for infarct vs. number of Ki67+ cells were done using Prism 6 (GraphPad). A P value of <.05 was considered significant.

Haematoxylin and eosin staining was performed in order to detect the silk hydrogel graft in the cavity, as well as for lesion volume measurement. The whole brain images were used as guidance to lesion/graft localisation and were taken with Sumsung Galaxy Neo camera (CMOS 16.0 MP resolution, with f/1.9 aperture).

All other immunofluorescent images (4x-40x) were captured and analysed using WinFluor V3.9.1 fluorescence imaging programme (Nikon Eclipse E600).

Data access pending publication (data released 06/12/18)
Date made available9 Nov 2017
PublisherUniversity of Strathclyde
Date of data productionJan 2016 - Apr 2017

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