Activity: Participating in or organising an event types › Organiser of special symposia
G protein-coupled receptors (GPCRs) regulate a wide variety of physiological processes and are one the most intensively studied drug target. GPCRs are the most successful drug target, with ~34% of currently approved drugs have a GPCR as their target. Despite this, only 27% of GPCRs have been successfully targeted in the clinic leaving a large proportion of physiologically relevant receptors without drugs that can modify their activity. In this session, current trends in GPCR drug discovery will be discussed, opening up a focus on specific GPCRs that have not yet been explored in clinical trials and have untapped therapeutic potential in a range of disease indications including viral GPCRs in glioblastoma, free fatty acid receptors in metabolic disorders and the orphan receptor GPR35 in inflammatory bowel disease.